Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment by Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon

“…However, specific virally-encoded epitopes and their corresponding immune responses are not fully defined.Methods To understand the OPSCC immune landscape, we conducted a comprehensive single-cell analysis of HPV16+ and HPV33+ primary tumors and metastatic lymph nodes. …”
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Clinical symptoms and functional impairment in attention deficit hyperactivity disorder (ADHD) co-morbid tic disorder (TD) patients: a cluster-based investigation by Zhongliang Jiang, Hui Xu, Anyi Zhang, Liping Yu, Xianbin Wang, Wenyan Zhang, Yonghua Cui, Ying Li

“…The number of clusters was determined using the elbow method, and K-means clustering was conducted. Fisher discriminant analysis and silhouette score were used for validation. …”
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Tritordeum, barley landraces and ear photosynthesis are key players in cereal resilience under future extreme drought conditions by Ander Yoldi-Achalandabaso, Aitor Agirresarobe, Artūrs Katamadze, Giulia Burini, Omar Vergara-Díaz, Mariana Mota, Cristina Oliveira, Usue Pérez-López, Rubén Vicente

“…Our study aimed to identify key functional traits and stress-tolerant germplasm to contribute to designing drought-resilient crops under future Mediterranean climatic conditions. For that, we conducted an innovative approach combining a late-sowing field trial with two contrasting water regimes to simulate future extreme drought conditions, the use of high-throughput phenotyping devices and an infrared gas analyser to characterise leaf and ear photosynthesis, biochemistry, growth, and stress responses during the reproductive stage, and a novel linear mixed-effects model to integrate these results with final agronomical data. …”
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Heavy metal and metalloid pollution: A systematic review of health implications for pregnant women, children, and geriatrics in the East African region by Godswill J. Udom, Brian Turyahabwe, Ayodeji Aturamu, Omoirri M. Aziakpono, Richard D. Agbana, Omole G. Joseph, Nita-wills G. Udom, Nuru Mugide, Omali P. Odey, Haron Olot, Orish E. Orisakwe

“…A risk-of-bias assessment was conducted using the Risk-of-bias VISualization (robvis) tool. …”
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Assessing Prevention Protocols by a Brief Questionnaire in the Infectious Respiratory Diseases Pandemics: An Application in Pedestrian Population in COVID-19 Pandemic by Ali Jafari-Khounigh, Alireza Razzaghi, Hamid Sharifi, Shahram Habibzadeh, Seyed Taghi Heydari, Rasool Entezarmahdi, Mostafa Farahbakhsh, Alireza Ansari Moghaddam, Mahdi Rezaei, Mohammad Saadati, Ehsan Sarbazi, Morteza Haghighi, Mina Golestani, Homayoun Sadeghi-Bazargani

“…This cross-sectional study was conducted using convenience sampling method in May and June 2021. …”
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Integration of ground-based and remote sensing data with deep learning algorithms for mapping habitats in Natura 2000 protected oak forests by Lucia Čahojová, Ivan Jarolímek, Barbora Klímová, Michal Kollár, Michaela Michalková, Karol Mikula, Aneta A. Ožvat, Denisa Slabejová, Mária Šibíková

“…Field validation, which was conducted at randomly generated locations within the relevancy map, yielded an accuracy of 98.33%. …”
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Raising awareness of alcohol as a modifiable risk factor for breast cancer: A randomized controlled trial comparing the efficacy of accessing an interactive website with a non-inte... by Claudia Sardu, Fabrizio Angius, Paolo Contu, Sofia Cosentino, Monica Deiana, Matteo Fraschini, Clelia Madeddu, Elena Massa, Alessandra Mereu, Luigi Minerba, Carola Politi, Silvia Puxeddu, Francesco Salis, Julia M.A. Sinclair, Roberta Agabio

“…We aimed at investigating the efficacy of accessing an interactive website in increasing the knowledge that alcohol is a BC risk factor. Methods: We conducted a randomized controlled trial among women waiting for mammography. …”
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A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods by Yajun Qiao, Yajun Qiao, Yajun Qiao, Juan Guo, Qi Xiao, Jianv Wang, Jianv Wang, Xingfang Zhang, Xingfang Zhang, Xinxin Liang, Xinxin Liang, Lixin Wei, Lixin Wei, Hongtao Bi, Tingting Gao, Tingting Gao

“…In this study, chronic restraint stress (CRS) mouse models were used to simulate chronic stress, and behavioral tests were conducted, including the open field test (OFT), tail suspension test (TST) and forced swimming test (FST). …”
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Bibliometric and visual analysis in the field of electroacupuncture’s analgesia and regulation on negative emotion from 2014 to 2024 by Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Junfan Fang, Jianqiao Fang, Jianqiao Fang, Junying Du, Junying Du

“…EA, a contemporary adaptation of traditional acupuncture, has gained significant attention for its potential therapeutic benefits in managing chronic pain and mood disorders.MethodsUsing the Web of Science Core Collection as the primary data source, we identified 537 articles related to EA’s therapeutic effects. The analysis was conducted using bibliometric tools such as VOSviewer and CiteSpace to visualize publication trends, research hotspots, and collaborative networks.ResultsThe study highlights a significant upward trend in research output, with a marked increase in publications from 2019 onwards. …”
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The impact on productivity costs of reducing unemployment in patients with advanced breast cancer: A model estimation based on a Portuguese nationwide observational study by Leonor Vasconcelos de Matos, Margarida Borges, Ana Teresa Oliveira, Carolina Bulhosa, Luís Silva Miguel, Tiago Fidalgo de Freitas, Renato Cunha, Ana Duarte Mendes, Ana Júlia Arede, Cristiana Marques, Diogo Alpuim Costa, Jorge Alves Correia, Margarida Brito, Mário Fontes e Sousa, Teresa Guimarães, Fatima Cardoso

“…The analysis was based on a cumulative incidence model for estimation of ABC prevalence and on a cross-sectional study characterizing the employment status of patients with ABC. This study was conducted in Portuguese hospitals, between Nov2021-Dec2022 and included patients diagnosed with ABC for at least 6 months, aged 66 or less and consenting for a self-answered questionnaire regarding work status. …”
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How much preoperative ROM and FC is a predictor for poor result after total knee arthroplasty in hemophilic arthropathy? by Hongyu Jiang, Hongyu Jiang, Hongyu Jiang, Xueke Chang, Xueke Chang, Fubin Yu, Wei Li, Naihan Fang, Naihan Fang, Jianzhi Man, Jianzhi Man, Kangshu Guo, Kangshu Guo, Hongzheng Meng, Hongzheng Meng, Wenqiang Zhang

“…AimWe aimed to explore the threshold of preoperative range of motion (ROM) and flxion contacture (FC) as a predictor of Poor knee function after TKA.MethodA retrospective analysis was conducted on 84 Patients with haemophilia (PWH) (113 knees) who underwent knee arthroplasty in our hospital from January 2010 to December 2020 (mean follow-up 70.7 ± 22.4 months). …”
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Prevalence and spatial distribution of workplace violence against emergency medical staff in China: a cross-sectional study by Ruofan ZHANG, Jing FENG, Ge QU, Xinyan LI, Zihui LEI, Yuchao SUN, Aoqi SHEN, Chuanzhu LV, Xingyue SONG, Yong GAN

“…MethodsA multi-stage random sampling method was used to conduct a survey of 34 819 ED medical staff in 31 provincial administrative regions in China from July to September 2019. …”
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Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach by Sakhr Alshwayyat, Mahmoud Bashar Abu Al Hawa, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Siya sawan, Ghaith Heilat, Hanan M. Hammouri, Sara Mheid, Batool Al Shweiat, Hamdah Hanifa

“…To identify the prognostic variables, we conducted Cox regression analysis and constructed prognostic models using five Machine Learning (ML) algorithms to predict the 5-year survival. …”
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Survival feature and trend of female breast cancer: A comprehensive review of survival analysis from cancer registration data by Dan-Dan Tang, Zhuo-Jun Ye, Wan-Wan Liu, Jing Wu, Jing-Yu Tan, Yan Zhang, Qun Xu, Yong-Bing Xiang

“…Using PubMed, Embase, Web of Science, SEER, and SinoMed, a comprehensive literature search was conducted for female breast cancer survival from the population-based cancer registries through 31 December 2023. …”
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Optimising subsurface integrity and surface quality in mild steel turning: A multi-objective approach to tool wear and machining parameters by Muhammad Imran, Suo Shuangfu, Bai Yuzhu, Wang Yuming, Naveed Raheel

“…Secondly, an examination was conducted to assess the influence of tool wear on the morphology of the turning surface using the white light interferometer (ZYGO). …”
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Clinical efficacy and safety of proton radiotherapy for ocular conjunctival malignancies: a systematic review and meta-analysis by Tingwei Zheng, Tingwei Zheng, Dandan Wang, Yuxin Miao, Yuxin Miao, Meng Dong, Qin Liu, Qin Liu, Qiuning Zhang, Huiling Bai, Huiling Bai, Hongtao Luo, Meixuan Li

“…ObjectiveThe use of proton beam therapy (PBT) for treating ocular conjunctival malignancies is on the rise across numerous medical centers. This study conducts a systematic review and meta-analysis to assess the effectiveness and safety of PBT in treating malignant conjunctival tumors.MethodsWe searched for studies on PBT for ocular conjunctival malignancies in PubMed, Embase, Cochrane Library, and Web of Science (WoS) databases up to November 25, 2023. …”
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Affective touch enhances low gamma activity during hand proprioceptive perception in children with different neurodevelopmental conditions by Álvaro Sabater-Gárriz, Álvaro Sabater-Gárriz, Álvaro Sabater-Gárriz, Álvaro Sabater-Gárriz, José Antonio Mingorance, José Antonio Mingorance, José Antonio Mingorance, Francesc Mestre-Sansó, Vicent Canals, Yannick Bleyenheuft, Pedro Montoya, Pedro Montoya, Inmaculada Riquelme, Inmaculada Riquelme, Inmaculada Riquelme

“…Time-frequency analysis of low gamma activity (30–45 Hz) on the left somatosensory cortex was conducted for each condition. Proprioceptive performance was assessed through participants’ accuracy in identifying wrist positions. …”
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Frost resistance and micro mechanism of metakaolin and polypropylene fiber modified coastal cement soil by Xukun Ma, Pengfei Wei, Ping Jiang, Haoqing Xu, Na Li, Sijia Qian, Wei Wang, Guoxiong Mei

“…In order to investigate the effects of metakaolin and polypropylene (PP) fiber on the macroscopic mechanical properties and microscopic mechanisms of cement soil subjected to freeze-thaw cycles, a series of unconfined compressive strength (UCS) and splitting tensile strength (STS) tests were conducted on samples with varying dosages of metakaolin and PP fiber. …”
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Development of Cross-Sector Collaboration Indicators for Accelerating the Reduction of Stunting in South Sulawesi, Indonesia by Balqis Balqis, Suci Rahmadani, Muh. Yusri Abadi, St. Rosmanely, Arif Anwar, Laksmi Trisasmita, Ni Made Viantika Sulianderi, Faizal Fahmi, Arsunan Arsin, Muh. Amri Arfandi, Nur Annisa Hamka, Amaliah Amriani. AS

“…In the second phase, quantitative analysis was conducted with 50 respondents to test the developed indicators using Confirmatory factor analysis (CFA) methods. …”
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Search for Neutrino Signals Correlated with LHAASO Diffuse Galactic Emission by Wenlian Li, Tian-Qi Huang, Donglian Xu, Huihai He

“…Using 7 yr of publicly available IceCube track data with the full detector, we conduct a template search using the γ -ray flux map observed by LHAASO-KM2A as the neutrino emission template and perform a scan search of the Galactic plane. …”
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