The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock by Gennaro De Pascale, Salvatore Lucio Cutuli, Mariano Alberto Pennisi, Massimo Antonelli

“…Strategies of replacement therapies in critically ill patients with severe infections are under investigation but still far to be applied in clinical practice.…”
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Local negative pressure technique in abdominal surgery: advantages, disadvantages, controversial issues by A. A. Sazonov, P. N. Romashchenko, I. A. Makarov, R. K. Aliev, N. A. Maistrenko

“…However, the indications for the use of local negative pressure in abdominal surgery have not yet been clarified, which undoubtedly hinders the wider introduction of this promising technique into clinical practice.…”
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Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets? by Athina Kladi-Skandali, Kleita Michaelidou, Andreas Scorilas, Konstantinos Mavridis

“…The most prominent example of lncRNAs application in routine clinical practice is PCA3, a FDA-approved biomarker for prostate cancer. …”
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Health-related quality of life in hemato-oncology patients: role of informativeness and doctor-patient communication by Stella Sremić, Lovorka Brajković, Vanja Kopilaš

“…The results indicate the importance of information that can be implemented in everyday clinical practice, and pave the way for further research on doctor-patient communication.…”
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Quality of registration and adherence to guidelines for blood management in CABG surgeries: a case study by Giulia M.R., Eline Vlot, Thomas van Dijk

“…Decision support systems can be active, data-based, patient-specific and act timely, and can be more useful that adding new clinical practice guidelines. This case study quantifies the quality of the data registration and provides the results for adherence to perioperative PBM guidelines for coronary artery bypass grafting (CABG) procedures during a three-year period (2018 to 2020), in the St. …”
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ChatGPT in Pharmacy Practice: Disruptive or Destructive Innovation? A Scoping Review by Tácio de Mendonça Lima, Michelle Bonafé, André Rolim Baby, Marília Berlofa Visacri

“…ChatGPT has emerged as a promising tool for enhancing clinical practice. However, its implementation raises critical questions about its impact on this field. …”
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Comparison between AI and human expert performance in acute pain assessment in sheep by Marcelo Feighelstein, Stelio P. Luna, Nuno O. Silva, Pedro E. Trindade, Ilan Shimshoni, Dirk van der Linden, Anna Zamansky

“…The fact that the machine can outperform human experts in recognizing pain in sheep when exposed to the same visual information has significant implications for clinical practice, which warrant further scientific discussion.…”
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Anti-Inflammatory Effects of Helminth-Derived Products: Potential Applications and Challenges in Diabetes Mellitus Management by Zhu Y, Chen X, Zheng H, Ma Q, Chen K, Li H

“…Additionally, it discusses the possible applications of these derivatives in DM management and the challenges involved in translating these findings into clinical practice.Keywords: diabetes mellitus, helminth-derived products, anti-inflammatory, immune modulation…”
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Characteristics, Needs, and Perspectives of Individuals Living Alone With Dementia: An Integrative Review by Sara J. Crance, Fang Yu

“…The aim of this integrative review was to understand the characteristics, needs, and perspectives of individuals living alone with dementia as well as the available community resources to guide future research and clinical practice. Methods Electronic (PubMed, CINAHL, and PsycINFO) and manual searches were utilized to identify articles using MeSH terms. …”
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Inflammatory Bowel Disease: Progress Towards a Gene by David A van Heel, Jack Satsangi, Alisoun H Carey, Derek P Jewell

“…Advances in IBD genetics hold the potential to provide knowledge about the disease pathogenesis at the molecular level, with ensuing benefits for clinical practice.…”
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Nanocarriers in skin cancer treatment: Emerging drug delivery approaches and innovations by Laxmi A. Jadhav, Satish K. Mandlik

“…Integrating nanotechnology into clinical practice could elevate the standard of care, offering new hope in managing skin cancer.…”
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Effect of Metadoxine on Chronic Primary Hepatopathies in Canines:  Number of Cases by Paula María Bermúdez-Duarte, José Alfredo Rivera-Rojas

“…Despite significant limitations, this number of cases provides preliminary observation suggesting that metadoxine may improve the clinical condition of dogs with liver disease without altering paraclinical, ultrasound, or histological variables; additional research with a Randomized Clinical Trial design is needed to propose metadoxine indication protocols for canines with hepatopathies in clinical practice. …”
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Misleading Imaging Findings: Bilateral Mylohyoid Defect Presenting as a Submandibular Mass Due to Sublingual Gland Protrusion by Dagnija Grabovska, Junsiyuan Li, Maija Radziņa, Arturs Balodis

“…The etiology of this condition may be congenital or acquired, and although such anatomical variations are common, they often go unrecognized in clinical practice. Sialoceles are cyst-like structures that result from chronic inflammation or ductal injury, indicating underlying problems with drainage efficiency. …”
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Advancements in managing chemotherapy-induced nausea and vomiting: From efficacy to cost-effectiveness by Yuvashree Chandrasekaran, Mukesh Kumar Dharmalingam Jothinathan

“…Meanwhile, our real-life clinical practice is not at its optimal adherence to prevention guidelines. …”
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CLARE-XR: explainable regression-based classification of chest radiographs with label embeddings by Joana Rocha, Sofia Cardoso Pereira, Pedro Sousa, Aurélio Campilho, Ana Maria Mendonça

“…Furthermore, as the regressor is trained on a known set of images, the distance from the coordinates of an inference image to the coordinates of the training set images also allows retrieving similar instances, mimicking the common clinical practice of comparing scans to confirm diagnoses. …”
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Pediatric diabetic ketoacidosis in a patient with Down syndrome. Case report by Jhon Camacho, Daniela Guerrero, Alan Figueroa, Leidy Gómez, Pablo Vásquez-Hoyos

“…This case calls on to contemplate autoimmune complications in patients with DS during clinical practice. Although they are not part of the most frequent reasons for consultation, they cannot be underestimated and should be suspected and treated in a timely manner. …”
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Helicobacter pylori: From Bench to Bedside by N Chiba, A Matisko, P Sinclair, ABR Thomson

“…For persons with known peptic ulcer disease there should be unequivocal acceptance that the good clinical practice of eradicating H pylori will result in substantial savings in health care expenses. …”
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Qualitative study on nurse preceptors’ preparedness, roles and familiarity with the basic principles of teaching and learning in a district hospital in Ghana by Dorothy Serwaa Boakye, Vida Maame Kissiwaa Amoah, Edward Appiah Boateng, John Antwi, Joyce Yeboah, Jennifer Owusu

“…Objective This qualitative study explored the experiences, preparedness, instructional practices and roles of preceptors supervising nursing students in a clinical setting.Design Exploratory descriptive study employing semi-structured interviews.Setting A district hospital in the Kumasi Metropolis accredited for training nursing students in clinical practice.Participants 12 nurse preceptors, each holding at least a Bachelor of Science in Nursing.Major findings Findings revealed gaps in the preparation of preceptors and a lack of a clear definition of preceptors’ roles and responsibilities from the outset, contributing to feelings of under-preparedness. …”
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Micro-CT Microcalcification Analysis: A Scoping Review of Current Applications and Future Potential in Breast Cancer Research by Redona Brahimetaj, Jan Cornelis, Bart Jansen

“…Further research will solidify its role in clinical practice and potentially expand its applications in breast cancer studies.…”
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The Promise of AI for Image-Driven Medicine: Qualitative Interview Study of Radiologists’ and Pathologists’ Perspectives by Jojanneke Drogt, Megan Milota, Wouter Veldhuis, Shoko Vos, Karin Jongsma

“…ConclusionsThis study points to the importance of maintaining a “healthy skepticism” on the promise of AI in imaging specialisms and argues for more structural and inclusive discussions about whether AI is the right technology to solve current problems encountered in daily clinical practice.…”
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