Primary Terminal Haemochromatosis in a 50 Year-Old Patient by M. I. Gonik, M. S. Zharkova, O. Yu. Kiseleva, E. V. Berezina, Sh. A. Ondos, Yu. V. Lerner, E. A. Kogan, V. T. Ivashkin

“…Cardiac rhythm and conduction disorder: paroxysmal atrial fibrillation. …”
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Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients by Maryam Shafaati, Abbas Shakoori Farahani, Mohammadreza Salehi, Mohammad Arabzadeh, Helya Bolouki Azari, Arman Soleimany, Maryam Edalatifard, Vahid Salimi, Alireza Abdollahi

“…Methods From December 21, 2022, to May 20, 2023, we conducted a cross-sectional study on hospitalized adults having positive RT-PCR results for RSV. …”
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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Furthermore, gene set enrichment analysis, immune infiltration analysis and correlation analysis with metabolic pathways were conducted, as well as construction of a regulator network and molecular docking. …”
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Dietary supplementation of Astragalus polysaccharide or its nanoparticles enhances testicular hemodynamics, echotexture, scrotal circumference, concentration of testosterone, estra... by Eman Fayez, Ali Salama, Mohamed Ahmed Ismail, Fady Sayed Youssef, Zaher Mohamed Rawash, MR Oshba, Haney Samir

“…Blood collection and ultrasonographic assessment of the testes and supratesticular arteries (STAs) were conducted immediately before treatment (W0) and once weekly for 6 successive weeks after APS and nano APS administration (W1-W6). …”
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The Role of School Management Committee and Pupils' Performance in Government Primary Schools in RuhiJa Town Council Rubanda District. by Niwagaba, Alex

“…Participation of School Management Committee members in meetings was one of the ways through which pieces of advice would be provided to the school stakeholders including teachers, learners, head teachers, casual labourers all aimed at shooting in a direction of uplifting the pupils' academic performance (Lamb, 2007). The study was conducted aimed to investigating the role of school management committee on pupils' performance in primary schools in Ruhija Town Council Rubanda District. …”
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Assessing the Factors Influencing Attrition of Health Workers in Government Health Units in Lyantonde District, Uganda. by Kansiime, Benon

“…Methodology Across sectional study of collecting qualitative and quantitative data was conducted on 171 study participants including health workers, Chief Administrative Officer, the District Health Officer, the District Principal Human Resource Officer, Secretary District Service Commission, the Chairperson District Service Commission, the District Principal Internal Auditor, and Secretary for Health, Medical superintendent Lyantonde Hospital, District Planner and the Chief Finance Officer. …”
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Adverse Maternal Outcomes and Associated Factors Among Mothers of Advanced Age delivering at a Tertiary Hospital, Southwestern Uganda: A Cross-Sectional Study. by Masembe, Sezalio, Migisha, Richard, Turyasingura, Godwin, Aheisibwe, Hillary, Nzabandora, Emmanuel, Lule, John C.

“…We determined the prevalence of adverse maternal outcomes and associated factors among mothers of advanced age who delivered at Kabale Regional Referral Hospital (KRRH), in Southwestern Uganda. Methods. We conducted a cross-sectional study at the Maternity Ward of KRRH from April to September 2023. …”
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Prevalence of and Risk factors associated with hypertension: a community based- cross sectional study in Ndorwa West Health Sub District, Kabale district, southwestern Uganda. by Munezero,Tamu John Bosco, Mfitumukiza, Valence, Okafor, Christiana Nkiru, Mandera, Immaculate, Kabami, Jane, Arineitwe, Edward Bwengye, Namuyibwa, Lydia, Izo, Herbert, Baikaitwoha, Everd M., Okonkwo, Uchenna Prosper

“…A community-based cross-sectional survey was conducted with 381 adults aged 25–65 years in Ndorwa West HSD, using a modified WHO STEPwise approach to chronic disease risk factor surveillance. …”
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Temporal Changes in Plasmodium Falciparum Genetic Diversity and Multiplicity of Infection Across Three Areas of Varying Malaria Transmission Intensities in Uganda. by Mwesigwa, Alex, Kiwuwa, Steven M., Musinguzi, Benson, Kawalya, Hakiim, Katumba, James Davis, Baguma, Andrew, Mutuku, Irene M., Adebayo, Ismail Abiola, Nsobya, Samuel L., Byakika‐Kibwika, Pauline, Kalyango, Joan N., Karamagi, Charles, Nankabirwa, Joaniter I.

“…Methods: A total of 220 P. falciparum-positive dried blood spot (DBS) filter paper samples from participants in a study conducted during 2011–2012 and 2015–2016 were analyzed. …”
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Modelling and Analysis of Bioretention Systems for Removal of Stormwater Pollutants by Nuwagaba, Emmanuel, Abdulkadir, Taofeeq Sholagberu, Agwe, Michael Tobby, Philip, Tibenderana, Ako, Terseer, Moses N., Twesigye-omwe

“…The parameters tested were Temperature, pH, Electrical Conductivity (EC), Total Dissolved Solids (TDS), Total Coliforms (TC), Faecal Coliforms (FC), Total Suspended Solids (TSS), Biochemical Oxygen Demand (BOD) and Oil & Grease (OG)The results of the study showed that the bio retention model drastically improved storm water quality by reducing values of EC, TDS, TC, FC, TSS, BOD and OG as compared to the tested raw storm water samples. …”
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Consumption of Raw Herbal Medicines Is Associated with Major Public Health Risks amongst Ugandans by Fred, Ssempijja, Keneth Iceland, Kasozi, Ejike, Daniel Eze, Andrew, Tamale, Sylvia Anurika, Ewuzie, Kevin, Matama, Justine, Ekou, Paul, Bogere, Regan, Mujinya, Grace Henry, Musoke, Jovile Kasande, Atusiimirwe, Gerald, Zirintunda, Muhamudu, Kalange, Joel, Lyada, Ritah, Kiconco, Theophilus, Pius, Christopher, Nandala, Roland Mugisha, Kamugisha, Yunusu, Hamira, Edgar Mario, Fernandez, Simon Peter, Musinguzi

“…In Uganda, Vernonia amygdalina is of interest in rural communities due to its therapeutical action on both bacterial and protozoal parasites, however no studies have been conducted to assess the heavy metal concentrations in traditional plants used in alternative medicine. …”
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Misconceptions on COVID-19 Risk Among Ugandan Men: Results From a Rapid Exploratory Survey, April 2020 by Keneth Iceland, Kasozi, MacLeod, Ewan, Ssempijja, Fred, Mahero, Michael W., Matama, Kevin, Musoke, Grace Henry, Bardosh, Kevin, Ssebuufu, Robinson, Wakoko-Studstil, Florence, Echoru, Isaac, Tiyo Ayikobua, Emmanuel, Mujinya, Regan, Nambuya, Grace, Onohuean, Hope, Zirintunda, Gerald, Ekou, Justine, Welburn, Susan Christina

“…Methods: A cross-sectional survey carried out in early April 2020 was conducted with 161 Ugandans, who purposively participated in the online questionnaire that assessed understandings of COVID-19 risk and infection. …”
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Out-of-Pocket Expenditure (OOPE) on Selected Surgeries in the Obstetrics and Gynaecology Department incurred by Ayushman Bharat Pradhan Mantri Jan Arogya  Yojana (AB-PMJAY), Privat... by Dr. Kumar Sumit, Reena Verma, Prajwal Salins, Helmut Brand, Siddhartha Sankar Acharya, Sagarika Kamath, rajesh kamath, Dr. Vidya Prabhu

“…Methodology A retrospective study was conducted at a tertiary care teaching hospital in Karnataka state of India to analyze OOPE for 905 OBG patients who underwent Cesarean Section(C-Section), Laparoscopic Hysterectomy, Laparoscopic Cystectomy, Laparoscopic Myomectomy and Laparoscopic Assisted Vaginal Hysterectomy (LAVH). …”
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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context by Hui Ying, Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen, Min Xu, Tiange Wang, Mian Li, Zhiyun Zhao, Ruizhi Zheng, Shuangyuan Wang, Hong Lin, Yu Xu, Jieli Lu, Weiqing Wang, Guang Ning, Jie Zheng, Yufang Bi

“…Limited effective immune-mediated antiviral drugs have been launched. Methods: We conducted a Mendelian randomization (MR) and colocalization analysis using 26,597 single-cell expression quantitative trait loci (sc-eQTL) to proxy effects of expressions of 16,597 genes in 14 peripheral blood immune cells and tested them against four COVID-19 outcomes from COVID-19 Genetic Housing Initiative GWAS meta-analysis Round 7. …”
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Genome-wide association study of the antibody response to <i>Corynebacterium pseudotuberculosis</i> in sheep by J. Kyselová, L. Tichý, J. Marková, A. Gurgul, Z. Sztankóová, K. Vališ, S. Šlosárková, K. Kavanová, M. Beinhauerová, T. Szmatola, T. Szmatola

“…A case–control GWAS including 143 seropositive and 178 seronegative sheep was conducted to assess the relationship between the sheep genome and the antibody response to a phospholipase D antigen of <i>C. pseudotuberculosis</i> using GCTA software. …”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…Hence, we aimed to develop a predictive biomarker of immunotherapy efficacy through a machine learning analysis of the TIME.Methods We conducted a biomarker analysis in a prospective study of patients with extensive-stage SCLC who received chemoimmunotherapy as the first-line treatment. …”
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CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs by Yu Liang, Shuang Chen, Zhi Chen, Fang Peng, Qianwen Liu, Gan Xiong, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Demeng Chen, Qimin Zhou

“…Moreover, IHC, flow cytometry, and immunofluorescence techniques were employed to measure immune cell proportions in ESCC. In addition, we conducted single-cell RNA sequencing analysis to examine the alterations in tumor microenvironment following CD276 depletion.Results In this study, we elucidate that CD276 is markedly upregulated in ESCC, correlating with poor prognosis. …”
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Effects of nano-selenium and/or vitamin E supplementation on growth performance, antioxidant status, histopathology and resistance to Aspergillus flavus in Nile tilapia (Oreochromi... by Walaa K. Bazina, Wesam A. Tawfik, Nadia A. Abd Elghany, Saadea Saadony, Zulhisyam Abdul Kari, Muna Omer Alamoudi, Mohamed Y. M. Aly, Abuelhassan Elshazly Younis, Roshmon Thomas Mathew, Moaheda E. H. Eissa, Mohammad Bodrul Munir, Saadiah Ibrahim, Ismail Yousef, Yusuf O. H. Omar, El-Sayed Hemdan Eissa, Heba E. Abd Elnabi

“…Results Monosex Nile tilapia fingerlings were sourced from the Bazina farm and hatchery in Ismailia Governorate, Egypt, where the experiment was also conducted. The fish were acclimatized for 15 days before the trial. …”
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Maternal age-related declines in live birth rate following single euploid embryo transfer: a retrospective cohort study by Wei Jiang, Zichen Zheng, Nan Yan, Shuang Yao, Qijun Xie, Danyu Ni, Shanren Cao, Chun Zhao, Xiufeng Ling

“…Methods This retrospective analysis was conducted on 1037 cycles of single euploid embryo transfer performed at Nanjing Women and Children’s Healthcare Hospital between January 2016 and April 2023. …”
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CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct t... by Mercedes Zubiaur, Laura C. Terrón-Camero, Fernando Gordillo-González, Eduardo Andrés-León, Alicia Barroso-del Jesús, Luz María Canet-Antequera, María M. Pérez Sánchez-Cañete, África Martínez-Blanco, Marilú Domínguez-Pantoja, María Botia-Sánchez, Sonia Pérez-Cabrera, Nerea Bello-Iglesias, Antonio Alcina, Ana-Clara Abadía-Molina, Fuencisla Matesanz, Esther Zumaquero, Ramón Merino, Jaime Sancho

“…This study aimed to elucidate the transcriptomic signatures and dysregulated pathways associated with the autoimmune response in Cd38-/- mice compared to wild-type (WT) mice within the bm12 chronic graft-versus-host disease (cGVHD) lupus model. We conducted bulk RNA sequencing on peritoneal exudate cells (PECs) and spleen cells (SPC) at two and four weeks following adoptive cell transfer. …”
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