Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap... by Weiming Liang, Weiming Liang, Zhijing Wang, Zhilong Huang, Yanping Huang, Chunyan Li, Yiwen Liang, Miaoyan Huang, Duo Zhang, Chenchen Li

“…ObjectiveTo evaluate the efficacy and safety of programmed cell death protein 1 or its ligand (PD-1/L1) inhibitors as first-line therapy in advanced or metastatic urothelial carcinoma (mUC) who are ineligible for platinum-based chemotherapy.MethodA systematic search was conducted in four databases (Pubmed, Embase, Web of Science, and the Cochrane Library) to find articles that evaluate the effectiveness of first-line PD-1/L1 inhibitors for mUC, from the establishment of the databases to 22 November 2023. …”
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Hubungan Electronic Customer Relationship Management (E-Crm) Terhadap Loyalitas Pasien Di Rumah Sakit: Tinjauan Pustaka by Sabrina Aulia Rahma, Holipah Holipah, Harun Al Rasyid, Fida Rahmayanti

“…Based on the literature study conducted, it was found that E-CRM as a strategy to maintain hospital-patient relationships was influenced by several factors such as organizational factors, facilities, and the environment. …”
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Analysis of the Spatial Pattern of Military River Defense on the Ming Great Wall: A Case Study of the Shanxi Section of the Yellow River by Tianlian WANG, Zhe LI

“…MethodsThe quantitative analysis is conducted using the ArcGIS geographic information platform, involving the review of historical documents, the field investigation of existing sites, the utilization of drones for low-altitude image data collection for purpose of generating 3D real scene model, and the integration of historical aerial films and other multi-source data.The specific methodology comprises two key components: Firstly, analyzing the constituent elements of the defense system of river defence space and summarizing their functional attributes based on the theoretical framework of the Ming Great Wall’s military defence; secondly, summarizing the spatial distribution characteristics of river defence elements by incorporating changes in geographic location, hydrology, environment, and other natural factors. …”
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Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atro... by Lin Lin, Tingxuan Huang, Lizhi Li, Yang Lin, Feng Chen, Ziyi Zheng, Jie Zhou, Yizhe Wang, Weihao You, Yujie Duan, Yawen An, Shiwei He, Weimin Ye

“…Gene set score analysis was conducted to compare the functional roles of different fibroblast subtypes and functional changes in cell subtypes between the CAG and control groups. …”
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Kombinasi Intent Classification dan Named Entity Recognition pada Data Berbahasa Indonesia dengan Metode Dual Intent and Entity Transformer by Zahra Asma Annisa, Rizal Setya Perdana, Putra Pandu Adikara

“…To overcome this problem, intent and NER classification can be combined using a multi-task learning mechanism in the form of a Dual Intent and Entity Transformer (DIET) model. The research was conducted by utilizing secondary data from Helpdesk TIK UB, designing DIET models using PyTorch and Transformers libraries, then evaluating DIET models using f1-score. …”
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Visualisasi Data Kriminal Wilayah Polres Musi Banyuasin by Fitri Purwaningtias, Muhamad Ariandi, Maria Ulfa

“…The research method in this study is a descriptive method which analyzes the data collected based on observations and interviews that have been conducted with the employees of the Sat Tahti Polres MuBa. …”
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EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…Additional in vivo and in vitro experiments, including CCK-8 assays, colony formation and mouse xenograft models, were conducted to explore the biological role of NAT10-mediated ac4C modifications. …”
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Intrathecal Clonidine versus Dexmedetomidine as Adjuvants to Hyperbaric Ropivacaine in Lower Limb Orthopaedic Surgeries: A Randomised Clinical Study by Priya Kishnani, Aiman Monaf, Kalpesh Pati, Jatin Patel, Sara Mary Thomas

“…Materials and Methods: This randomised clinical study was conducted in a teritary care facility at the Operation Theatre (OT) complex in the Department of Anaesthesiology at Dhiraj Hospital, Smt. …”
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PENERAPAN PROJECT BASED LEARNING MODEL UNTUK MENINGKATKAN SIKAP ILMIAH MAHASISWA DALAM RANGKA MENGHADAPI ERA MERDEKA BELAJAR by Andik Purwanto, Desy Hanisa Putri, Dedy Hamdani

“…This study aims to improve the scientific attitude and learning outcomes of Physics Education Study Program students, FKIP-UNIB in the Thermodynamics course through the application of the Project Based Learning Model. The research was conducted with classroom action research (PTK) which was carried out in several cycles. …”
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Effect of Rifaximin and a Multi-Strain Probiotic on the Intestinal Microbiome and Cardiovascular Risk Indicators in Patients with Coronary Heart Disease by E. A. Kashukh, E. A. Poluektova, A. V. Kudryavtseva, G. S. Krasnov, V. I. Kazey, P. D. Sobolev, P. V. Gremyakova, V. T. Ivashkin

“…To assess the effect of rifaximin and a multi-strain probiotic on the intestinal microbiome and the indicators of cardiovascular risk in patients with coronary heart disease (CHD).Materials and methods. A study conducted during the 2016–2019 period included 120 people over 50 years old divided into 3 groups. …”
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Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Inter... by Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

“…A structured risk assessment was conducted, followed by a 6-minute walking test and a 37-minute supervised interval session. …”
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Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache by Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

“…Methods This single-centre, retrospective observational study was conducted at a tertiary referral centre specialising in SIH and CSF dynamics disorders. …”
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Review and Prospect of Research on Urban Walking Safety and Environmental Influencing Factors Thereof by Lin LI, Yu YE, Yong CHEN

“…In future research, it is necessary to conduct collaborative thinking on walking safety and pedestrian safety perception, promote the applicability of relevant research technologies, and pay attention to the influence of the development of emerging transportation technologies on the safety quality of walking environment.…”
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Designing a Model for Implementing Digital Banking Policy Based on Using Big Data in Iranian Banking Industry by Rahmatollah Gholipour Souteh, Hamed Esmaeili Rad

“…To this end, semi-structured interviews were conducted with experts in the fields of banking and financial technology. …”
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Analisis Kepuasan Pengguna Aplikasi Sidawai Menggunakan End User Computing Statisfaction (EUCS) DAn Importance Performance Analysis (IPA) by Kiki Haerani, Khairul Imtihan, Wafiah Murniati

“…The quality of information on a system can have a big influence on the level of user satisfaction, and the objectives of using the system can be achieved when the system is used. Research was conducted to determine the level of user satisfaction and the level of gap between expectations and application performance. …”
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Father’s Perceptions of their Role and Involvement in the Family: A Qualitative Study in a Colombian Sample / Percepciones del padre sobre su rol e involucramiento en la familia: u... by Sonia Carrillo, Milton E. Bermúdez, Liliana Suárez, María Camila Gutiérrez, Ximena Delgado

“…The study used a qualitative methodology, one-hour in depth interviews were conducted with the participants. Results indicated important changes in the role of fathers and mothers in Colombian families. …”
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Emerging burden of post-cancer therapy complications on unplanned hospitalisation and costs among Australian cancer patients: a retrospective cohort study over 14 years by Rashidul Alam Mahumud, Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Sabuj Kanti Mistry, Kamrun Nahar Koly, Sujana Haque Chowdhury, Andre M. N. Renzaho, Jeff Gow, Khorshed Alam, Olivia Wawryk

“…A retrospective cohort study was conducted among 8,633 cancer patients (1.03 million emergency hospital admissions) in Victoria, Australia from July 2006 to June 2020, from the Australian healthcare system perspective. …”
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Key prognostic risk factors linked to poor functional outcomes in cerebral venous sinus thrombosis: a systematic review and meta-analysis by Lili Lin, Senfeng Liu, Wei Wang, Xiao-kuo He, Muhammad Hibatullah Romli, Ruthpackiavathy Rajen Durai

“…Methods A systematic review was conducted to explore all prognostic risk factors in studies published from the initial to June 2024 among 5 Databases included PubMed / Medline, Scopus, EBSCOhost, Web of Science, and Cochran Library. …”
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Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children by Naomi Anderson, Sarah F. Brennan, Fiona Lavelle, Sarah E. Moore, Dilara Olgacher, Amy Junkin, Moira Dean, Michelle C. McKinley, Patrick McCole, Ruth F. Hunter, Laura Dunne, Niamh E. O’Connell, Chris T. Elliott, Danielle McCarthy, Jayne V. Woodside

“…The purpose of this study was to conduct a process evaluation to evaluate DAIRE implementation, mechanisms of impact (MOI) and context to elucidate trial results, and inform scalable implementation of the DAIRE approach for successful future rollout. …”
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Analyzing power errors in the optical pumping system of atomic spin comagnetometers by Jiale QUAN, Ye LIU, Longyan MA, Wenfeng FAN, Wei QUAN

“…This model is an important step toward understanding how power errors propagate within a comagnetometer. An experiment was conducted to validate the derived frequency response model, where a sinusoidal wave with a peak power of 2 milliwatts was superimposed on a base pumping power of 35 milliwatts. …”
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