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29781
Confronting needlestick and sharp injuries in healthcare: a decade of struggle and progress in a university teaching hospital
Published 2025-02-01“…Methods A retrospective analysis was conducted on NSI reports from 2014 to 2023, focusing on episodes involving medical, nursing, allied health, and other staff. …”
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29782
Assessment of Types, Factors Contributing to Violence Against Women and its Effects on the Health Seeking Behaviour of Women in Rubanda Town Council Rubanda District.
Published 2024“…A cross-sectional study collecting qualitative and quantitative data was conducted from 422 study participants, including 407 women, 4 probation officers, 6 police, and 10 Local council chairpersons. …”
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29783
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29784
Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis
Published 2025-01-01“…This study aimed to uncover the essential predictive descriptors governing nanoparticle-induced pulmonary fibrosis. Methods We conducted a comprehensive analysis of the trajectory of metal oxide nanoparticles (MeONPs) within pulmonary systems. …”
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29785
Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13])
Published 2025-01-01“…This pre-specified analysis was conducted to determine whether adjuvant palbociclib benefited patients diagnosed with lower risk stage IIA disease compared to those with higher stage disease. …”
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29786
Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality
Published 2022-06-01“…Methods and results We conducted a retrospective cohort study based on the Medical Information Mart for Intensive Care III (MIMIC‐III) database. …”
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29787
SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial
Published 2025-02-01“…This article outlines the protocol for a randomised clinical trial (RCT) that aims to determine if minimalist footwear improves pain, function and other symptoms compared with motion control shoes, in adolescents with patellofemoral pain.Methods and analysis This is a 3-month, pragmatic, two-arm parallel group, comparative effectiveness, superiority RCT conducted in Melbourne, Australia. We are recruiting 158 participants aged between 12 and 19 years with patellofemoral pain from the community. …”
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29788
Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses
Published 2025-01-01“…This study utilized meta-analysis to evaluate CAR-T-cell therapy efficacy and safety and employed two-sample Mendelian randomization (MR) analysis to investigate the causal links between immune cells and Multiple Myeloma (MM).MethodOur literature review, conducted from January 1, 2019, to August 30, 2024, across Medline/PubMed, Scopus, and Web of Science, identified 2,709 articles, 34 of which met our inclusion criteria. …”
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29789
The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications
Published 2025-02-01“…Additionally, a clonogenic assay was performed to measure tumor cell survival and subsequent proliferative capacity after drug exposure was conducted for the most active extract(s) and finally western blotting was used to determine the expression change of the two selected proteins (survivin and CCND1) in order to determine the exact mechanistic features of the most promising plant extract. …”
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29790
Outcomes of patients after successful left ventricular assist device explantation: a EUROMACS study
Published 2020-06-01“…A Kaplan–Meier analysis for freedom of the composite endpoint of death, heart transplantation, LVAD reimplantion, or heart failure (HF) relapse was conducted. A total of 45 (1.4%) cases with myocardial recovery resulting in successful LVAD explantation were identified. …”
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29791
Artificial intelligence-based prediction of second stage duration in labor: a multicenter retrospective cohort analysisResearch in context
Published 2025-02-01“…Methods: This multicenter, retrospective study was conducted at four tertiary hospitals in China from September 2013 to October 2022. …”
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29792
Urinary System Manifestation of IgG4-Related Disease: Clinical, Laboratory, Radiological, and Pathological Spectra of a Chinese Single-Centre Study
Published 2020-01-01“…Here, we described clinical, radiological, and pathological manifestations of IgG4-related urinary disease (IgG4-RUD) and assess its treatment responses. Methods. We conducted a retrospective study enrolling 65 IgG4-RUD patients from an IgG4-related disease (IgG4-RD) cohort of the Peking Union Medical College Hospital. …”
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29793
Dental and oral health assessments in the German National Cohort (NAKO)
Published 2025-01-01“…In addition, a reliability study was conducted among 794 Level 1 and 359 Level 2 participants, reporting intra class correlation and kappa coefficients. …”
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29794
Assessing the role of genotype by environment interaction of winter wheat cultivars using envirotyping techniques in North China
Published 2025-02-01“…Accurate yield estimation depends on understanding the patterns of GEI in multi-environment trials (METs).MethodsFrom 2014 to 2018, continuous experiments were conducted in the Heilonggang region of the North China Plain (NCP), evaluating 71 winter wheat genotypes across 16 locations over five years. …”
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29795
Associations of dose to the urethra and long-term patient-reported outcomes after radiotherapy with EBRT and HDR brachytherapy boost for prostate cancer
Published 2025-03-01“…Materials and methods: We conducted a pre-registered (https://doi.org/10.17605/OSF.IO/A6DC3) cross-sectional study at a tertiary academic center including a consecutive sample of patients being at least two years after treatment. …”
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29796
LLT1 overexpression renders allogeneic-NK resistance and facilitates the generation of enhanced universal CAR-T cells
Published 2025-01-01“…We performed cytotoxicity, proliferation, and cytokine assays to evaluate the functionality of universal chimeric antigen receptor-T cell (UCAR-T) cells and conducted in vitro and in vivo assays, including allogeneic responses and RNA sequencing, to assess their resistance to allogeneic T and NK cells, anti-leukemia efficacy, and persistence in treating hematologic malignancies. …”
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29797
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
Published 2025-02-01“…In many malaria-endemic areas of Africa, the burden of malaria is largely restricted to the rainy season and, therefore, a recent trial conducted in Burkina Faso and Mali explored the impact of repeated annual booster doses of RTS,S/AS01E given immediately prior to the malaria transmission season until children reached the age of five years. …”
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29798
Mobile Toolbox sequences task: development and validation of a remote, smartphone-based working memory test
Published 2025-01-01“…This study describes the development of Sequences and presents the studies conducted to evaluate its psychometric properties.MethodsWe developed a new measure of working memory that can be self-administered remotely using an iOS or Android smartphone. …”
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29799
Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies
Published 2025-02-01“…So far, most of the research on agroecological animal production systems was conducted at farm scale, and the potential of agroecological principles addressing social dimensions and food system−level approaches has been underexplored. …”
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29800
Evaluation of pitomba extract as a natural antioxidant in fresh sausages: Effects on physicochemical properties and lipid oxidation
Published 2025-03-01“…The sausages were analyzed for pH, water holding capacity (WHC), cooking loss (CWL), lipid oxidation, and objective color (L∗, a∗, b∗, chroma, and hue angle). Analyses were conducted 24 h after production and again on days 7, 11, and 14 of refrigerated storage at 5 °C. …”
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