Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats by Jessalyn Pla-Tenorio, Bethzaly Velazquez-Perez, Yainira Mendez-Borrero, Myrella L. Cruz, Marian T. Sepulveda-Orengo, Richard J. Noel

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Corrigendum to “Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait” by M. Rodríguez-Arias, C. Roger-Sánchez, I. Villanova, N. Revert, C. Manzanedo, J. Miñarro, M. A. Aguilar

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Contemporary decongestant practices of Canadian otolaryngologists for endoscopic sinus surgery by Jonathan W. Reid, Brian W. Rotenberg, Leigh J Sowerby

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The Drug-Trafficking Economy and Its Dynamics in Latin America by Daniel Pontón C.

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Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial. by Glenn-Milo Santos, Janet Ikeda, Phillip Coffin, John E Walker, Tim Matheson, Matthew McLaughlin, Jennifer Jain, Eric Vittinghoff, Steven L Batki

“…<h4>Objective</h4>To determine if men who have sex with men (MSM) with cocaine use disorder (CUD) and actively-using cocaine could be enrolled and retained in a pharmacologic intervention trial of lorcaserin-a novel 5-HT2cR agonist-and determine the degree to which participants would adhere to study procedures.…”
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Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes by Dasiel O. Borroto-Escuela, Karolina Wydra, Julia Pintsuk, Manuel Narvaez, Fidel Corrales, Magdalena Zaniewska, Luigi F. Agnati, Rafael Franco, Sergio Tanganelli, Luca Ferraro, Malgorzata Filip, Kjell Fuxe

“…Studies with A2AR ligands using cocaine self-administration procedures indicate that antagonistic allosteric A2AR-D2R heterocomplexes of the ventral striatopallidal GABA antireward pathway play a significant role in reducing cocaine induced reward, motivation, and cocaine seeking. …”
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Electrophysiological properties of melanin-concentrating hormone neuron subpopulations defined by anatomical localization and CART expression by Rafiat Damilola Adekunle, Mohammed Sohel Chowdhury, Lisa Z. Fang, Michiru Hirasawa

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Sociodemographic factors of violent deaths related to licit or ilicit psychoactive substances: a cross-sectional study, Ceará, Brazil, 2015-2019 by Wanderley Pinheiro de Holanda Júnior, Raimunda Hermelinda Maia Maceno, Maria Augusta Drago Ferreira

“…Association was found between benzodiazepines (29.5%) and tricyclic antidepressants (15.6%) and suicides; cocaine (28.1%) and cannabis (27.1%) and homicides; and cocaine (28.2%) and tricyclic antidepressants (5.9%) and suspicious deaths. …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…No illicit drugs were found except cocaine in banknote dust. Its concentration ranged only one order of magnitude, from 2.76E+02 to 4.01E+03 mg of cocaine per gram of banknote dust, in agreement with previous results obtained with methanol as an extractant and organic modifier. …”
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Illicit drug use derived from wastewater-based epidemiology in Iran, their removal during wastewater treatment, and occurrence in receiving waters by Anvar Asadi, Shabnam Zarei, Nebile Daglioglu, Evsen Yavuz Guzel, Neda Ravankhah

“…There was no detection of cocaine, its metabolite benzoylecgonine, or 3,4-methylenedioxymethamphetamine in any of the samples. …”
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Coca: The History and Medical Significance of an Ancient Andean Tradition by Amy Sue Biondich, Jeremy David Joslin

“…Coca is also the whole plant from which cocaine is derived. Coca products are thought to be a panacea for health troubles in regions of South America. …”
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The Main Coronary Artery (LMCA) Thrombus Presented as an ST Elevation Myocardial Infarction in a Hypercoagulable Patient by Nithin Gottam, Douglas Stewart, Hiroshi Yamasaki, Mohamad Ajjour

“…Left main coronary artery (LMCA) thrombus is a clinically rare event and is thought to be secondary to plaque rupture with subsequent thrombus formation, persistent hypercoagulable state, cocaine use, or vasospasm. (Klein et al., 2008) here we present a case of LMCA thrombus that presented as an ST elevation myocardial infarction (STEMI) in a hypercoagulable patient.…”
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Astrocytes Control Neuronal Excitability in the Nucleus Accumbens by Tommaso Fellin, Marcello D'Ascenzo, Philip G. Haydon

“…Though accumulating evidence shows that the metabotropic glutamate receptor 5 (mGluR5) mediates some of the actions of extracellular glutamate after cocaine use, the cellular events underlying this action are poorly understood. …”
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Levamisole-Induced immune phenomenon and its various clinical manifestations in children: Two case reports along with review of literature by Anu Punnen Kocheril, T Sathish Kumar, Dharshini Sathishkumar

“…In literature, levamisole-induced immune manifestations were described mostly in association with its use in treatment of rheumatoid arthritis, malignancies, and recently, in relation to the use of illicit cocaine contaminated with levamisole among adults. …”
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A Unique Case of Cardiac Arrest following K2 Abuse by Saif Ibrahim, Farah Al-Saffar, Thomas Wannenburg

“…The causative association of sudden death with cocaine, methadone, and volatile agents is well established (Adgey et al. (1995) and Isner et al. (1986)). …”
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Successful Use of Ertapenem for the Treatment of Enterobacter cloacae Complex Infection of the Central Nervous System (CNS) by Sunish Shah, Dayna McManus, Jeffrey E. Topal

“…A 55-year-old female with a past medical history of cocaine use and hypertension was admitted for intracranial hemorrhage requiring right decompressive craniotomy with duraplasty. …”
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Prevalence of dual diagnosis in the south of Peru: descriptive clinical study by Jonathan A. Zegarra-Valdivia, Brenda Nadia Chino Vilca, Ernesto Cazorla Perez

“…Alcohol was the most used substance, followed by cannabis marijuana and cocaine base (PBC). The socio-family and individual vulnerability of the population is evidence for protection or resistance to mental illness, as well as the lack of implementation of effective policies in mental health care for dual disorders, showing worse prognosis and indexes every time higher.…”
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Current Controversies in the Prediction, Diagnosis, and Management of Cerebral Vasospasm: Where Do We Stand? by Young Lee, Scott L. Zuckerman, J. Mocco

“…Evidence regarding the effect of age, smoking, and cocaine use on the incidence and outcome of vasospasm is reviewed. …”
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Exploring the impact of xenobiotic drugs on forensic entomology for accurate post-mortem interval estimation by Sapna Jain, Jonathan J. Parrott, Gulnaz T. Javan

“…This systematic overview delves into the influence of drugs such as Morphine, heroin, Opiates, and cocaine on the variables affecting the use of forensically significant insects as evidence tools. …”
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Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review by Amber N. Edinoff, Natalie W. Wu, Catherine A. Nix, Bryce Bonin, Rama Mouhaffel, Stephen Vining, William Gibson, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye

“…Of particular interest to the subject at hand, ketamine is promising in treating individuals addicted to opioids, alcohol, and cocaine. Therapeutically administered cannabinoids have been proposed for the treatment of multiple illnesses. …”
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