How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data by Tom Marshall, Elizabeth Sapey, Miles D Witham, Steve Harris, Rachel Cooper, Chris Plummer, Felicity Evison, James Wason, Heather J Cordell, Suzy Gallier, Fiona E Matthews, Ewan Pearson, Avan A Sayer, Mervyn Singer, Joanne Field, Mohammed Osman, Sian Robinson, Victoria Bartle, Thomas Scharf, Jadene Lewis, Rominique Doal, Peta le Roux, Ray Holding, Paolo Missier

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Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort stud... by Jian Chen, Jian Chen, Haixin Huang, Ruichen Zhang, Yueqiang Fu, Chunmei Jing

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New Insights on Properties and Spatial Distributions of Skeletal Stem Cells by Jun-qi Liu, Qi-wen Li, Zhen Tan

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Controversies and future directions of endoscope in breast surgery by CAO Xuchen

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Loud Snoring is A Risk Factor for Occupational Injury in Farmers by James A Dosman, Louise Hagel, Robert Skomro, Xiaoqun Sun, Andrew G Day, William Pickett

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Umbilical Cord Tissue-Derived Cells as Therapeutic Agents by Olga Maslova, Miroslav Novak, Peter Kruzliak

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Mediation Effect of Resilience Between Social Support and Depression Symptoms in Patients With Strabismus: A Cross-Sectional Study by Mo Y, Zhang H, Yu X, Xu Z, Xiao H, Gao L, Wang Y

“…Yawen Mo,1 Huiting Zhang,1 Xinping Yu,1 Zhihong Xu,1 Huiming Xiao,2 Lingling Gao,3 Yinghuan Wang1 1Department of Strabismus and Amblyopia, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China; 2Department of Nursing Administration, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China; 3School of Nursing, Sun Yat-Sen University, Guangzhou, People’s Republic of ChinaCorrespondence: Lingling Gao; Yinghuan Wang, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, No. 54, Xianlie South Road, Yuexiu District, Guangzhou, People’s Republic of China, Email gaoll@mail.sysu.edu.cn; wangyinghuan@gzzoc.comPurpose: The prevalence of depression symptoms in patients with strabismus is high. …”
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Selection of the appropriate design in biomedical research: foundations and considerations for evidence-based practice. Part I by Raúl Aguilera Eguía, Ángel Roco Videla, Olga Patricia López Soto, Brenda Herrera Serna, Georgiy Polevoy Polevoy, Héctor Fuentes Barria

“…In clinical research, it is crucial to make an appropriate selection of the research design. …”
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Utilization of Mean Platelet Volume for Predicting Ischemic Heart Disease in Diabetic and Non-Diabetic Patients by Maryam Arefnia, Toktam Hosseinnezhad Ariani, Mohammadali Ghodsirad, Toktam Alirezaei, Elinaz Hosseinzadeh, Mahesti Amoui, Elaheh Pirayesh, Ghazaal Norouzi

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Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 by Liping Liu, Anding Xu, Xin Wang, Yongjun Wang, Yilong Wang, Zhongrong Miao, Yuming Xu, Benyan Luo, Bin Peng, Yong Huo, Qiang Dong, Zixiao Li, Xingquan Zhao, Caiyun Wang, Hongqiu Gu, Chunjuan Wang, Zhengqi Lu, Yunyun Xiong, Shuo Wang, Lihua Wang, Linong Ji, Xiaoping Gao, Wenzhi Wang, Yi Yang, Kai Wang, Junbo Ge, Xunming Ji, Jun Pu, Tong Zhang, Bo Hu, Ning Wang, Yun Xu, Jinsheng Zeng, Gang Zhao, Zhong Chen, Aoming Jin, Xiaoyuan Niu, Jiong Shi, Shuya Li, Jianmin Zhang, Ling Yin, Dou Li, Dehong Lu, Chao Qin, Dapeng Sun, Kaifu Ke, Yanhui Du, Xiaoning Zhang, Fudong Shi, Jianxin Zhou, Lan Chu, Li Guo Li He, Shengnian Zhou, Weixin Cai, Xiaomu Wu, Zhiyi He

“…It is anticipated that future clinical research will further advance areas such as innovative thrombolytic agents, expanded indications for thrombolysis and mechanical thrombectomy.…”
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Human adenovirus species B knob proteins as immunogens for inducing cross-neutralizing antibody responses by Zhenwei Liu, Yuting Xian, Jixian Lan, Zhichao Zhou, Xiao Li, Rong Zhou, Dehui Chen, Xingui Tian

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Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011–2018 by Yaping Deng, Yingting Luo, Yilei Shen, Yong Zhao, Wei Cao, Jie Cao, Lijuan Xu, Lin Kong

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Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway by Sisi Wei, Xinyi Fan, Xiaoya Li, Wei Zhou, Zhihua Zhang, Suli Dai, Huilai Lv, Yueping Liu, Baoen Shan, Lianmei Zhao, Qimin Zhan, Yongmei Song

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Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

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Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States by Qu Zhang, Yemei Wu, Bo Luo

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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

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Involving national stakeholders in a systems approach to map drivers of childhood obesity and actions to prevent childhood obesity in Denmark: the Generation Healthy Kids Study by Knud Ryom, Paul Bloch, Ulla Toft, Didde Høeg, Louise T. Thomsen, Steven Allender, Harry Rutter, Adrian Bauman, Rikke Fredenslund Krølner, Anders Blædel Gottlieb Hansen

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Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children by Olesya Fedoryak, Charles Arama, Issa Diarra, Bouréma Kouriba, Michel Chrétien, Majambu Mbikay

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Reproducibility of Glucose Fluctuations Induced by Moderate Intensity Cycling Exercise in Persons with Type 1 Diabetes by Gabriel Tafdrup Notkin, Peter Lommer Kristensen, Ulrik Pedersen-Bjergaard, Andreas Kryger Jensen, Stig Molsted

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Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B by R. A. Cardoso, A. A. Melo Filho, M. C. C. Melo, D. M. Lyerly, T. D. Wilkins, A. A. M. Lima, R. A. Ribeiro, G. E. P. Souza

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