Association of immunoglobulin G N-glycosylation with carotid atherosclerotic plaque phenotypes and actual clinical cardiovascular events: a study protocol for a longitudinal prospe... by Gehendra Mahara, Hongxia Zhang, Cuihong Tian, Xuerui Tan

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Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective by Wenhao Liao, Jing Wang, Yuchen Li

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Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53 by Yidan Wang, Todd G. Kroll, Linhui Hao, Zhi Wen

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Improvement in Impaired Social Cognition but Not Seizures by Everolimus in a Child with Tuberous Sclerosis-Associated Autism through Increased Serum Antioxidant Proteins and Oxidan... by Kunio Yui, George Imataka, Hitomi Sasaki, Yohei Kawasaki, Tohru Okanshi, Ryoichi Shiroki, Shigemi Yoshihara

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Association of dietary acid load with inflammatory markers, oxidative stress, and clinical features in patients with knee osteoarthritis by Jalal Moludi, Akram Rahimi, Shaimaa A. Qaisar, Soudabeh Hamedi-Shahraki, Farshad Amirkhizi

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Transcriptional Profiling Reveals Kidney Neutrophil Heterogeneity in Both Healthy People and ccRCC Patients by Yiliang Meng, Kai Cai, Jingjie Zhao, Keyu Huang, Xiumei Ma, Jian Song, Yunguang Liu

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Arsenic and fifteen other metal (loid)s exposure of children living around old mines in the south of France by Igor Pujalté, Zeno Loi, Alice Bernard, Lionel Moulis, Sophie Delpoux, Jacques Gardon

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Successful Treatment of Caesarean Scar Pregnancies by Local Treatment Only by Shinji Tanigaki, Chie Nagata, Kazunori Ueno, Nobuaki Ozawa, Shinichi Nagaoka, Kei Tanaka, Haruhiko Sago, Mitsutoshi Iwashita

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Process Assessment of Fencer's Parents within the scope of the Covid-19 Normalization Steps by Yusuf Barsbuğa

“…For this study, an approval was received from the Ethics Committee for Non-Invasive Clinical Research of the School of Sport Sciences of Seljuk University. …”
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Mechanism of hyperbaric oxygen therapy downregulating H-type angiogenesis in subchondral bone of knee osteoarthritis through the PHD2/HIF-1α pathway by Jianjian Wang, Wen Yu, Yuxin Zhang, Bo Chen, Zhaoxiang Meng

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The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus by Rujie Zheng, Wenjuan Song, Jie Lu, Mingyue Yuan, Xiaotong Sun, Chengzhi Lu

“…Abstract Background Sodium-glucose transport protein 2 inhibitors (SGLT2i) have been widely used to treat patients with type 2 diabetes mellitus (T2DM) and have demonstrated protective effects against certain cardiovascular diseases. However, no clinical research has been conducted to explore the relationship between SGLT2i and the risk of aortic aneurysm (AA). …”
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Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications by Nick Boyne, Alison Duke, Jack Rea, Adam Khan, Alec Young, Jared Van Vleet, Matt Vassar

“…Journals and regulatory bodies should enforce compliance and future efforts should develop mechanisms to monitor and correct reporting inconsistencies, enhancing the trustworthiness of safety data in clinical research.…”
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Protocol for a prospective quasi-experimental study on SARS-CoV-2 transmission during outdoor sports events in France: the COVID-ESO project by Frédéric Laurent, Philippe Vanhems, Christelle Elias, Pascal Roy, Sandrine Nail-Billaud, Patrick Basset, Emmanuelle Dantony, Mathieu Fauvernier

“…Ethical approval has been obtained for the Clinical research and committee of South West of France, 10 June 2021. …”
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Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation by Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun

“…Despite these advantages, ciprofol’s clinical research is still emerging. This study compares the median effective dose (ED50) and adverse reactions of ciprofol and propofol, in conjunction with sufentanil, for suppressing cardiovascular responses during tracheal intubation. …”
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Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion by Michelle Pfaffenlehner, Max Behrens, Daniela Zöller, Kathrin Ungethüm, Kai Günther, Viktoria Rücker, Jens-Peter Reese, Peter Heuschmann, Miriam Kesselmeier, Flavia Remo, André Scherag, Harald Binder, Nadine Binder, for the EVA4MII project

“…Abstract Background The integration of real-world evidence (RWE) from real-world data (RWD) in clinical research is crucial for bridging the gap between clinical trial results and real-world outcomes. …”
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The use of the long peroneal muscle tendon as an autograft during the primary plastics of the anterior cruciate ligament: a systematic review by Aleksey P. Prizov, Anatoly M. Vostrikov, Dmitry V. Skvortsov, Fedor L. Lazko, Maxim F. Lazko, Evgeniy A. Belyak, Alexandra V. Krytaeva

“…These parameters were used for evaluating the clinical research works on using the autograft made from the long peroneal muscle tendon for the reconstruction of the anterior cruciate ligament. …”
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An assessment of burden associated with problem joints in children and adults with moderate or severe haemophilia A: analysis of the CHESS-Paediatrics and CHESS II cross-sectional... by Paul McLaughlin, Hortensia De la Corte-Rodriguez, Tom Burke, Francis Nissen, Martynas Aizenas, Katya Moreno, Jamie O’Hara

“…Abstract Background Clinical research has offered many definitions and fragmented perspectives of joint morbidity in haemophilia. …”
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Neoadjuvant apatinib addition to sintilimab and carboplatin-taxane based chemotherapy in patients with early triple-negative breast cancer: the phase 2 NeoSAC trial by Guoshuang Shen, Zhilin Liu, Miaozhou Wang, Yi Zhao, Xinlan Liu, Yujin Hou, Wenbiao Ma, Jingqi Han, Xiaofeng Zhou, Dengfeng Ren, Fuxing Zhao, Zitao Li, Shifen Huang, Yongzhi Chen, Yingjian He, Yan Liu, Zijun Zhu, Yongxin Li, Jinming Li, Mengting Da, Hongnan Mo, Feng Du, Liang Cui, Jing Bai, Zhen Liu, Fei Ma, Jiuda Zhao

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Causal Associations Between Sarcopenia and Gestational Diabetes Mellitus by Huang Y, Zhao S, Hong J, Shen L, Wang Z, Wang D

“…Yihong Huang,1,2,* Shanshan Zhao,1,2,* Jiajun Hong,1,2 Lixia Shen,1,2 Zilian Wang,1,2 Dongyu Wang1,2 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Clinical Research Center for Obstetrical and Gynecological Diseases, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongyu Wang; Zilian Wang, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, No. 58 Zhongshan Er Road, Guangzhou, People’s Republic of China, Email wangdy28@mail.sysu.edu.cn; wangzil@mail.sysu.edu.cnIntroduction: Sarcopenia may affect the onset of gestational diabetes mellitus (GDM). …”
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Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments by Liu C, Liu W, Lu H, Fan Y, Wang A

“…Chunliu Liu,1– 3,* Wei Liu,1,2,* Hang Lu,1,2 Yihua Fan,4 Aihua Wang1,2 1Department of Rheumatism and Immunity, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China; 3Department of Respiratory Medicine, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, People’s Republic of China; 4Department of Rheumatism and Immunity, Hospital of Chengdu University of Traditional Chinese Medicine, Sichuan Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Liu, Email fengshiliuwei@163.comPurpose: Baicalin is a flavonoid of Scutellaria baicalensis Georgi. …”
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