Causes and Clinical Profiles of Ascites at University of Gondar Hospital, Northwest Ethiopia: Institution-Based Cross-Sectional Study by Oumer Abdu Muhie

“…The other main causes of ascites were heart failure from various causes (19.2%), tuberculosis and hepatosplenic schistosomiasis contributing to 11.5% each and chronic kidney disease (5.8%). Five (20.8%) CLD patients had spontaneous bacterial peritonitis as a complication. …”
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Sex-specific differences in the efficacy of renal denervation in patients with resistant hypertension depending on visceral obesity and kidney function by Irina Zyubanova, Nadezhda Ryumshina, Victor Mordovin, Musheg Manukyan, Valeriya Lichikaki, Ekaterina Solonskaya, Anna Gusakova, Tatjana Suslova, Stanislav Pekarskiy, Simzhit Khunkhinova, Anastasia Popova, Veronika Rudenko, Alla Falkovskaya

“…In women, the eGFR remained unchanged only in those with chronic kidney disease (CKD) (n = 10) and decreased in the absence of CKD (n = 23) from 79.7 ± 14.1 to 72.1 ± 12.0 ml/min/1.73 m2 (p = 0.011). …”
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Impact of Moderate to Severe Renal Impairment on Mortality and Appropriate Shocks in Patients with Implantable Cardioverter Defibrillators by Venkata M. Alla, Kishlay Anand, Mandeep Hundal, Aimin Chen, Showri Karnam, Tom Hee, Claire Hunter, Aryan N. Mooss, Dennis Esterbrooks, Syed M. Mohiuddin

“…Due to underrepresentation of patients with chronic kidney disease (CKD) in large Implantable-Cardioverter Defibrillator (ICD) clinical trials, the impact of ICD remains uncertain in this population. …”
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A Single Lung Transplant in a Patient with Fabry Disease: Causality or Far-Fetched? A Case Report by Martina Gaggl, Renate Kain, Peter Jaksch, Dominik Haider, Gerald Mundigler, Till Voigtländer, Raute Sunder-Plassmann, Paulus Rommer, Walter Klepetko, Gere Sunder-Plassmann

“…Overall, the patient might have benefited from specific enzyme replacement therapy, especially in view of the chronic kidney disease.…”
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Glycogen Storage Disease Type Ia: A Retrospective Claims Analysis of Complications, Resource Utilization, and Cost of Care by Eliza Kruger, Justin Nedzesky, Nina Thomas, Jeffrey D. Dunn, Andrew A. Grimm

“…Chronic complications (eg, gout, osteoarthritis, chronic kidney disease, and neoplasms) were more common in adults with GSDIa, whereas acute complications (eg, poor growth, gastrostomy, seizure, and hypoglycemia) were more common in children with GSDIa. …”
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Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease by Brandon Zimmerman, Leslie A. Dakin, Anne Fortier, Evanthia Nanou, Angelo Blasio, James Mann, Howard Miller, Marissa Fletcher, Tiansheng Wang, Suganthini Nanthakumar, Gizelle McCarthy, Caline Matar, Prachi Matsye, Guanyu Wang, Phillip Snyder, Kevin Daniel, Harsha Swamy, Kelly Sullivan, Franklin Bright, Audrey Powers, Kevin J. Gagnon, Fan Lu, Steven Paula, Suvarna Khare-Pandit, Larry Henry, Martine Hamel, Francois Denis, Olivier Nicolas, Niresh Hariparsad, Shyamesh Kumar, Jennifer Proctor, Timothy Senter, Brinley Furey, Mark E. Bunnage

“…Abstract Chronic kidney disease affects ~10% of people worldwide and there are no disease modifying therapeutics that address the underlying cause of any form of kidney disease. …”
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Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease by Silvia Lucisano, Adriana Arena, Giovanna Stassi, Daniela Iannello, Gaetano Montalto, Adolfo Romeo, Giuseppe Costantino, Rosaria Lupica, Valeria Cernaro, Domenico Santoro, Michele Buemi

“…Methods. 40 patients with end-stage chronic kidney disease (CKD) and secondary hyperparathyroidism and 40 healthy subjects were enrolled. …”
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GPX4 expression changes in proximal tubule cells highlight the role of ferroptosis in IgAN by Jianbo Qing, Lijuan Zhang, Ru Fan, Huiwen Zhi, Changqun Li, Yaheng Li, Junnan Wu, Chongyang Han, Yafeng Li

“…However, the contribution of OS to IgA nephropathy (IgAN), the primary driver of chronic kidney disease remains uncertain. To investigate the effects of OS in IgAN, and identify the mechanisms of cell and tissue injury and protection, single-cell RNA sequencing (scRNA-seq) data and microarray data of IgAN were collected and analyzed. …”
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Predicting exacerbation of renal function by DNA methylation clock and DNA damage of urinary shedding cells: a pilot study by Akihito Hishikawa, Erina Sugita Nishimura, Norifumi Yoshimoto, Ran Nakamichi, Eriko Yoshida Hama, Wataru Ito, Tomomi Maruki, Kengo Nagashima, Ryoko Shimizu-Hirota, Hiromasa Takaishi, Hiroshi Itoh, Kaori Hayashi

“…This study suggests the potential role of the DNA methylation clock and urinary DNA damage as predictive markers for the progression of chronic kidney disease.…”
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بررسی ارتباط شدت سندرم پای بی‌قرار با نوع دیالیز و شاخص‌های خونی کلسیم، فسفر، هورمون پاراتیروئید و ویتامین D... by الهام بابائی, سحر وحدت

“…مقاله پژوهشی مقدمه: سندرم پای بی‌قرار (Restless leg syndrome) RLS یک عارضه‌ی شایع در در بیماری مزمن کلیه (Chronic kidney disease) CKD است. با توجه به مبهم بودن پاتوفیزیولوژی این عارضه، تأثیر روش دیالیز و ارتباط بین سطح سرمی پارامترهای خونی در شدت بروز RLS به خوبی مشخص نشده است. …”
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The utility of split function testing in determining recovery of glomerular filtration rate after living kidney donation: a cohort study by Kirsty J. Crowe, Siobhan K. McManus, Julie A. Glen, Karen S. Stevenson, Ian M. McLaughlin, Alice Nicol, Colin C. Geddes

“…Univariable and multivariable linear regression analysis was used to analyse the impact of donor factors on recovery of renal function at one year relative to baseline isotope GFR (iGFR) or to estimated GFR (eGFR by Chronic Kidney Disease Epidemiology Collaboration [CKD-EPI] formula). …”
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Kidney disease among adults on tenofovir-based second-line antiretroviral therapy in Dar es Salaam, Tanzania by Sabina F. Mugusi, Grace A. Shayo, Philip G. Sasi, Lulu S. Fundikira, Eric A. Aris, Christopher R. Sudfeld, Ferdinand M. Mugusi

“…Tenofovir disoproxil fumarate (TDF) can result in proximal tubulopathy and acute tubular injury, whereas atazanavir/ritonavir (ATV/r) can cause interstitial nephritis and renal stones, both of which can lead to chronic kidney disease. Objectives: To examine the relationship between second-line combination antiretroviral therapy (ART) and the risk of kidney disease and morphological changes among PLWH in Dar es Salaam, Tanzania. …”
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Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate by Xueting Qi, Jingjing Wang, Tong Wang, Weijing Wang, Dongfeng Zhang

“…These findings provided new insights into the epigenetic modifications related to the decline in eGFR and chronic kidney disease.…”
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Safety and Efficacy of Second-Generation Drug-Eluting Stents in Real-World Practice: Insights from the Multicenter Grand-DES Registry by You-Jeong Ki, Kyung Woo Park, Jeehoon Kang, Chee-Hoon Kim, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim

“…In the multivariate analysis, chronic kidney disease was the strongest predictor of stent thrombosis (adjusted hazard ratio 3.178; 95% confidence interval 1.621–6.229; P<0.001). …”
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Can Underlying Co-Morbidities Affect Cerebral Oximetry in Cardiac Surgery Patients? by Kianoush Saberi, Shahnaz Sharifi, Amirhossein Orandi

“…To add details, according to literatures about CVA 28% of patients had (Cerebrovascular Accident), 74% IHD (Ischemic Heart Disease), 82% HTN (Hypertension), 52% DM (Diabetes Mellitus), 61% Smoking History, 36% CKD (Chronic Kidney Disease) and 42% CHF (Congestive Heart Failure). …”
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The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice by Li Li, Jun Li, Hui Xu, Fengmei Zhu, Zhijun Li, Hongzhi Lu, Jinrong Zhang, Zhengsheng Yang, Yongsheng Liu

“…Ischemia acute kidney injury is a significant risk in developing progressive and deterioration of renal function leading to clinic chronic kidney disease. There were many attempts to protect the kidney against this progression of renal damage. …”
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Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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Prognostic role of aetiological agent vs. clinical pattern in candidates to lead extraction for cardiac implantable electronic device infections by Giulia Massaro, Renato Pascale, Mauro Biffi, Cristian Martignani, Matteo Ziacchi, Andrea Simeone, Raimondo Pittorru, Manuel De Lazzari, Federico Migliore, Igor Diemberger

“…S. aureus was isolated in 32.5% of patients, and it was more associated with valvular heart disease, systemic infection, and chronic kidney disease. CIEDI pattern was associated with 1-year mortality, with a significantly worse outcome in patients with “cold closed pocket” (CCP). …”
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Poor Glycemic Control in Carbapenem-Resistant Klebsiella pneumoniae Infections: Impact on Epidemiological Features, Mortality Risks, and Polymyxin Resistance by Wang Q, Yan T, Ma C, Teng X, Shen C, Wang N, Yu K, Chu W, Zhou Q, Liu Z

“…Three clinically isolated CRKP strains were used to investigate the effect of glucose on bacterial capsule synthesis and the impact on bacterial resistance to polymyxin and serum killing.Results: Patients with poor glycemic control experienced more severe infections and had a higher likelihood of chronic kidney disease (CKD) and acute renal insufficiency compared to those with good glycemic control. …”
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Targeting ASK1 by CS17919 alleviates kidney‐ and liver‐related diseases in murine models by Guoqiang Liao, Qianjiao Yang, Xuhua Mao, Yiru Zhao, Beizhong Chen, Kun Zhang, Yu Zhang, Ping Zhang, Zhengli Chen, Shengjian Huang

“…Finally, we tested the in vivo efficacy of CS17919 in murine models of chronic kidney disease (CKD) and non‐alcoholic steatohepatitis (NASH). …”
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