Spatial Perseveration in Dementia with Lewy Bodies by Frédéric Assal, Patrick McNamara

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Preclinical Polymodal Hallucinations for 13 Years before Dementia with Lewy Bodies by Carlo Abbate, Pietro Davide Trimarchi, Silvia Inglese, Niccolò Viti, Alessandra Cantatore, Lisa De Agostini, Federico Pirri, Lorenza Marino, Renzo Bagarolo, Daniela Mari

“…We describe a case of dementia with Lewy bodies (DLB) that presented long-lasting preclinical complex polymodal hallucinations. …”
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REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) by Po-Chi Chan, Hsun-Hua Lee, Chien-Tai Hong, Chaur-Jong Hu, Dean Wu

“…RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. …”
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An overview of methods for the treatment and diagnosis of dementia with Lewy bodies. Clinical case analysis by M. Š. Markevičiūtė, M. Karnickas, A. Bagdonaitė

Subjects: “…dementia with Lewy bodies…”
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Metabolic Risk Factors of Alzheimer’s Disease, Dementia with Lewy Bodies, and Normal Elderly: A Population-Based Study by Chih-Kuang Cheng, Yu-Chien Tsao, Yuan-Chih Su, Fung-Chang Sung, Hsu-Chih Tai, Woon-Man Kung

“…Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) share many risk factors. Evidence suggests that metabolic risk factors are important to AD; however, their association with DLB is unclear. …”
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Lewy body diseases and the gut by Timothy R. Sampson, Malú Gámez Tansey, Andrew B. West, Rodger A. Liddle

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Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases by Fangyuan Wang, Zhou Jing, Qingyi Wang, Minghe Li, Bingqi Lu, Ao Huo, Chenglin Zhao, Huanyu Zhou, Wulong Liang, Weihua Hu, Xudong Fu

“…Bidirectional causality was observed between dementia with Lewy bodies and C21orf33. Conclusions Using MR, we identified significant links between mitochondrial protein gene mutations and the risk of neurodegenerative diseases. …”
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Ethiologic diagnosis of dementia syndrome. by Erélido Hernández Valero, María Octavina Rodríguez Roque

“…Numbers are presented, and a series of valuations about dementia, the slight cognitive aggravation, Alzheimer disease, vascular dementia, dementia by Lewy bodies, and front temporal dementia, as well as other kinds of dementia. …”
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Therapeutic Application of rTMS in Atypical Parkinsonian Disorders by Chrysi Petsani, Athina-Maria Aloizou, Vasileios Siokas, Lambros Messinis, Eleni Peristeri, Christos Bakirtzis, Grigorios Nasios, Efthimios Dardiotis

“…The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (LBD). APDs are characterized by a variety of symptoms and a lack of disease modifying therapies; their treatment thus remains mainly symptomatic. …”
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Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis by Simone A. van den Berge, Josta T. Kevenaar, Jacqueline A. Sluijs, Elly M. Hol

“…We have examined these proteins by immunohistochemistry in the frontal cortex and by Western blot in CSF of cases with PD, PD with dementia (PDD), dementia with Lewy bodies (DLB) and nondemented controls. We were neither able to detect an increase in cortical astrogliosis in PD, PDD, or DLB nor could we observe a correlation between the extent of astrogliosis and the degree of dementia. …”
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Cognitive profile in mild cognitive impairment with Lewy bodies by Shuai Liu, Chunyan Liu, Xiao-Dan Wang, Huiru Lu, Yong Ji

“…In line with the literature on Dementia with Lewy bodies, our results showed lower performance on tests for visuoconstructive and executive function, whereas memory remained relatively spared in the early period.…”
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Resting State fMRI: A Valuable Tool for Studying Cognitive Dysfunction in PD by Kai Li, Wen Su, Shu-Hua Li, Ying Jin, Hai-Bo Chen

“…In this review, we summarize rs-fMRI studies on cognitive function in PD and discuss the strong potential of rs-fMRI in this area. rs-fMRI can help reveal the pathophysiology of cognitive symptoms in PD, facilitate early identification of PD patients with cognitive impairment, distinguish PD dementia from dementia with Lewy bodies, and monitor and guide treatment for cognitive impairment in PD. …”
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Erectile Dysfunction Preceding Clinically Diagnosed α-Synucleinopathies: A Case-Control Study in Olmsted County by Shemonti Hasan, Michelle M. Mielke, J. Eric Ahlskog, James Bower, Pierpaolo Turcano, Rodolfo Savica

“…Autonomic symptoms are common in α-synuclein disorders: multiple system atrophy (MSA), Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and Parkinson’s disease with dementia (PDD). …”
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Prevalence and Associated Factors of Visual Hallucinations in Patients with Vascular Cognitive Impairment by Chih-Lin Chen, Min-Hsien Hsu, Chao-Hsien Hung, Pai-Yi Chiu, Chung-Hsiang Liu

“…Visual hallucinations (VHs) are striking features for dementia, especially dementia with Lewy bodies (DLB). We aimed to study the frequency and associated factors of VH in vascular cognitive impairment (VCI) and investigate the feasibility of clinically diagnosing the mixed pathology of VCI with DLB. …”
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Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities by Filippa Lo Cascio, Suhyeorn Park, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Nikita Shchankin, Cynthia Jerez, Naomi Moreno, Alice Bittar, Rhea Xavier, Yingxin Zhao, Cankun Wang, Hongjun Fu, Qin Ma, Mauro Montalbano, Rakez Kayed

“…Abstract Aggregation of microtubule-associated tau protein is a distinct hallmark of several neurodegenerative disorders such as Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), and progressive supranuclear palsy (PSP). …”
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White matter hyperintensities and cholinergic degeneration as Lewy body disease by Sungwoo Kang, Seun Jeon, Yeoju Kim, Su‐Hee Jeon, Minsun Choi, Young‐gun Lee, Mijin Yun, Byoung Seok Ye

“…Abstract Objective Although basal forebrain (BF) cholinergic degeneration and white matter hyperintensities (WMHs) are important in neurodegeneration in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), their relationships with dopaminergic degeneration and clinical manifestations remain unclear. …”
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Glucose Metabolic Brain Network Differences between Chinese Patients with Lewy Body Dementia and Healthy Control by Danyan Chen, Jiaying Lu, Hucheng Zhou, Jiehui Jiang, Ping Wu, Qihao Guo, Jingjie Ge, Huiwei Zhang, Kuangyu Shi, Chuantao Zuo

“…Dementia with Lewy bodies (DLB) is the second most common degenerative dementia of the central nervous system. …”
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Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional studyResearch in context by Kenneth Marek, David S. Russell, Luis Concha-Marambio, Seung Ho Choi, Danna Jennings, Michael C. Brumm, Christopher S. Coffey, Ethan Brown, John Seibyl, Matthew Stern, Claudio Soto, Andrew Siderowf

“…Summary: Background: Synuclein pathology in neurodegenerative diseases, such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB), begins years before motor or cognitive symptoms arise. …”
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Characterization of Sleep Structure and Autonomic Dysfunction in REM Sleep Behavior Disorder by Nicla Mandas, Maximiliano Mollura, Giulia Baldazzi, Parisa Sattar, Maria Mura, Elisa Casaglia, Michela Figorilli, Laura Giorgetti, Pietro Mattioli, Francesco Calizzano, Francesco Fama, Dario Arnaldi, Monica Puligheddu, Danilo Pani, Riccardo Barbieri

“…<italic>Goal:</italic> REM Sleep Behavior Disorder (RBD) is a REM parasomnia that is associated to high risk of developing &#x03B1;-synucleinopathies, as Parkinson&#x0027;s disease (PD) or dementia with Lewy bodies, over time. This study aims at investigating the presence of autonomic dysfunctions in RBD subjects, with and without PD, by assessing their sleep structure and autonomous nervous system activity along the different sleep stages. …”
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Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…Of the 18,823 cases analyzed, the most common diagnoses were Alzheimer's Disease (83.44%), Dementia with Lewy Bodies (5.37%), and Frontotemporal Dementia (13.40%). …”
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