Authors' reply: Re: Koga et al. Retrieval‐augmented generation versus document‐grounded generation: a key distinction in large language models by Katherine J Hewitt, Isabella C Wiest, Jakob N Kather

“…The Journal of Pathology: Clinical Research…”
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Platinum drugs upregulate CXCR4 and PD‐L1 expression via ROS‐dependent pathways, with implications for novel combined treatment in gastric cancer by Xiaoyu Kang, Lin Zhang, Shushang Liu, Fei Wang, Haiming Liu, Fenli Zhou, Fei Wu, Haohao Zhang, Daiming Fan, Yongzhan Nie, Zhangqian Chen

“…The Journal of Pathology: Clinical Research…”
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Predictive abilities of acculturation for differences in self-rated health among international medical students from Medical University – Sofia by Joana Simeonova, Angelika Velkova, Lidia Georgieva, Peshka Pesheva, Kristina Popova, Nikolai Hristov, Elia Georgieva, Maria Pravchanska

“…Journal of Biomedical & Clinical Research…”
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Immunohistochemistry‐based molecular subtypes of urothelial carcinoma derive different survival benefit from platinum chemotherapy by Csilla Olah, Oleksandr Shmorhun, Gilbert Georg Klamminger, Josefine Rawitzer, Lara Sichward, Boris Hadaschik, Mulham Al‐Nader, Ulrich Krafft, Christian Niedworok, Melinda Váradi, Peter Nyirady, Andras Kiss, Eszter Szekely, Henning Reis, Tibor Szarvas

“…The Journal of Pathology: Clinical Research…”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

“…Breast Cancer: Basic and Clinical Research…”
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CT Texture Analysis in Breast Cancer Patients Undergoing CT-Guided Bone Biopsy: Correlations With Histopathology by Silvio Wermelskirchen, Jakob Leonhardi, Anne-Kathrin Höhn, Georg Osterhoff, Nikolas Schopow, Susanne Briest, Timm Denecke, Hans-Jonas Meyer

“…Breast Cancer: Basic and Clinical Research…”
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Where Are We Heading with Noninvasive Clinical Vascular Physiology? Why and How Should We Assess Endothelial Function? by Elizabeth A. Ellins, Julian P. J. Halcox

“…There are several invasive and noninvasive methods available to the clinical researcher for the assessment of endothelial function. …”
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The effect of caregiver opinion leaders to increase demand for evidence-based practices for youth anxiety: A cluster randomized controlled trial by Margaret E. Crane, Marc S. Atkins, Sara J. Becker, Jonathan Purtle, Gillian C. Dysart, Sydney Keller, Olivia Brauer, Sirina E. Tiwari, Thomas M. Olino, Lara Baez, John Lestino, Philip C. Kendall

“…Schools within 1.5-hr drive of Philadelphia, PA were cluster-randomized ( k  = 25; two-arm prospective randomization) to the OL condition (presented by a clinical researcher and local caregiver OL; n  = 119 participants) or the researcher-only condition ( n  = 143 participants). …”
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METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients by Xin Chen, Yuan Qin, Xian Wang, Hao Lei, Xiaochen Zhang, Houzhuo Luo, Changgang Guo, Weifu Sun, Shishu Fang, Wen Qin, Zuolin Jin

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Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer by Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Wei Zhang, Shuping Wu, Linfei Hu, Xianhui Ruan, Xiangqian Zheng, Ming Gao, Jingzhu Zhao

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REVIEW by Alexandru Grigorescu

“…Ethics in clinical research …”
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Gli1+ Cells Residing in Bone Sutures Respond to Mechanical Force via IP3R to Mediate Osteogenesis by Xiaoyao Huang, Zihan Li, Peisheng Liu, Meiling Wu, An-qi Liu, Chenghu Hu, Xuemei Liu, Hao Guo, Xiaoxue Yang, Xiaohe Guo, Bei Li, Xiaoning He, Kun Xuan, Yan Jin

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The implementation of whole-genome sequencing for Mycobacterium tuberculosis in Vietnam by D.T. Huong, T.M. Walker, D.T. Ha, K.T.T. Ngoc, V.N. Trung, L.T. Nam, P.T.T. Ngoc, L.T. Nguyet, N.T. Thanh, N.H. Minh, N.K. Cuong, N.V. Khiem, H.V.T. Ngoc, T.T.T. Bich, H.N. Hong, P.P. Trieu, L.K. Lan, K. Lan, N.N. Hue, N.T.L. Huong, T.L.T.N. Thao, N.L. Quang, T.D.D. Anh, D.W. Crook, G.E. Thwaites, N.T.T. Thuong, N.B. Hoa, D.V. Luong, N.V. Hung

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Combined pyrotinib and fulvestrant for hormone receptor‐positive and HER2‐positive metastatic breast cancer: A multicenter, single‐arm, phase II trial by Jianli Zhao, Yunfang Yu, Wei Ren, Linxiaoxiao Ding, Yongjian Chen, Peng Yuan, Jian Yue, Yaping Yang, Guorong Zou, Tao Chen, Jie Chai, Li Zhang, Wenjing Wu, Yinduo Zeng, Xiujuan Gui, Yangyang Cai, Simin Luo, Zhongyu Yuan, Kang Zhang, Herui Yao, Ying Wang

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Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3+ CD8+ T Cells and Survival in Diffuse Large B Cell Lymphoma by Tingting Zhang, Tianyuan Ren, Zheng Song, Jing Zhao, Lei Jiao, Zhenzhen Zhang, Jin He, Xianming Liu, Lihua Qiu, Lanfang Li, Shiyong Zhou, Bin Meng, Qiongli Zhai, Xiubao Ren, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

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Adverse events in the nervous system associated with blinatumomab: a real-world study by Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

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Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway by Guanjun Li, Huiying Li, Peili Wang, Xinzhou Zhang, Wenhua Kuang, Ling Huang, Ying Zhang, Wei Xiao, Qingfeng Du, Huan Tang, Jigang Wang

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Using maternal sepsis patient journeys to map and prioritise barriers to quality maternal healthcare in Malawi: a multidisciplinary stakeholder consultation workshop by Yamikani Chimwaza, Dalisto Ndaferankhande, Leonard Mndala, Chifundo Ndamala, Emily Lifa, Mercy Machilika, Esther Mwagomba, Bernard Dossie, Meliya Kwelepeta, Bertha Maseko, David Lissauer, Maria Lisa Odland

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Eupalinolide B inhibits periodontitis development by targeting ubiquitin conjugating enzyme UBE2D3 by Wenhua Kuang, Ruishen Zhuge, Ping Song, Letai Yi, Shujie Zhang, Ying Zhang, Yin Kwan Wong, Ruixing Chen, Junzhe Zhang, Yuanbo Wang, Dandan Liu, Zipeng Gong, Peili Wang, Xiangying Ouyang, Jigang Wang

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The landscape of cell regulatory and communication networks in the human dental follicle by Jia-Ning Liu, Jia-Ning Liu, Jiong-Yi Tian, Lu Liu, Lu Liu, Yuan Cao, Yuan Cao, Xiao Lei, Xiao Lei, Xiao-Hui Zhang, Xiao-Hui Zhang, Zi-Qi Zhang, Zi-Qi Zhang, Jun-Xi He, Jun-Xi He, Chen-Xi Zheng, Chao Ma, Sheng-Feng Bai, Bing-Dong Sui, Fang Jin, Ji Chen, Ji Chen

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