Healthcare trajectories of aging individuals during their last year of life: application of process mining methods to administrative health databases by Delphine Bosson-Rieutort, Alexandra Langford-Avelar, Juliette Duc, Benjamin Dalmas

“…It provides a visual representation of the processes recorded in various health system databases and allows for the visualization of the different trajectories of healthcare utilization.…”
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Fluid balance and clinical outcomes in patients with aortic dissection: a retrospective case-control study based on ICU databases by Tao Chen, Peng Qiu, Yixuan Li, Xinwu Lu, Zhaoyu Wu, Zhijue Xu, Hongji Pu, Jiahao Lei, Zhuojing Zhang, Xinrui Yang, Ruihua Wang

“…This paper explores the role of fluid management in the clinical care of AD patients, which has been unclear despite the substantial existing research that has been conducted on the treatment of AD.Design A retrospective case-control study using data for AD patients from public databases.Setting Two public intensive care unit (ICU) databases with hospital courses from the USA, Medical Information Mart for Intensive Care (MIMIC)-IV critical care dataset and the eICU Collaborative Research Database, with data from 2008 to 2019.Participants A total of 751 adult AD patients with detailed fluid management records from two databases were included.Interventions The mean 24-hour intake and output were calculated by dividing the total amount of intake and output by the number of days in the ICU, respectively. …”
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Safety profiles of sevoflurane in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database by Chuang Yang, Bangjian Deng, Qiang Wen, Pei Guo, Xiang Liu, Chen Wang

“…We also compared the adverse events related to sevoflurane between pediatric and adult populations.ResultsThe FAERS database yielded 21,838,627 adverse event reports for children, with 474 involving sevoflurane as the primary suspect. …”
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Database and geospatial mapping study of those eligible for extracorporeal cardiopulmonary resuscitation in the Thames Valley Region, England by Oscar Millerchip, Jasper Eddison, Alex Rosenberg, Jon Bailey, James Raitt

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Corrigendum: Adverse drug events (ADEs) risk signal mining related to eculizumab based on the FARES database by Xi-Feng Wang, Lu-Ri Bao, Ta-La Hu, Rui-Feng Xu, Wu-Niri Gao, Jing-Yuan Wang, Jian-Rong Zhao, Zhen-Li Fu, Shu-Fang Wang, Yan Meng

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Real-world enrollment for a prospective clinico-genomic database using a pragmatic technology-enabled platform by Alexia Exarchos, Ariel B. Bourla, Maneet Kaur, Katja Schulze, Sophia Maund, Yi Cao, Yihua Zhao, Elizabeth H. Williams, Sarah C. Gaffey, Richard Zuniga, Shaily Lakhanpal, Vladan Antic, Michelle Doral, Johanna Sy, Neal J. Meropol, Anne C. Chiang

“…The objective was to evaluate the feasibility of a pragmatic, technology-enabled platform at community-based research sites for development of a prospective clinico-genomic database supported by centralized electronic health record (EHR)–based patient ascertainment and data processing. …”
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Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…This study aimed to evaluate the adverse events (AEs) of IDH inhibitors based on the Food and Drug Administration Adverse Event Reporting System (FAERS) database. Methods AE reports for IDH inhibitors (enasidenib, ivosidenib, and olutasidenib) were collected and analyzed from the time of launch through the first quarter of 2024. …”
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Clinical and Cost Burden of Primary Sjögren’s Syndrome: Descriptive Analysis Using a US Administrative Claims Database by Sue Perera, Liyuan Ma, Raj Punwaney, Sulabha Ramachandran

“…**Methods:** This was a retrospective cohort study (HO-15-16077) conducted in the US Truven MarketScan Commercial database. We report descriptive data from employees and their families, as covered by employer-sponsored medical insurance. …”
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Evaluating the association of depressive symptoms on serum folate and erythrocyte folate levels based on the 2017–2020 NHANES database by Yunhong Yang, Huaqian Qi, Jiahao Zhang, Jie Jia, Yunsong Yang, Hong Zhao

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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

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Problems in publication of results of scientific research, their visibility and possible frauds by Živković Živan

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L-shaped association of body mass index with prognosis in individuals with sepsis: a multicenter cohort study by Kunping Cui, Xiangnan Teng, Wei liu, Xiaoxiao Zhao, Shanling Xu, Lang Bai

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Outcomes of Hospitalized COVID-19 Patients by Risk Factors: Results from a United States Hospital Claims Database by Peter J. Mallow, Kathy W. Belk, Michael Topmiller, Edmond A. Hooker

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Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database by Hideo Yasunaga, Hirotaka Chikuda, Kiyohide Fushimi, Hiromasa Horiguchi, Toru Akiyama, Kazuo Saita

“…Objective To examine the incidence of vertebral osteomyelitis (VO) and the clinical features of VO focusing on risk factors for death using a Japanese nationwide administrative database.Design Retrospective observational study.Setting Hospitals adopting the Diagnosis Procedure Combination system during 2007–2010.Participants We identified 7118 patients who were diagnosed with VO (International Classification of Diseases, 10th Revision codes: A18.0, M46.4, M46.5, M46.8, M46.9, M48.9 and M49.3, checked with the detailed diagnoses in each case and all other codes indicating the presence of a specific infection) and hospitalised between July and December, 2007–2010, using the Japanese Diagnosis Procedure Combination database.Main outcome measures The annual incidence of VO was estimated. …”
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Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports by Alessandro Ceschi, Roberta Noseda, Raffaela Bertoli, Laura Müller

“…We retrieved the individual case safety reports reporting HLH in association with ipilimumab, nivolumab, pembrolizumab, atezolizumab, avelumab or durvalumab, gathered in the database starting from the ICIs’ approval dates by the US Food and Drug Administration. …”
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Examining the relationship between incidence and mortality for commonly diagnosed cancers in the USA: an observational study using population-based SEER database by H Gilbert Welch, Adewole S Adamson, Vishal R Patel

“…We assessed the relationship between incidence and mortality for commonly diagnosed cancers in the USA.Design Population-based observational study of US counties.Setting and participants The Surveillance, Epidemiology and End Results (SEER) database was used to obtain incidence (2000–2016) and mortality (2002–2018) data for the 12 most commonly diagnosed non-haematologic cancers.Outcome measures County-level correlation between cancer incidence and mortality. …”
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Mapping the global clinical landscape of stem cell therapies for neurological diseases from 1998 to 2023: an analysis based on the Trialtrove database by Shenzhong Jiang, Xinjie Bao, Chunlong Zhong, Renzhi Wang

“…Based on the Trialtrove database, we retrospectively analyzed 530 clinical trials initiated by the end of 2023.…”
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COVID-19 in the years 2020 to 2022 in Germany: effects of comorbidities and co-medications based on a large-scale database analysis by Roland Linder, Jonas Peltner, Anatoli Astvatsatourov, Willy Gomm, Britta Haenisch

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