Citrullinated Antigens with Multiple Citrulline Similar Motif in the Diagnosis of Rheumatoid Arthritis: A Preliminary Single-Center Study by Zhu Chen, Weiting Fang, Yi Qin, Yin-Zhao Jin, Xiang Yang, Jianrong Lou

“…The presence of anti-citrullinated protein antibodies (ACPAs) in the serum is one of the immunological features of rheumatoid arthritis (RA). …”
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Citrulline – The Powerhouse Nutrient for Cardiometabolic and Brain Health by Daria Pedrycz, Mateusz Drabczyk, Emilia Pedrycz, Karolina Karoń, Grzegorz Drapała, Wojciech Grabowski, Łukasz Karoń, Anna Zygmunt, Sławomir Karoń

Subjects: “…Citrulline…”
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An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders by Mohammed Alghamdi, Doaa Alasmari, Amjad Assiri, Ehab Mattar, Abdullah A. Aljaddawi, Sana G. Alattas, Elrashdy M. Redwan

“…A protein undergoes many types of posttranslation modification. Citrullination is one of these modifications, where an arginine amino acid is converted to a citrulline amino acid. …”
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The effects of citrulline supplementation on athlete´s performance: systematic review by Silvia Burgos, Aysu Dursun, Valentin Emilio Fernández Elias

“…This systematic review aims to determine the possible outcomes of L-citrulline of citrulline malate supplementation. Methods: The effects of L-citrulline or Citrulline Malate on trained individuals or professional athletes were examined in a comprehensive literature search using PubMed from 2010 to 2023. …”
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Plasma Citrulline in the Diagnosis and Follow-Up of Celiac Disease by Alicia Isabel Pascual Pérez, Elene Larrea Tamayo, Santiago Jiménez Treviño, David González Jiménez, David Pérez Solís, Cristina Molinos Norniella, Juan José Díaz Martín

Subjects: “…citrulline…”
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L-Citrulline in Neonates: From Bench to Bed Side by Dwayne Mascarenhas, Atefeh Mohammadi, Randa Higazy, Julijana Ivanovska, Estelle Gauda, Bonny Jasani

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Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention by Abdulhakeem Olarewaju Sulyman, Olawale Moshood Aliyu, Emmanuel Oladipo Ajani, Yusuf Folohunsho Abdulkareem, Isaac Ade Afe, Fathia Oluwakemi Abdulyakeen, Halimat Yusuf Lukman, Saheed Sabiu, Karishma Singh, Kuben Naidoo

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Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis by Sunish Mohanan, Brian D. Cherrington, Sachi Horibata, John L. McElwee, Paul R. Thompson, Scott A. Coonrod

“…The peptidylarginine deiminases (PADs) are a family of posttranslational modification enzymes that catalyze the conversion of positively charged protein-bound arginine and methylarginine residues to the uncharged, nonstandard amino acid citrulline. This enzymatic activity is referred to as citrullination or, alternatively, deimination. …”
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Insights to Clinical Use of Serial Determination in Titers of Cyclic Citrullinated Peptide Autoantibodies by Toshiaki Kogure, Takeshi Tatsumi, Hiroshi Fujinaga, Atsushi Niizawa, Katsutoshi Terasawa

“…Anti-cyclic citrullinated peptide (CCP) antibody is a useful marker for the diagnosis and prognosis of rheumatoid arthritis (RA). …”
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Insight into Neutrophil Extracellular Traps through Systematic Evaluation of Citrullination and Peptidylarginine Deiminases by Caitlyn L. Holmes, Daeun Shim, John Kernien, Chad J. Johnson, Jeniel E. Nett, Miriam A. Shelef

“…However, not all NETs are citrullinated. One theory aiming to clarify the intersection of citrullination, NETs, and rheumatoid arthritis suggests that specific stimuli induce different types of NETs defined by citrullination status. …”
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Anti-Cyclic Citrullinated Peptide Antibodies and Severity of Interstitial Lung Disease in Women with Rheumatoid Arthritis by Alberto Daniel Rocha-Muñoz, Manuel Ponce-Guarneros, Jorge Ivan Gamez-Nava, Eva Maria Olivas-Flores, Mayra Mejía, Pablo Juárez-Contreras, Erika Aurora Martínez-García, Esther Guadalupe Corona-Sánchez, Tania Marlen Rodríguez-Hernández, Mónica Vázquez-del Mercado, Mario Salazar-Páramo, Arnulfo Hernan Nava-Zavala, Ernesto German Cardona-Muñoz, Alfredo Celis, Laura González-Lopez

“…To evaluate whether serum titers of second-generation anticyclic citrullinated peptide antibodies (anti-CCP2) are associated with the severity and extent of interstitial lung disease in rheumatoid arthritis (RA-ILD). …”
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Development of Isocratic RP-HPLC Method for Separation and Quantification of L-Citrulline and L-Arginine in Watermelons by Rasdin Ridwan, Hairil Rashmizal Abdul Razak, Mohd Ilham Adenan, Wan Mazlina Md Saad

“…In this study, watermelons grown and consumed in Malaysia were investigated for their amino acid content, L-citrulline and L-arginine, by the isocratic RP-HPLC method. …”
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Porphyromonas gingivalis associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population by Helga Westerlind, Linda Mathsson-Alm, Alexandra Circiumaru, Aase Hensvold, Karin Lundberg, Jan Potempa, Yogan Kisten, Charlotte De Vries, Marina Dehara, Barbara Potempa

“…Objective The antibody response against Porphyromonas gingivalis (Pg) is elevated in rheumatoid arthritis (RA), especially in patients with anti-citrullinated protein antibodies (ACPA). Here, we investigated whether antibodies against the Pg virulence factor arginine gingipain (Rgp) are associated with the RA-risk phase and development of arthritis.Methods At-risk individuals were included in a prospective study (Risk-RA) based on a positive anti-cyclic citrullinated peptide 2 (CCP2) antibody test, and having musculoskeletal complaints but no signs of arthritis. …”
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Clinical utility of anti-cyclic citrullinated peptid and rheumatoid factor in chronic hepatitis B virus infection by Gokhan Sargin, Altay Kandemir

Subjects: “…Anti-cyclic citrullinated…”
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Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture by Tim Ammon, Julia Zeiträg, Vanessa Mayr, Manuela Benedicic, Hans‐Peter Holthoff, Martin Ungerer

“…Objective Rheumatoid arthritis (RA) is characterized by circulating anti–cyclic citrullinated peptide (CCP) autoantibodies (ACPAs), resulting in inflammation of the joints and other organs. …”
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Impact of Likelihood Ratios of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Antibody in Clinical Diagnosis of Rheumatoid Arthritis by Two Available Platforms by Juan Irure-Ventura, María Díaz-Toledo, Noelia Palazuelos-Cayón, Marcos López-Hoyos

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Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D by Yang Qin, Li Liu, Yanwen Zhang, Xiaowei Chen, Jiani Zhang, Sunwang Ling, Jianguang Wang, Xinyu Yang

“…Abstract Protein citrullination modification plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA), and anti-citrullinated protein antibodies (ACPAs) are extensively employed for clinical diagnosis of RA. …”
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Evaluation of a new biomarker 14-3-3 Eta protein in diagnosis of rheumatoid arthritis by Lakshmi Deepika Yarlagadda, Rachel Jacob, D Liza Rajasekhar, Krishna Mohan Iyyapu, Sai Baba S S. Kompella, Vijaya Bhaskar Madrol, N N Sreedevi, Siraj Ahmed Khan, Noorjahan Mohammed

Subjects: “…anti-citrullinated peptide antibodies…”
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Prognostic importance of human leukocyte antigen DRβ1 gene and protein tyrosine phosphatase nonreceptor Type 22 gene polymorphism in rheumatoid arthritis by Pramod Kumar Verma, Usha Singh, Shyam Kumar Saraf, Narendra Kumar Singh

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Revisiting the Link Between HLA‐DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non‐Shared Epitope Alleles *09 and *15 With High Levels of Anti–Citrullinated Peptide/Protein Antibodies by Denis Lagutkin, Luis Panaifo, Ahmad‐Fauzi Nurul‐Aain, Lena Israelsson, Monika Hansson, Karin Lundberg, Lars Alfredsson, Johan Askling, RACI consortium, Lars Klareskog, Chun‐Lai Too, Leonid Padyukov

“…We focused on a quantitative analysis of the levels of anti–cyclic citrullinated peptide IgG antibodies, including those falling below the diagnostic threshold. …”
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