Monkeypox and other orthopoxvirus zoonoses by K. N. Gruzdev

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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

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Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism by Sergei N. Shchelkunov

“…Here, study of the orthopoxviruses pathogenic for humans, such as variola (smallpox), monkeypox, cowpox, and vaccinia viruses, may be most important. …”
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Pathogen community composition and co-infection patterns in a wild community of rodents by Abbate, Jessica L., Galan, Maxime, Razzauti, Maria, Sironen, Tarja, Voutilainen, Liina, Henttonen, Heikki, Gasqui, Patrick, Cosson, Jean-François, Charbonnel, Nathalie

“…Rodents were screened for virus exposure (hantaviruses, cowpox virus, Lymphocytic choriomeningitis virus, Tick-borne encephalitis virus) using antibody assays. …”
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Monkeypox: a re-emergent virus with global health implications – a comprehensive review by Nourhan G. Naga, Enas A. Nawar, A’laa A. Mobarak, Aya G. Faramawy, Hend M. H. Al-Kordy

“…Abstract Monkeypox virus (MPXV) is an enclosed, double-stranded DNA virus from the Orthopoxvirus genus, which also contains variola, vaccinia, and cowpox. MPXV, which was once confined to West and Central Africa, has recently had a rebound, spreading beyond its original range since 2017. …”
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Mpox gastrointestinal manifestations: a systematic review by Rahul Ramakrishnan, Atira Shenoy, Ranganathan Madhavan, Damon Meyer

“…Other well-known viruses of the Orthopoxvirus genus include the variola virus (smallpox), cowpox virus and vaccinia virus. Although there is a plethora of research regarding the dermatological and influenza-like symptoms of mpox, particularly following the 2022 mpox outbreak, more research is needed on the gastrointestinal (GI) effects.Objectives This systematic review is to outline the GI manifestations of the monkeypox virus.Methods The authors conducted this systematic review using guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. …”
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Smallpox vaccination in a mouse model by S. N. Shchelkunov, A. A. Sergeev, S. A. Pyankov, K. A. Titova, S. N. Yakubitskiy

“…In order to assess the level of the elicited protective immunity, mice were intranasally infected with a highly lethal dose of the cowpox virus on 62 dpi. The results demonstrated that i.d. injection ensures a stronger protective immunity in mice compared to s.s. inoculation for both VACV variants.…”
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Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein by Ai Xiangjun, Zhang Xinlan, Xu Ye, Tan Chufan, Tan Chufan, Duan Chen, Liao Nami, Liu Junxi, Qiu Yilan, Qiu Yilan, Hou Defu, Hou Defu, Wang Qinglin, Wang Qinglin, Liu Rushi, Liu Rushi

“…The coding sequences of the MPXV A29 protein, Cowpox virus (CPXV) 163 protein homolog and Vaccinia virus (VACV) A27 protein homolog were chemically synthesized, and all three recombinant proteins were expressed in Escherichia coli (BL21 Star). …”
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Genome stability of the vaccine strain VAC∆6 by R. A. Maksyutov, S. N. Yakubitskiy, I. V. Kolosova, T. V. Tregubchak, A. N. Shvalov, E. V. Gavrilova, S. N. Shchelkunov

“…Therefore, the risk of spreading zoonotic human orthopoxvirus infections caused by monkeypox and cowpox viruses has increased in the world. First-generation smallpox vaccines based on Vaccinia virus (VAC) are reactogenic and therefore not suitable for mass vaccination under current conditions. …”
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