Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…The combination of the RWQWRWQWR sequence with short anticancer peptides and cell-penetrating peptides allowed the creation of hybrid peptides with improved cytotoxic potency against cervical cancer. Hybrid peptides constitute a novel, viable, and useful strategy for the design and identification of peptide drugs with anticancer activity.…”
Get full text

The bacterial microbiome of symbiotic and menthol-bleached polyps of long-term aquarium-reared Galaxea fascicularis by Puntin, Giulia, Wong, Jane C. Y., Röthig, Till, Baker, David M., Sweet, Michael, Ziegler, Maren

“…They exist as metaorganisms (holobionts), constituted by the association between the (coral) animal host, its obligate endosymbiotic algae (Symbiodiniaceae), and other microorganisms comprising bacteria, viruses, archaea, fungi and other protists. …”
Get full text

Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

“…Conclusions SWGA approach implemented here provides a powerful tool for enhancing genomic analysis of these neglected parasites, revealing population diversity, drug resistance markers, and hypervariable regions. This methodology constitutes a transformative tool to surmount the challenges of genomic analysis for neglected malaria parasites and can improve malaria research and control.…”
Get full text

Integrating microplastic research in sustainable agriculture: Challenges and future directions for food production by Marcelo Illanes, María-Trinidad Toro, Mauricio Schoebitz, Nelson Zapata, Diego A. Moreno, María Dolores López-Belchí

“…As the prevalence of MPs in the environment continues to escalate, policymakers should address the potential risks these contaminants constitute to food safety and agricultural sustainability. …”
Get full text

Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker by Mariana Papalia, Rocio Stucchi, Valeria Alexander, Liliana Clara, Mariángeles Visus, Gabriel Gutkind, Marcela Radice

“…The new OXA variant identified, OXA-1238, could constitute a useful molecular marker for species identification.…”
Get full text

Domestication of different varieties in the cheese-making fungus Geotrichum candidum by Bennetot, Bastien, Vernadet, Jean-Philippe, Perkins, Vincent, Hautefeuille, Sophie, Rodríguez de la Vega, Ricardo C., O’Donnell, Samuel, Snirc, Alodie, Grondin, Cécile, Lessard, Marie-Hélène, Peron, Anne-Claire, Labrie, Steve, Landaud, Sophie, Giraud, Tatiana, Ropars, Jeanne

“…Commercial starter strains were scattered across the cheese clade, thus not constituting a single clonal lineage. The cheese populations were phenotypically differentiated from other populations, with a slower growth on all media, even cheese, a prominent production of typical cheese volatiles and a lower proteolytic activity. …”
Get full text

Extracellular electron shuttles induced transformation and mobilization of Fe/As with the occurrence of biogenic vivianite by Jia Wang, Mengna Chen, Yalong Li, Yang Yang, Zuoming Xie

“…Microorganisms that utilize organic matter to reduce Fe oxides/hydroxides constitute the primary geochemical processes controlling the formation of high-arsenic (As) groundwater. …”
Get full text

Antimicrobial Susceptibility of <i>Salmonella typhi</i> and <i>paratyphi</i> among Pediatric Population at Tertiary Care Center of North Delhi: A Retrospective Study by Shekhar Biswas, Sulagna Tripathy, Arvind Kumar, Sanjay Chattree

“…The median age of patients was 8 years with male and female patients constituting 61.4 and 38.5%, respectively. The disease was prevalent throughout the year with high prevalence between March and May. …”
Get full text

Tectonometamorphic evolution of a subduction plate interface at the base of the Mirdita Ophiolite (Bajram Curri, northeastern Albania) by Madeline Richter, Kilian Pollok, Kujtim Onuzi, Kamil Ustaszewski

“…The assembly of obducted mantle rocks and metamorphic sole constitutes a plate interface that formed during the intraoceanic subduction stage preceding obduction; we call this a fossil intraoceanic plate interface in this paper. …”
Get full text

Most diverse, most neglected: weevils (Coleoptera: Curculionoidea) are ubiquitous specialized brood-site pollinators of tropical flora by Haran, Julien, Kergoat, Gael J., de Medeiros, Bruno A. S.

“…As such, weevil pollinators constitute a relevant model to explore the emergence and evolution of specialized brood-site pollination systems in the tropics. …”
Get full text

Incidence of methicillin, inducible clindamycin, and vancomycin resistance in Staphylococcus aureus clinical isolates in Gombe, Northeastern Nigeria by Haruna Adamu, Celestina T. Otegwu, Fatima B. Abdullahi, Babajide A. Tytler, Busayo O. Olayinka

“…A total of 54.6 % of the isolates were constitutive clindamycin resistant whereas 6.1 % were inducible clindamycin resistant. …”
Get full text

Assessment of Healthcare Solid Waste Composition, Generation and its Management: the case of Two Hospitals of Shashemene Town, Oromia Regional State, Ethiopia by Gudeta Elie, Daniel Fitamo, Semere Gebreaegawi

“…Of the total solid waste generated, over half(GH: 53.3%; PH: 57.1%) constituted general waste (GW), and the remaining (GH: 46.7%; PH: 42.9%) comprised hazardous waste (HW), which exceeded the WHO threshold(10‒25%) intimates the lack of poor waste segregation. …”
Get full text

Clinical Characteristics of Inpatients with Diabetic Foot Ulcer Admitted with Non-Ulcer Complaints: A Retrospective Study by Li L, Li Y, Qin S, Zeng J, Ma W, Wei D

“…Lan Li,1,2 Yue Li,2,3 Shuang Qin,2 Jing Zeng,2 Wanxia Ma,2 Dong Wei2 1Medical Examination Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 2Department of Endocrinology and Metabolism, Diabetic Foot Care Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 3Department of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People’s Republic of ChinaCorrespondence: Dong Wei, Department of Endocrinology and Metabolism, Diabetic Foot Care Center, The Chengdu Second People’s Hospital, Chengdu, Sichuan, 610017, People’s Republic of China, Tel/Fax +86 02867830801, Email weidong314@126.comBackground: Diabetic foot ulcer (DFU) inpatients admitted with non-ulcer complaints constitute a neglected group that might suffer from more non-standard treatments. …”
Get full text

Sub-seasonal Patterns of PM10 and Black Carbon in a Coastal City: A Case Study of Salé, Morocco by Anas Otmani, Abdeslam Lachhab, Abdelfettah Benchrif, Mounia Tahri, Mohamed Azougagh, Mohammed El Bouch, El Mahjoub Chakir

“…Particularly, BC10 constituted roughly 16 ± 6% of PM10 mass. PM10 levels peaked in autumn and winter, with an examination of the possible impact of the COVID-19 pandemic on PM10 fluctuations. …”
Get full text

Effects of a 12-Week Skipping Exercise Program on Leg Endurance in Competitive Badminton Players: A Randomized Controlled Trial by Ririn Irena, Ardila Melati, Vlad Adrian Geanta, ⁠Ayu Mayzura Simbolon, Retha Foret

“…These results indicate that skipping exercises constitute an effective, versatile, and sport-specific training approach for enhancing physical readiness in badminton. …”
Get full text

Militancia, destrucción y resistencias de las mujeres en la Unión Patriótica by Carlos Andrés Torres Mateus

“…On this basis, it divides the destruction of the UP into genocidal cycles and analyses gendered practices by resorting to a broad interpretation of genocide, away from the location of the state as the sole actor, exposing a range of sectors that constituted the perpetrator bloc and that constantly (re)organized themselves to destroy women’s socio-political work. …”
Get full text

Assessment of factors predicting the nutritional status of geriatric people in Tabuk, Saudi Arabia by Samar Lafi Aljohani

“…The age of almost half of them (49.2%) ranged between 60 and 69 years, and males constituted 56.4% of them. Overall, 17.3% of the participants were malnourished, whereas 41.4% were at risk of malnutrition. …”
Get full text

Effectiveness of a pharmacist-led tele-psychiatric clinic in managing drug-related problems by Majed Al Shakhori, Savera Arain, Suhaj Abdulsalim, Mohammed Salim Karattuthodi, Marwa Al Dhamen, Shoruq Almutairi, Shabeer Ali Thorakkattil, Dina Alahmdi, Vijayanarayana Kunhikatta, Abdul Sammad AlJishi

“…Noteworthy interventions also encompassed the identification and management of potential or suspected adverse reactions, comprising 12.35% of the interventions, along with interventions addressing concerns regarding potentially ineffective therapy, which constituted 11.59%.Conclusion: The study underscores the critical role of pharmacists in psychiatric care, with high physician acceptance of their interventions. …”
Get full text

Perception of phage therapy and research across selected professional and social groups in Poland by Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki

“…To the best of our knowledge, with 1,098 collected questionnaires, this article constitutes the first large-scale analysis on phage therapy perceptions, interest and knowledge among ordinary people in a country with a long, internationally recognized, tradition of treating patients with phages. …”
Get full text

Verbascoside Inhibits the Activation of NLRP3 Inflammasome and Improves BV-2 Cell Inflammatory Damage by Wenjing HUANG, Fang CHENG, Min DU, Jiayi CHEN, Wei XIANG, Ke SHI, Xingliang XIE, Yanmei SHENG

“…Conclusion: VB can ameliorate OGD-induced inflammatory damage in BV-2 cells, which may constitute the primary pharmacodynamic basis for the anti-inflammatory effects of OEE. …”
Get full text