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161
The Effect of Transobturator Tape Surgery on Female Sexual Functions: A Systematic Review
Published 2020-08-01“…Results: A total of 24 clinical trials were evaluated. The most frequently administered scales were the female sexual function index and The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire -12. …”
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162
Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects
Published 2025-02-01“…Nectin-4-targeted approaches, such as ADCs, oncolytic viruses, photothermal therapy and immunotherapy, have shown promising results in early-phase clinical trials. These therapies offer novel strategies for delivering targeted treatments to Nectin-4-expressing cancer cells, enhancing treatment efficacy and minimizing off-target effects. …”
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163
Exploiting question-answer framework with multi-GRU to detect adverse drug reaction on social media
Published 2025-02-01“…The dilemma arises from the inherent impossibility of conducting a comprehensive evaluation of a drug before its market release, constrained by the limitations in scale and duration of clinical trials. Therefore, the post-marketing detection of ADRs in a timely and accurate manner becomes imperative. …”
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164
Anti-Inflammatory and Antimicrobial Effects of Herbal Formulation Called Apo-Taat Using Extended-Spectrum ß-Lactamase-Producing Escherichia coli Isolates
Published 2025-01-01“…Furthermore, safety and clinical trials should be conducted in the future.…”
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165
Neonatal Surgery Intensive Care Unit: Hacettepe University Experience
Published 2023-08-01“…The protocol was registered with Clinical Trials.gov identifier NCT04734002. RESULTS: The total number of newborns admitted to the neonatal intensive care unit was 5442. …”
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166
Phytoconstituent analysis, bioactivity, and safety evaluation of various colors of Chrysanthemum morifolium flower extracts for cosmetic application
Published 2025-02-01“…However, further studies, including human clinical trials, are needed to confirm these biological activities and safety profiles.…”
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167
The effect of azithromycin treatment on respiratory morbidity in children with down syndrome
Published 2025-01-01“…Conclusion The significant reduction in respiratory LOS suggests the potential benefits of Azithromycin in children with DS, and emphasizes the need for larger clinical trials to determine optimal use and long-term effects in this vulnerable population.…”
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168
Mindfulness-based (non-contact) boxing therapy (MBBT) for depression and anxiety: A feasibility study.
Published 2025-01-01“…Further well-designed randomized clinical trials are warranted to confirm the clinical benefits of MBBT.…”
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169
Antisecretory factor in severe traumatic brain injury (AFISTBI): protocol for an exploratory randomized placebo-controlled trial
Published 2025-02-01“…Trial registration ClinicalTrials.gov NCT04117672. Registered on September 17, 2017. …”
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170
Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine
Published 2024-12-01“…After passing the clinical trials, the mentioned product can be effective as a product derived from herbal compounds for pain control.…”
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171
The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (H...
Published 2025-02-01“…GLP-1R agonists, including semaglutide and liraglutide, have demonstrated significant cardioprotective effects, such as improving vascular endothelial function, reducing inflammation, and preventing atherosclerosis. Clinical trials, such as the STEP-HFpEF trial, have shown positive results in reducing symptoms and physical restrictions in HFpEF patients. …”
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172
ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma
Published 2023-03-01“…Currently, there are few clinical trials investigating the use of CAR-T cells in HNSCC/OSCC; however, results from trials investigating similar solid tumours, such as breast cancer, can be adopted to help evaluate the use of CAR-T in this cancer. …”
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173
Microbubble dynamics in brain microvessels.
Published 2025-01-01“…Focused ultrasound stimulation of microbubbles is being tested in clinical trials for its ability to deliver drugs across the blood-brain barrier (BBB). …”
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174
Effects of distant biofield energy healing on adults associated with psychological and mental health-related symptoms: a randomized, placebo-controlled, double-blind study
Published 2024-08-01“…However, due to insufficient scientific studies on biofield therapies, authors planned this clinical trial to examine the safety and effectiveness of biofield therapy in treating symptoms of psychological and mental health and to explore parameters for its effectiveness…”
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175
Metabolomic profile and its association with the diagnosis of prostate cancer: a systematic review
Published 2024-12-01“…Methods We conducted a search strategy in MEDLINE (OVID), EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) from 2008 to the present. We included Clinical trials and analytical and descriptive observational studies that reported metabolite results and metabolite profiles in serum, tissue, urine, and seminal fluid. …”
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176
Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?
Published 2025-02-01“…In this context, a few clinical trials have described a diminished requirement for oxygen therapy during anti-VEGF treatment of SARS-CoV-2 infection. …”
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177
Quality of Life in Wilson’s Disease: A Systematic Literature Review
Published 2021-12-01“…**Methods:** To address this gap in the literature, we conducted a systematic literature review in MEDLINE and EMBASE to identify observational studies and clinical trials reporting QOL outcomes among people living with WD. …”
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178
PRESBYACOUSSIS: JUSTIFICATION OF DIAGNOSIS IN SCREENING CONDITIONS
Published 2024-12-01“…After selection and analysis, the results of 6 studies were taken into work, including 3 randomized clinical trials and 3 observational studies. Taking into account global trends, an analysis of the validity of the search for effective methods for diagnosing presbycusis was carried out. …”
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179
Pancreatic Perivascular Epithelial Cell Tumor (PEComa) with Liver Metastasis: a Case Report and Literature Review
Published 2023-08-01“…To determine clearer criteria for the diagnosis and differential diagnosis of PEComa, to identify criteria for the malignancy of these tumors, to develop treatment tactics and further dynamic monitoring, a set of statistical data of significant group and randomized clinical trials are needed. Pancreatic PEComas in this group are extremely rare and often have a benign course. …”
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180
Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting progr...
Published 2025-02-01“…Trial registration This trial is registered on ClinicalTrials.gov : NCT06701877.…”
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