Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy by Laura Grunewald, Lena Andersch, Konstantin Helmsauer, Silke Schwiebert, Anika Klaus, Anton G. Henssen, Teresa Straka, Marco Lodrini, Sebastian G. Wicha, Steffen Fuchs, Falk Hertwig, Frank Westermann, Alice Vitali, Carlotta Caramel, Gabriele Büchel, Martin Eilers, Kathy Astrahantseff, Angelika Eggert, Uta E. Höpken, Johannes H. Schulte, Thomas Blankenstein, Kathleen Anders, Annette Künkele

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Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS... by Ramakanth Kavuluru, Xuan Wang, Paul Avillach, Florence Bourgeois, Kee Yuan Ngiam, Gabriel A Brat, Isaac Kohane, Tianxi Cai, Yuk-Lam Ho, Yuan Luo, Harrison G Zhang, Kelly Cho, Vincent Benoit, Antoine Neuraz, Chuan Hong, Sehi L'Yi, Griffin Weber, Bryce W Q Tan, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Nathan P Palmer, Alberto Malovini, Valentina Tibollo, Meghan R Hutch, Molei Liu, Riccardo Bellazzi, Luca Chiovato, Fernando J Sanz Vidorreta, Trang T Le, William Yuan, Bertrand Moal, Michele Morris, David A Hanauer, Sarah Maidlow, Kavishwar Wagholikar, Shawn Murphy, Hossein Estiri, Adeline Makoudjou, Patric Tippmann, Jeffery Klann, Robert W Follett, Nils Gehlenborg, Gilbert S Omenn, Zongqi Xia, Arianna Dagliati, Shyam Visweswaran, Lav P Patel, Danielle L Mowery, Emily R Schriver, Malarkodi Jebathilagam Samayamuthu, Sara Lozano-Zahonero, Daniela Zöller, Amelia L M Tan, Byorn W L Tan, John H Holmes, Petra Schubert, Brett K. Beaulieu-Jones, Miguel Pedrera-Jiménez, Noelia García-Barrio, Pablo Serrano-Balazote, Andrew South

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Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLU... by Brian Hiestand, Phillip Levy, W Frank Peacock, Brigitte M Baumann, Richard M Nowak, Amy Hsu, Joseph Varon, Chad M Cannon, David M Cline, Pierre Borczuk, Abhinav Chandra, Deborah B Diercks, Preeti Jois, Brian Kaminski, Jon W Schrock

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Investigating the effects of knee valgus orthosis on knee joint contact forces among subjects with knee osteoarthritis: A case series study by Mohammad Taghi KARIMI, Mahmood BAHRAMIZADEH, Hanieh KHALILIYAN, Majid ANSARI, Kavita BATRA, Aanuoluwapo AFOLABI, Olayinka ILESANMI, Lukasz SZARPAK, Hicham KHABBACHE, Gabriella NUCERA, Aldo SITIBONDO, Farhad GHAFFARI, Arash SHARAFATVAZIRI, Francesco CHIRICO

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Fully automatic reconstruction of prostate high-dose-rate brachytherapy interstitial needles using two-phase deep learning-based segmentation and object tracking algorithms by Mohammad Mahdi Moradi, Zahra Siavashpour, Soheib Takhtardeshir, Eman Showkatian, Ramin Jaberi, Reza Ghaderi, Bahram Mofid, Farzad Taghizadeh-Hesary

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The impact of the live broadcast of Stromae’s song L’enfer on social media publications, calls to the national helpline, and suicide attempt rates in France by Charles-Edouard Notredame, Chloé Saint-Dizier, Antoine Lamer, Erika Nogue, Emile Fares, Mohamed Lemdani, Guillauma Vaiva, Philippe Courtet, Emilie Olié

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Study protocol on risk factors for the diagnosis of gestational diabetes mellitus in different trimesters and their relation to maternal and neonatal outcomes (GDM-RIDMAN) by Khalida Ismail, Boon How Chew, Iliatha Papachristou Nadal, Angus Forbes, Nurul Iftida Basri, Rozita Zakaria, Pamela Phui Har Yap, Veronika Rysinova, Intan Nureslyna Samsudin, Nurain Mohd Noor, Ziti Akthar Supian, Haslinda Hassan, Fuziah Paimin, Siti Rohani Mohamed Alias, Norizzati Bukhary Ismail Bukhary, Madeleine Benton

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Simultaneous Liver Venous Deprivation Following Hepatic Arterial Chemoembolization Before Major Hepatectomy for Hepatocellular Carcinoma: A New Methods to Achieve Hypertrophy Liver... by Zhang S, Song R, Hou C, Yao H, Xu J, Zhou H, Li S, Cai W, Fei Y, Meng F, Yin D, Wang J, Zhang S, Liu Y, Wang J, Liu L

“…Shenyu Zhang,1,* Ruipeng Song,1,* Changlong Hou,2,* Huanzhang Yao,1 Jun Xu,2 Hangcheng Zhou,3 Shaopeng Li,4 Wei Cai,1 Yipeng Fei,2 Fanzheng Meng,1 Dalong Yin,1 Jiabei Wang,1 Shugeng Zhang,1 Yao Liu,1 Jizhou Wang,1,5,6 Lianxin Liu1,5,6 1Department of Hepatobiliary Surgery, Centre for Leading Medicine and Advanced Technologies of IHM, the first affiliated hospital of ustc, Division of Life Sciences and Medicine, university of science and technology of china, Hefei, Anhui, 230001, People’s Republic of China; 2Department of Intervention, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 3Department of Pathology, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 4Department of Imaging, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 5Anhui Provincial Key Laboratory of Hepatopancreatobiliary Surgery, Hefei, Anhui, 230001, People’s Republic of China; 6Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei, Anhui, 230001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lianxin Liu; Jizhou Wang, Email liulx@ustc.edu.cn; wangjoe@ustc.edu.cnPurpose: Liver venous deprivation (LVD; simultaneous portal vein embolization and hepatic vein embolization) has been the latest surgical strategy for rapid future liver remnant (FLR) hypertrophy. …”
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Blood proteomics and multimodal risk profiling of human volunteers after incision injury: A translational study for advancing personalized pain management after surgery by Daniel Segelcke, Julia R. Sondermann, Christin Kappert, Bruno Pradier, Dennis Görlich, Manfred Fobker, Jan Vollert, Peter K. Zahn, Manuela Schmidt, Esther M. Pogatzki-Zahn

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Noninvasive imaging biomarker reveals invisible microscopic variation in acute ischaemic stroke (≤ 24 h): a multicentre retrospective study by Kui Sun, Rongchao Shi, Xinxin Yu, Ying Wang, Wei Zhang, Xiaoxia Yang, Mei Zhang, Jian Wang, Shu Jiang, Haiou Li, Bing Kang, Tong Li, Shuying Zhao, Yu Ai, Jianfeng Qiu, Haiyan Wang, Ximing Wang

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Global and China trends and forecasts of disease burden for female lung Cancer from 1990 to 2021: a study based on the global burden of disease 2021 database by Bilu Li, Yuyan Wu, Yanhong Zhang, Chengyun Hu, Xue Li, Shanshan Luo, Chenyu Sun, Iyad Yousef, Yefei Wang, Chaoliang Tang

“…The aim is to provide a reliable theoretical basis and reference value for clinical research and practice in female lung cancer and offer guidance for resource allocation and policy-making in society. …”
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Differential Diagnosis, Clinical Characteristics, and Interventions of Braid-Like Coronary Artery: Case Series Analysis Based on Optical Coherence Tomography by Wen-Xiu Leng, Huan-Huan Wang, Hai Ming Liu, Ying Song, Lian-Jun Xu, Jing-Jing Xu, Xue-Yan Zhao, Xiao-Yan Tan, Rong Li, Zhan Gao, Li-Jian Gao, Jue Chen, Jin-Qing Yuan, Yue-Jin Yang, Ji-Lin Chen

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CD8+T cells and monocytes were associated with brain alterations in human immunodeficiency virus-infected individuals with cognitive impairment by Xin Zhang, Zhen Li, Jiahao Ji, Yundong Ma, Guangqiang Sun, Xue Chen, Ling Zhang, Tong Zhang, Yulin Zhang, Yang Zhang

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Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages by Fred Owino, Fred Owino, Fred Owino, Caroline Kijogi, Caroline Kijogi, Caroline Kijogi, Omu Anzala, Omu Anzala, Edwin Walong, Obiero Jael, Steven G. Nyanjom, Agola Lelo Eric, Bernard N. Kanoi, Bernard N. Kanoi, Jesse Gitaka, Jesse Gitaka

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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

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Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial by Jaeyeon Kim, Yiseul Choi, Yoolbin Song, Wonse Park

“…Trial RegistrationClinical Research Information Service (CRIS), Republic of Korea, KCT0009094; https://cris.nih.go.kr/cris/search/detailSearch.do?…”
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Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP by Yi Wang, Weiwei Qiu, Stace Kernodle, Carly Parker, Marc-Antonio Padilla, Jiaao Su, Abigail J. Tomlinson, Stephanie Oldham, Joss Field, Elise Bernard, David Hornigold, Christopher J. Rhodes, David P. Olson, Randy J. Seeley, Martin G. Myers, Jr

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Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies by Cui Y, Liu X, Feng S

“…Yuqing Cui,1,2 Xin Liu,1,2 Sizhou Feng1,2 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, People’s Republic of China; 2Tianjin Institutes of Health Science, Tianjin, 300020, People’s Republic of ChinaCorrespondence: Sizhou Feng, Email doctor_szhfeng@163.comPurpose: Since the publication of the 2011 Infectious Diseases Society of America (IDSA) guidelines for empirical treatment of febrile neutropenia (FN), there have been significant shifts in pathogen profiles and emerging challenges in treatment. …”
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Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults by Clément Lanfranchi, Nadège Zanou, Jérôme Feige, Umberto DeMarchi, Aurélie Hermant, Ornella Cominetti, Eugenia Migliavacca, Alba Moreno-Asso, Astrid Hostrman, Sara Mistro, Nicolas Place

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Cerium-based nanoplatform for severe acute pancreatitis: Achieving enhanced anti-inflammatory effects through calcium homeostasis restoration and oxidative stress mitigation by Tingyi Luo, Yujing Tang, Wangcheng Xie, Zhilong Ma, Jian Gong, Yonggui Zhang, Tingsong Yang, Xuyang Jia, Jia Zhou, Zhengyu Hu, Lin Han, Qigang Wang, Zhenshun Song

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