Impact of White Blood Cell Count After Percutaneous Coronary Intervention on Long-Term Prognosis in Patients with Unstable Angina Pectoris: A Single-Center Retrospective Observatio... by Zhang Z, Wang H, Wang R, She Z, Liang X, Liu H, Kou X, Wang S

“…The Kaplan–Meier method and COX proportional regression model were used to evaluate the association between the incidence of 5-year endpoint events and post-PCI leukocytosis.Results: Leukocytosis and neutrocytosis within 24 hours after PCI were observed in majority of patients with UA, while lymphocyte count significantly decreased after PCI in those patients. …”
Get full text

Association Between Liver Fibrosis and Risk of Incident Stroke and Mortality: A Large Prospective Cohort Study by Zijie Wang, Zhitao Gong, Jianshang Wen, Shanyu Zhang, Xiao Hu, Wenliang Guo, Yanghua Tian, Qi Li

“…We identified participants at high probability of advanced liver fibrosis using the Fibrosis‐4 index >2.67 or aspartate aminotransferase to platelet ratio index ≥1.0. Multivariable Cox proportional hazard regression analyses were conducted to estimate hazard ratios (HRs) for liver fibrosis with the incidence of major stroke types, stroke‐related death, and all‐cause death. …”
Get full text

Association of Serum Ferritin Levels With Obstructive Sleep Apnea in Overweight/Obese US Populations: A Population-Based Study From the NHANES by Zhang Y, Zhou P, Xu C, Su H, Li R, Sun L, Yang Y

“…Kaplan-Meier survival analyses and Cox proportional hazards regression examined the relationship between ferritin levels and all-cause mortality in OSA patients.Results: After adjusting for potential confounding factors, we found that ln-transformed ferritin levels were associated with an increased risk of OSA (Q4 vs Q2: OR = 1.07, 95% CI: 1.01– 1.13, P = 0.020, P for trend = 0.010). …”
Get full text

Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study by Wei Yin, Zhuochen Lin, Wei-Jie Gong, Wen-Xuan Wang, Ying-Ying Zhu, Yi-Lin Fu, Han Yang, Jin-Xin Zhang, Peng Lin, Ji-Bin Li

“…Generalized linear regression models were used for AAO of LC outcomes and Cox models for mortality outcomes. Results Participants over 60 years old could still benefit from smoking cessation to prolong AAOs (β = 1.613 for men, P = 0.003; β = 1.533 for women, P = 0.018). …”
Get full text

Influence of cardiovascular health behaviors and factors on the incidence of hypertension in young and middle-aged population by Yan Lei, Li Ying, Wang Jiangang, Yang Pingting

“…The incidence of hypertension was monitored, and a multivariate Cox proportional hazards regression model was applied. …”
Get full text

Contribution of type 2 diabetes to major adverse cardiovascular events (MACE) in a long-term observational study with different stages of atherosclerosis by Arthur Mader, Dario Haeberli, Barbara Larcher, Jörn F. Dopheide, Christoph H. Saely, Christine F. Heinzle, Peter Amann, Marc Schindewolf, Andreas Festa, Heinz Drexel

“…Further, MACE occurred more frequently in group III (58.1%), than group II (34.1%) or group I (19.1%) (group I vs. group II vs. group III, p < 0.001). In a cox-regression-model, T2DM was a significant predictor of MACE in univariate analyses (HR = 2.43 [1.88–3.14], p < 0.001) and after multivariate adjustment for cardiovascular risk factors, as well as the different grades of atherosclerosis (HR = 1.37 [1.02–1.84], p = 0.034). …”
Get full text

Soluble galectin-4 in colorectal cancer is associated with tumor progression, but is not a predictor of the disease outcome by Elena Y. Yakunina, Olga V. Kovaleva, Ruslan A. Zukov, Alexey N. Gratchev, Sergey S. Salamatin, Sofya O. Kochkina, Zaman Z. Mammadli, Nikolay E. Kushlinskii

“…The galectin-4 levels were higher at advanced stages of the disease (p = 0.002) and in the presence of distant metastases (p 0.0001). Cox regression analysis showed that tumor size and distant metastases were independent prognostic factors (hazard ratio (HR) = 3.87; p = 0.0439; HR = 720.4; p = 0.0062, respectively) associated with decreased survival. …”
Get full text

Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…Among the participants, 3,621 individuals had their survival status recorded, allowing us to employ Cox proportional hazards regression models in order to ascertain the association between OBS and the all-cause mortality within the subset of individuals with MetS. …”
Get full text

Baseline 18F-FDG PET/CT parameters in predicting the efficacy of immunotherapy in non-small cell lung cancer by Lu Zheng, Lu Zheng, Yanzhu Bian, Yanzhu Bian, Yujing Hu, Congna Tian, Xinchao Zhang, Shuheng Li, Xin Yang, Yanan Qin

“…The Kaplan–Meier curve was employed to compare progression-free survival (PFS) and overall survival (OS) between the ICIs and non-ICIs group and to assess the impact of variables on PFS and OS in the ICIs group. Multivariate Cox proportional hazards regression analysis was conducted with parameters significantly associated with survival in univariate analysis.ResultsSignificant differences were observed in PFS (χ2 = 11.910, p = 0.0006) and OS (χ2 = 8.343, p = 0.0039). …”
Get full text

Registro SBR-AF: Preditores de Recorrência de Taquiarritmia Atrial após Primeira Ablação por Cateter na Fibrilação Atrial by Caique M. P. Ternes, Luis E. Rohde, Alexander Dal Forno, Andrei Lewandowski, Helcio Garcia Nascimento, Gabriel Odozynski, Claudio Ferreira, Enrico G. Ferro, Carisi A. Polanczyk, André Zimerman, Lucas S. Faganello, Eric Pasqualotto, Grazyelle Damasceno, Leandro I. Zimerman, Andre d’Avila

“…O modelo de riscos proporcionais de Cox avaliou preditores independentes de recorrência. …”
Get full text

Sex-differences in the risk of carpal tunnel syndrome: results from a large Ontario, Canada worker cohort by Fanni R. Eros, Paul A. Demers, Jeavana Sritharan

“…A total of 792,769 workers were included in the analytical cohort. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CI) for CTS by occupation and industry, adjusted for age and birth year, stratified by sex. …”
Get full text

Construction of the bromodomain-containing protein-associated prognostic model in triple-negative breast cancer by Wei Chen, Yushuai Yu, Chenxi Wang, Zirong Jiang, Xiewei Huang, Yidan Lin, Hongjing Han, Qing Wang, Hui Zhang

“…Prognostic genes were selected through univariate Cox regression and least absolute shrinkage and selection operator (LASSO) regression analyses to construct a risk model and calculate risk scores. …”
Get full text

Upregulated SAE1 Drives Tumorigenesis and Is Associated with Poor Clinical Outcomes in Breast Cancer by Hong Liu, Jing Wang, Yunhai Li, Feng Luo, Lei Xing

“…Patients with SAE1 overexpression had a worse overall survival (OS), recurrence-free survival (RFS), and distant metastasis-free survival compared with lower expression patients. Multivariate Cox regression analysis showed that SAE1 may be an independent prognostic factor for OS of BC patients. …”
Get full text

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia by Tim Kong, Angelo B. A. Laranjeira, Christopher T. Letson, LaYow Yu, Shuyang Lin, Jared S. Fowles, Daniel A. C. Fisher, Sherwin Ng, Wei Yang, Fan He, Minyoung Youn, Kailen Mark, Ana San Jose, Jingxian Liu, Alexander B. Kim, Maggie J. Cox, Mary C. Fulbright, Aarthi Jayanthan, Gerrit Los, Stacey L. Rentschler, Li Ding, Kathleen M. Sakamoto, Sandra E. Dunn, Grant A. Challen, Stephen T. Oh

Get full text

Green sanctuaries: residential green and garden space and the natural environment mitigate mental disorders risk of diabetic patients by Erxu Xue, Jianhui Zhao, Jingyu Ye, Jingjie Wu, Dandan Chen, Jing Shao, Xue Li, Zhihong Ye

“…Residential green and garden space modeled from land use data and the natural environment from Land Cover Map were assigned to the residential address for each participant. Cox proportional hazards model was used to analyze the associations between nature exposures and mental disorders of diabetes. …”
Get full text

The Relationship between Body Mass Index and Incident Diabetes Mellitus in Chinese Aged Population: A Cohort Study by M. L. Tang, Y. Q. Zhou, A. Q. Song, J. L. Wang, Y. P. Wan, R. Y. Xu

“…DM was confirmed if either FBG≥7.0 mmol/L or HbA1c≥6.5%. We used the Cox proportional hazard regression model to evaluate the association between BMI and the prediction of incident DM. …”
Get full text

Application of Statistical Methods for the Characterization of Radon Distribution in Indoor Environments: A Case Study in Lima, Peru by Rafael Liza, Félix Díaz, Patrizia Pereyra, Daniel Palacios, Nhell Cerna, Luis Curo, Max Riva

“…Non-normally distributed data were normalized using a Box–Cox transformation to improve statistical assumptions, enabling subsequent geostatistical analyses. …”
Get full text

IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery by Cheng H, Ma J, Zhao F, Liu Y, Wu J, Wu T, Li H, Zhang B, Liu H, Fu J, He H, Zhu C, Ren H, Yang C, Qin S

“…The predictive significance of the IINS and CALLY index was evaluated through Kaplan–Meier survival curves and univariate and multivariate Cox regression analyses. Predictive capabilities of the IINS and CALLY index were compared utilizing receiver operating characteristic (ROC) curve analysis, time-dependent ROC curve analysis, and decision curve analysis (DCA). …”
Get full text

Pre-CCRT 18-fluorodeoxyglucose PET-CT improves survival in patients with advanced stages p16-negative oropharyngeal squamous cell carcinoma via accurate radiation treatment plannin... by Tsung-Ming Chen, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Szu-Yuan Wu

“…According to multivariable Cox regression analysis, pre-CCRT 18FDG PET–CT was not a significant prognostic factor for overall survival in patients with stages I–II of p16-negative OPSCC receiving standard CCRT. …”
Get full text

Pembrolizumab hybrid dosing is non-inferior to flat dosing in advanced non-small cell lung cancer: a real-world, retrospective bicenter cohort study by Egbert F Smit, Willemijn S M E Theelen, Michiel M Smeenk, Vincent van der Noort, Jeroen M A Hendrikx, Hanieh Abedian Kalkhoran

“…Overall survival (OS) and progression-free survival (PFS) were assessed by Kaplan-Meier estimation, compared by log-rank test and HRs were calculated with the Cox proportional hazards model in both unweighted and inverse probability of treatment weighted (IPTW) cohorts. …”
Get full text