Cytogenetic Evolution of Human Ovarian Cell Lines Associated with Chemoresistance and Loss of Tumorigenicity by Stéphanie Struski, Martine Doco‐Fenzy, Michael Koehler, Ilse Chudoba, Francis Levy, Linda Masson, Nicole Michel, Evelyne Ulrich, Nadine Gruson, Jean Bénard, Gérard Potron, Pascale Cornillet‐Lefebvre

“…In order to identify genomic changes associated with a resistant phenotype acquisition, we used comparative genomic hybridization (CGH) to compare a human ovarian cell line, Igrov1, and four derived subcell lines, resistant to vincristine and presenting a reversion of malignant properties. …”
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Screen of propionate-producing probiotic strains in attenuating murine colitis by modulating immune response and restoring the intestinal barrier by Ting Shu, Xizi Song, Silu Zhang, Xiaoli Zhou, Zhizhu Zhang, Pengfei Wang, Hu Canying, Jie Pan, Xiaoshuang Dai, Yan Tan, Wu Xiyang, Huicui Meng, Guoxun Xiao, Huaijie Hao

“…Probiotics produce propionate, a short-chain fatty acid that restores intestinal balance and reduces inflammation.Comparative genomic analysis of propionate pathway integrity was performed to nominate 41 candidate strains. …”
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Comparative analysis of chloroplast genomes reveals molecular evolution and phylogenetic relationships within the Papilionoideae of Fabaceae by Qian Qin, Yanjing Dong, Jialong Chen, Bo Wang, Yuxin Peng, XinPeng Zhang, Xiaoyun Wang, Jinxiang Zeng, Guoyue Zhong, Shouwen Zhang, Xiaolang Du

“…These species exhibit pronounced differences in their non-coding regions. Comparative genomic variations at cpDNA sites were identified. …”
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Whole genome sequencing, assembly and annotation of the Southern Ground Hornbill – Bucorvus leadbeateri by Jasmin Patel, Angela Botes, Jean Mollett, Pieter De Maayer

“…The availability of this genome will aid in improving our current understanding of this bird at a genomic level and provide a pivotal foundation for comparative genomic analysis with other hornbill species.…”
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A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity by Sandra J. Hasstedt, Yuanpei Xin, Rong Mao, Tracey Lewis, Ted D. Adams, Steven C. Hunt

“…CNVs were identified using array comparative genomic hybridization (aCGH) on members of pedigrees ascertained through severely obese (BMI ≥ 35 kg/m2) sib pairs (86 pedigrees) and thin (BMI ≤ 23 kg/m2) probands (3 pedigrees). …”
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Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus by Lixin Zhang, Usha Reddi, Usha Srinivasan, Sheng Li, Stephanie M. Borchardt, Parvathy Pillai, Puja Mehta, Anne N. Styka, Joan DeBusscher, Carl F. Marrs, Betsy Foxman

“…We used microarray-based comparative genomic hybridization to identify open reading frames (ORFs) present in two sequenced invasive strains, but absent or divergent in tester strains. …”
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NMD Microarray Analysis for Rapid Genome-Wide Screen of Mutated Genes in Cancer by Maija Wolf, Henrik Edgren, Aslaug Muggerud, Sami Kilpinen, Pia Huusko, Therese Sørlie, Spyro Mousses, Olli Kallioniemi

“…We combined NMD microarrays with array-based CGH (comparative genomic hybridization) in order to identify inactivation of tumor suppressor genes in cancer. …”
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Telomere-to-telomere Phragmites australis reference genome assembly with a B chromosome provides insights into its evolution and polysaccharide biosynthesis by Jipeng Cui, Rui Wang, Ruoqing Gu, Minghui Chen, Ziyao Wang, Li Li, Jianming Hong, Suxia Cui

“…An explosion of LTR-RTs, centered on the Copia family, occurred during the late Pleistocene, driving the expansion of P. australis genome size and subgenomic differentiation. Comparative genomic analysis showed that P. australis underwent two whole gene duplication events, was segregated from Cleistogenes songorica at 34.6 Mya, and that 41.26% of the gene families underwent expansion. …”
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Mixed Gastric Carcinomas Show Similar Chromosomal Aberrations in Both their Diffuse and Glandular Components by Beatriz Carvalho, Tineke E. Buffart, Rui M. Reis, Thomas Mons, Cátia Moutinho, Paula Silva, Nicole C. T. van Grieken, Heike Grabsch, Cornelis J. H. van de Velde, Bauke Ylstra, Gerrit A. Meijer, Fátima Carneiro

“…In this study, we compared the DNA copy number changes, in the two different components (diffuse and intestinal) of mixed gastric carcinomas by microarray – comparative genomic hybridisation (array CGH). The analysis of 12 mixed gastric carcinomas showed no significant differences in array CGH profiles between the diffuse and intestinal components of mixed carcinomas. …”
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Distinct Chromosomal Profiles in Metastasizing and Non-Metastasizing Colorectal Carcinomas by B. Michael Ghadimi, Marian Grade, Carsten Mönkemeyer, Bettina Kulle, Jochen Gaedcke, Bastian Gunawan, Claus Langer, Torsten Liersch, Heinz Becker

“…Materials and methods: Comparative genomic hybridization (CGH) was used to screen colorectal carcinomas without distant metastases (n=18) and carcinomas synchronously metastatic to the liver (n=18). …”
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Cryptic translocation involving two acrocentric chromosome ends revealed by fluorescence in situ hybridization after two consecutive pregnancies of which the results of chromosome... by Yao-Lung Chang, Hsiu-Huei Peng, Hsueh-Chun Cheng, Chi-Yuan Chiang, Ho-Yen Chueh, Yu-Ting Lin, Chin-Pei Lee, Shuenn-Dyh Chang, Ming Chen

“…Further parental karyotype, parental microarray-based comparative genomic hybridization (array CGH), and fluorescence in situ hybridization (FISH) study were performed to clarify this issue. …”
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Genetic Alterations in Presumptive Precursor Lesions of Breast Carcinomas by Michaela Aubele, Martin Werner, Heinz Höfler

“…In IDH lesions loss of heterozygosity (LOH) at various loci could be identified, and comparative genomic hybridization (CGH) and fluorescence in situhybridization (FISH) studies delivered evidence for DNA amplification on chromosomal region 20q13 in the early stage of IDH. …”
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An Interstitial 20q11.21 Microdeletion Causing Mild Intellectual Disability and Facial Dysmorphisms by Ivan Y. Iourov, Svetlana G. Vorsanova, Oxana S. Kurinnaia, Yuri B. Yurov

“…We report a case of an interstitial chromosome 20q11.21 microdeletion in a 7-year-old male child presenting with mild intellectual disability and facial dysmorphisms. Array comparative genomic hybridization (CGH) has shown that the deletion resulted in the loss of 68 genes, among which 5 genes (COX4I2, MYLK2, ASXL1, DNMT3B, and SNTA1) are disease causing. …”
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Comparative genetic diagnostic evaluation of pediatric neuromuscular diseases in a consanguineous population by Abdullah Al-Hedaithy, Fouad Alghamdi, Momen Almomen, Fawzia Amer, Shaikhah Al Dossari, Deeba Noreen Baig, Shahid Bashir

“…Out of the patients tested, 66% underwent gene panels testing, 56% had Whole Exome Sequencing, 32% received array Comparative Genomic Hybridization (CGH) assays, and 40% underwent metabolic testing. …”
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Stage-specific expression and divergent functions of two insulinase-like proteases associated with host infectivity in Cryptosporidium. by Yue Huang, Shifeng Pei, Xin Lv, Fuxian Yang, Xiaoqing Gong, Na Li, Yaqiong Guo, Yaoyu Feng, Lihua Xiao

“…Results from recent comparative genomic studies suggest that gains and losses of multicopy subtelomeric genes encoding insulinase-like proteases (INS-19 and INS-20 in Cryptosporidium parvum and their orthologs in closely related species) may potentially contribute to these differences.…”
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A chromosome-level genome assembly of the cabbage aphid Brevicoryne brassicae by Jun Wu, Guomeng Li, Zhimou Lin, Yangzhi Zhang, Wenyuan Yu, Rong Hu, Shuai Zhan, Yazhou Chen

“…By integrating high-coverage transcriptome data, we annotated 22,671 protein-coding genes and 3,594 lncRNA genes. Preliminary comparative genomic analyses focused on genes related to host colonization, such as chemosensory- and detoxification-related genes, as well as cross-kingdom lncRNA Ya. …”
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1q21.1 Duplication Syndrome and Anorectal Malformations: A Literature Review and a New Case by Maria Minelli, Chiara Palka Bayard de Volo, Melissa Alfonsi, Serena Capanna, Elisena Morizio, Maria Enrica Miscia, Gabriele Lisi, Liborio Stuppia, Valentina Gatta

“…Case presentation: The present case describes a male, referred to us for an ARM, in whom array—comparative genomic hybridization (array-CGH) identified 1q21.1 duplication inherited from his healthy mother. …”
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High-resolution genetic analysis of whole APC gene deletions: a report of two cases and patient characteristics by Hiroki Tanabe, Yasuyuki Koshizuka, Kazuyuki Tanaka, Kenji Takahashi, Masami Ijiri, Keitaro Takahashi, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Takeo Sarashina, Kentaro Moriichi, Kenrokuro Mitsube, Yusuke Mizukami, Mikihiro Fujiya, Yoshio Makita

“…Recent advances include the use of whole-genome array comparative genomic hybridization (a-CGH), which provides better resolution of genetic imbalances. …”
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A high-quality chromosome-scale genome assembly of the Cherokee rose (Rosa laevigata) by Yi Wang, Huijun Yan, Xianqin Qiu, Hao Zhang, Yonghong Zhang, Hongying Jian

“…The chromosome-scale genome provides valuable information to facilitate comparative genomic analysis of rose family and will accelerate genome-guided breeding and germplasm improvement of both R. laevigata itself and modern roses.…”
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Absence of Substantial Copy Number Differences in a Pair of Monozygotic Twins Discordant for Features of Autism Spectrum Disorder by Marina Laplana, José Luis Royo, Anton Aluja, Ricard López, Damiàn Heine-Sunyer, Joan Fibla

“…Here we present the results of a comparative genome hybridization (CGH) analysis with a pair of monozygotic twins affected of ASD with significant differences in their clinical manifestations that specially affect speech language impairment and communication skills. …”
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