Severe Psychomotor Delay in a Severe Presentation of Cat-Eye Syndrome by Guillaume Jedraszak, Aline Receveur, Joris Andrieux, Michèle Mathieu-Dramard, Henri Copin, Gilles Morin

“…The use of array comparative genomic hybridization ruled out the involvement of another chromosomal imbalance in the neurological phenotype. …”
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A Rare Prenatal Case: Greig Cephalopolysyndactyly Syndrome by Tilbe Hakçıl, Gülsüm Kayhan, Tuncay Nas, Pınar Telli Celtemen, Meral Yirmibeş Karaoğuz

“…The presence of the short arm terminal region of the relevant chromosome was confirmed by fluorescence in situ hybridization analysis. Array comparative genomic hybridization technique verified the breakpoint regions and revealed a 17.4 Mb deletion covering the GLI3 gene. …”
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Epidemiological and molecular characterization of investigation of Mycoplasma gallisepticum of goose origin in Guangdong (China) by Nan Zhang, Yixin Jia, Weihuo Li, Yangshuo Li, Jingyi Liang, Zhaofeng Yao, Sheng Yuan, Hong Yang, Huanzhong Ding, Yuanyuan Zhou

“…In addition, our research included a comparative genomes analysis of of MG strains from both geese and chickens, and we developed a mgc2 gene typing method. …”
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Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies by J. Kimble Frazer, Lance A. Batchelor, Diana F. Bradley, Kim H. Brown, Kimberly P. Dobrinski, Charles Lee, Nikolaus S. Trede

“…In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Using array comparative genomic hybridization (aCGH), a technique to detect numeric variations between different DNA samples, we examined genomes from zebrafish (Danio rerio) T-cell leukemias of three cancer-prone lines. …”
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Chromosome 15q13.1q13.2 microdeletion in a foetus with severe congenital heart defects: A case report by Thi Ha Vu, Thi Hai Hoang, Thi Sim Nguyen, Khanh Dung Ho, Thi Kim Phuong Doan

“…In a 22-week gestation foetus, severe congenital heart defects were detected by colour Doppler ultrasound imaging. Array comparative genomic hybridisation (aCGH) was performed, revealing a 1.1 Mb deletion of the chromosome 15q13.1-q13.2 region containing five genes (APBA2, NSMCE3, TJP1, FAM189A1, LOC100130111). …”
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Genomic epidemiology and phenotypic characterization of Staphylococcus aureus isolated from atopic dermatitis patients in South China by Chao Yang, Xiaowei Chen, Min Li, Wenchang Yuan, Shunguang Li, Dexing Han, Junhui Feng, Haimin Luo, Minling Zheng, Jiaqi Liang, Cha Chen, Pinghua Qu, Song Li

“…S. aureus of Chinese AD patients was mainly distributed in SC2, SC7, and SC12. Comparative genomic highlighted genes linked to AD, including enterotoxins (seh, selk, selq, entH), adhesion genes (fnbA, fnbB, sdrD, map, fib, narH). …”
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Complete genome sequence of Pseudomonas aeruginosa YK01, a sequence type 16 isolated from a patient with keratitis by Shuo Jiang, Mengmin Ye, Ke Liu, Huiluo Cao, Xiaoshan Lin

“…To our knowledge, this genome data represents the first complete genome of P. aeruginosa ST16, providing crucial information for further comparative genome analysis.…”
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Successful Oocyte Retrieval, Fertilization, and Clinical Pregnancy with Low Serum β-hCG on the Day of Oocyte Collection: A Reappraisal of the Definition of the Empty Follicle Syndr... by Nicole A. Van De Velde, Charalampos Chatzicharalampous, Awoniyi O. Awonuga

“…Of these, eight embryos survived to day 5 and were subjected to preimplantation genetic screening (PGS) by comparative genomic hybridization (CGH). Results were available the next day, three of the embryos were euploid and one was transferred on day 6. …”
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Evaluation of the Effects of Different Bacteroides vulgatus Strains against DSS-Induced Colitis by Sijia Li, Chen Wang, Chengcheng Zhang, Yanhong Luo, Qianqian Cheng, Leilei Yu, Zhen Sun

“…In contrast, B. vulgatus 51K1 significantly worsened the DSS-induced alterations in the tumor necrosis factor-alpha (TNF-α) concentration and colonic histopathology. A comparative genomic analysis of B. vulgatus 7K1 and 51K1 showed that the beneficial effects of B. vulgatus 7K1 may be associated with some of its specific genes involved in the production of short-chain fatty acids or capsular polysaccharides and enhancement of its survivability in the gut. …”
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Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens. by Valentina Del Olmo, Álvaro Redondo-Río, Alicia Benavente García, Savitree Limtong, Ester Saus, Toni Gabaldón

“…Here, we sequenced the genomes of five new C. metapsilosis isolates, one representing the first African isolate for this species, and four environmental isolates from marine niches. Our comparative genomic analyses, including a total of 29 sequenced strains, shed light on the phylogenetic relationships between C. metapsilosis hybrid isolates and show that environmental strains are closely related to clinical ones and belong to different clades, suggesting multiple independent colonisations. …”
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Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts. by Jeffrey Vedanayagam, Ching-Jung Lin, Ranjith Papareddy, Michael Nodine, Alex S Flynt, Jiayu Wen, Eric C Lai

“…The consequences of deleting even a single hpRNA (Nmy) in males are profound, as such individuals are nearly incapable of siring male progeny. Here, comparative genomic analyses of D. simulans and D. melanogaster mutants of the core RNAi factor dcr-2 reveal a substantially expanded network of recently-emerged hpRNA-target interactions in the former species. …”
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De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer <i>Azohydromonas lata</i> Strain H1 Genome and Genomic Analysis of PHB Production Machinery by Daniele Traversa, Carlo Pazzani, Pietro D’Addabbo, Lucia Trisolini, Matteo Chiara, Marta Oliva, Angelo Marzella, Camilla Mandorino, Carla Calia, Guglielmina Chimienti, Caterina Manzari, Graziano Pesole, Maria Scrascia

“…In addition to the <i>phaCAB</i> operon, single genes ascribable to PhaC and PhaA functions and auxiliary genes were also detected. A comparative genomic analysis of the available genomes of the genus <i>Azohydromonas</i> revealed the presence of <i>phaCAB</i> and auxiliary genes in all <i>Azohydromonas</i> species investigated, suggesting that the PHB production is a common feature of the genus. …”
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Ammonifying and phosphorus-solubilizing function of Aliikangiella maris sp. nov. isolated from Phaeocystis globosa bloom and algal–bacterial interactions by Fei Li, Fei Li, Ming-Ben Xu, Liang-Hao Pan, Jie Li, Cai-Bi Lan, Zhe Li, Shan Lu, Jun-Xiang Lai, Jun-Xiang Lai, Peng-Fu Li

“…According to phenotypic, chemotaxonomic, phylogenomic, and comparative genomic analyses data, strains GXAS 306T and GXAS 311 were considered to represent a novel species of the genus Aliikangiella. …”
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Prenatal Identification and Molecular Characterization of Two Simultaneous De Novo Interstitial Duplications of Chromosomal Regions 7p22.1p21.1 and 15q24.1 by Sabrina C. Burn, Kali Swift, Maria Palmquist

“…Cytogenetic analysis of cultured amniocytes by conventional chromosome analysis, comparative genomic hybridization, and fluorescence in situ hybridization revealed two interstitial duplications of the chromosomal regions 7p22.1p21.1 and 15q24.1, leading to partial trisomy of 7p and 15q and karyotype 46,XY,dup(7)(p22.1-p21.1),dup (15)(q24.1). …”
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Multi-omics investigation of high-transglutaminase production mechanisms in Streptomyces mobaraensis and co-culture-enhanced fermentation strategies by Huanan Chang, Ziyu Zheng, Hao Li, Yanqiu Xu, Gengyao Zhen, Yao Zhang, Xidong Ren, Xidong Ren, Xinli Liu, Xinli Liu, Deqiang Zhu, Deqiang Zhu

“…Using this strain as a forward mutation gene pool, comparative genomic research identified 95 mutated genes, which were mostly due to base substitutions that led to changes in codon usage preference. …”
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Clinical Report of a 17q12 Microdeletion with Additionally Unreported Clinical Features by Jennifer L. Roberts, Stephanie K. Gandomi, Melissa Parra, Ira Lu, Chia-Ling Gau, Majed Dasouki, Merlin G. Butler

“…Subsequently, a 400 K array-based comparative genomic hybridization (aCGH) + SNP analysis was performed which identified a de novo suspected pathogenic deletion on chromosome 17q12 encompassing 28 genes. …”
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Evaluation of utilization of amplified blastocoel fluid DNA gel electrophoresis band intensity as an additional minimally invasive approach in embryo selection: A cross-sectional s... by Fattaneh Khajehoseini, Zahra Noormohammadi, Poopak Eftekhari-Yazdi, Hamid Gourabi, Reza Pazhoomand, Shirzad Hosseinishenatal, Masood Bazrgar

“…Materials and Methods: This cross-sectional study categorizes blastocysts into 2 groups based on the array comparative genomic hybridization results by trophectoderm biopsy -the euploid and aneuploid group. …”
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A Biphasic Pleural Tumor with Features of an Epithelioid and Small Cell Mesothelioma: Morphologic and Molecular Findings by Sarah Hackman, Richard D. Hammer, Lester Layfield

“…Fluorescence in situ hybridization testing for the t(11;22)(p13;q12) translocation disclosed loss of the EWSR1 gene in 94% of tumor cell nuclei, but there was no evidence of the classic translocation. Array based-comparative genomic hybridization (a-CGH) confirmed the tumor had numerous chromosome copy number losses, including 11p15.5-p11.12 and 22q12.1-q13.33, with loss of the EWSR1 and WT1 gene regions. …”
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Enhancement of Streptomyces aureoverticillatus HN6 through mutagenesis for improved biocontrol of banana wilt disease: an WGS approach by Xiangnan Yan, Shakil Ahmad, Nazia Manzar, Yunfei Zhang, Coline C. Jaworski, Abhijeet Shankar Kashyap, Lanying Wang, Yanping Luo

“…Moreover, the fermentation broth of the mutant strain E95 substantially improved the bacterial inhibitory activity. Comparative genomic analysis revealed the presence of seven single-nucleotide polymorphisms (SNPs), one multiple nucleotide polymorphism (MNP), and three insertion-deletions when comparing the mutant strain E95 with the original strain HN6. …”
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Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development by Sarah Derks, Cindy Postma, Peter T. M. Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Mario A. J. A. Hermsen, Walter Giaretti, James G. Herman, Matty P. Weijenberg, Adriaan P. de Bruïne, Gerrit A. Meijer, Manon van Engeland

“…Chromosomal alterations were evaluated by comparative genomic hybridization. Results: Our data demonstrate that nonprogressed adenomas, progressed adenomas and carcinomas show similar frequencies of promoter methylation for the majority of the genes. …”
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