Impact of variables on recovery time in patients undergoing hemodialysis: an international survey by Nurten Ozen, Tayfun Eyileten, Paulo Teles, Baris Seloglu, Ayse Gurel, Aysegul Ocuk, Volkan Ozen, Filipa Fernandes, Luís Campos, Sara Coutinho, Joana Teixeira, Sandra Cristina Mendo Moura, Olga Ribeiro, Clemente Neves Sousa

“…This study aimed to identify the factors influencing DRT in hemodialysis patients in Turkey and Portugal, where the prevalence of chronic kidney disease is notably high. Methods A cross-sectional observational study was conducted in a private dialysis center in Turkey and three dialysis centers in Portugal. …”
Get full text

Optimization of 25% Sulfosalicylic Acid Protein-to-Creatinine Ratio for Screening of Low-Grade Proteinuria by Ambulugala Gamage Rajika Greshamali Jinadasa, Lanka Acharige Shalka Madushan Srimantha, Indika Deepani Siriwardhana, Kalani Buddika Gunawardana, Anoja Priyadarshani Attanayake

“…In phase II, clinical applicability of the optimized method was evaluated using retained urine samples of patients with chronic kidney disease (CKD) assessed for urine protein by the pyrogallol red (PGR) method in a tertiary care hospital in Sri Lanka. …”
Get full text

Pulmonary Mucormycosis – An Experience from a Tertiary Care Center in Southern India: A PULM MUCOR Study by Ashwin Oliver Arul, K. Rajiv Karthik, Devasahayam Jesudas Christopher

“…Uncontrolled diabetes mellitus and chronic kidney disease were the conventional predisposing factors for pulmonary mucormycosis. …”
Get full text

The temporal relationship between mitochondrial quality and renal tissue recovery following ischemia-reperfusion injury by Priyanka N. Prem, Harish Swaminathan, Gino A. Kurian

“…Background: Growing evidence indicates that disruptions in mitochondrial quality management contribute to the development of acute kidney injury (AKI), incomplete or maladaptive kidney repair, and chronic kidney disease. However, the temporal dynamics of mitochondrial quality control alterations in relation to renal injury and its recovery remain poorly understood and are addressed in this manuscript. …”
Get full text

Astragaloside IV attenuates cadmium induced nephrotoxicity in rats by activating Nrf2 by Yuchen Li, Jiayi Zhou, Tianxin Zhang, Xiaocong Li, Cheng Wu, Ziyi Zhao, Jianyuan Tang, Xiaoyu Tan, Qiongying Hu, Wenhao Liao

Get full text

Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids by Taisuke Furusho, Ranjan Das, Hideyuki Hakui, Anusha Sairavi, Kei Adachi, Mia S. Galbraith-Liss, Pratheppa Rajagopal, Masahiro Horikawa, Shuhua Luo, Lena Li, Kentaro Yamada, Nicole Andeen, Gregory A. Dissen, Hiroyuki Nakai

“…We find that local delivery of AAV-KP1, but not AAV9, via the renal vein or pelvis effectively transduces proximal tubules with minimal off-target liver transduction, while systemic AAV9, but not AAV-KP1, enhances proximal tubule and podocyte transduction in chronic kidney disease. We demonstrate that these contrasting observations are partly due to differences in their pharmacokinetics. …”
Get full text

Role of colour doppler ultrasound in the evaluation of hemodialysis arteriovenous access maturation and its correlation with success rate by Alka Agrawal, Prachi Shukla, Mayank Patidar, Suhas Kattigowda

“…Background: Chronic kidney disease (CKD) is a significant global health issue, with many patients with end-stage renal disease (ESRD) requiring hemodialysis. …”
Get full text

Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG by Silvija Valdonė Alšauskė, Ingrida Grabauskytė, Ida Liseckienė, Jūratė Macijauskienė

“…Statistically significant associations were found between cognitive impairment and chronic obstructive pulmonary disease (COPD) (<i>p</i> = 0.008 and <i>p</i> = 0.003) in both tests and chronic kidney disease (CKD) (<i>p</i> = 0.005) while testing with the MMSE. …”
Get full text

Safety and Biodistribution of an Autologous Bone Marrow-Derived Mononuclear Cell Infusion into Renal Arteries in Patients with Focal Segmental Glomerulosclerosis: A Phase 1 Study by Bruno Freire Botelho, André Luis Barreira, Marcio Gomes Filippo, Karina Dutra Asensi, Lanuza A P Faccioli, Anna Beatriz dos Santos Salgado, Elizabeth Figueiredo de Salles, Carlos Eduardo Cruz Marques, Pedro Leme Silva, Regina Coeli dos Santos Goldenberg, Angelo Maiolino, Bianca Gutfilen, Sergio Augusto Lopes de Souza, Maurilo Leite Junior, Marcelo Marcos Morales

“…Patients with focal segmental glomerulosclerosis (FSGS) who are refractory to drug treatment may present progressive loss of kidney function, leading to chronic kidney disease stage 5 under dialysis treatment. The safety of systemic administration of bone marrow-derived mononuclear cells (BMDMCs) has been shown in different preclinical models of kidney diseases. …”
Get full text

Comparative safety and effectiveness of oral anticoagulants in key subgroups of patients with non-valvular atrial fibrillation and at high risk of gastrointestinal bleeding: A coho... by Gregory Y H Lip, Robert Benamouzig, Anne-Céline Martin, Giancarlo Pesce, Gaelle Gusto, Nadia Quignot, Artak Khachatryan, Feng Dai, Fouad Sedjelmaci, Jose Chaves, Rupesh Subash, Ruth Mokgokong

“…The following subgroups were evaluated: patients age ≥75 years, receiving concomitant medications, HAS-BLED score ≥3, and chronic kidney disease stage 3-4. Outcomes included major bleeding and stroke/systemic embolism. …”
Get full text

Urological, vascular, and infectious implications of kidney transplant: a single-center experience by Juan G. Prada, Sofía Manjarrés-Sierra, Isabella Lince-Rivera, Carolina Martínez-Pinedo, Carolina Martínez-Pinedo, Germán Patiño, Hugo E. López

“…The most common chronic kidney disease etiologies were: idiopathic (25.5%), glomerulopathies (24.7%), and hypertension (23.5%). …”
Get full text

Factors Associated with Visit-to-Visit Variability of Blood Pressure Measured as Part of Routine Clinical Care among Patients Attending Cardiology Outpatient Department of a Tertia... by Thirunavukarasu Kumanan, Vathulan Sujanitha, Mahesan Guruparan, Nadarajah Rajeshkannan

“…When comparing mean SD among the categories of different variables, female sex (P=0.023) and comorbidities such as diabetes mellitus (DM) (P=0.013), chronic kidney disease (CKD) (P=0.007), and risk of developing obstructive sleep apnoea (OSA) (P=0.04) showed significant variation. …”
Get full text

Possible Threats of IgA Vasculitis in Children: One Center Experience by Eglė Lanzbergaitė-Manuilova, Skirmantė Rusonienė, Augustina Jankauskienė

“…There were no bad outcomes: lethal outcome or chronic kidney disease for the patients with GI and kidney involvement in recent study. …”
Get full text

The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo by Jacob Schade Engbjerg, Vincenzo Costanzo, Donato Sardella, Luca Bordoni, Steen Jakobsen, Luciano D'Apolito, Jørgen Frøkiær, Francesco Trepiccione, Giovambattista Capasso, Sebastian Frische

“…Accumulation of uremic toxins may lead to the life-threatening condition “uremic syndrome” in patients with advanced chronic kidney disease (CKD) requiring renal replacement therapy. …”
Get full text

IVUS-Guided Zero-Contrast PCI in CKD Patients: Safety and Short-Term Outcome in Patients with Complex Demographics and/or Lesion Characteristics by Prathap Kumar, Blessvin Jino, Ali Shafeeq, Stalin Roy, Manu Rajendran, Sandheep George Villoth

“…To assess the safety and short-term outcomes of IVUS-guided zero-contrast PCI in chronic kidney disease (CKD) patients with complex demographics or lesion morphology. …”
Get full text

Long-Term Outcomes of Coronary and Carotid Artery Disease Revascularization in the FRIENDS Study by Fabrizio Tomai, Anna Piccoli, Fausto Castriota, Luca Weltert, Bernhard Reimers, Gabriele Pesarini, Raoul Borioni, Giovanni De Persio, Roberto Nerla, Andrea Pacchioni, Alberto Cremonesi, Flavio Ribichini

“…However, the hybrid group exhibited rates of myocardial infarction, chronic kidney disease, and cumulative incidence of all clinical events higher than the surgical group. …”
Get full text

Monitoring for 5-aminosalicylate nephrotoxicity in adults with inflammatory bowel disease: prognostic model development and validation using data from the Clinical Practice Researc... by Abhishek Abhishek, Richard D Riley, Christian D Mallen, Guruprasad P Aithal, Georgina Nakafero, Matthew J Grainge, Maarten W Taal, Tim Card, Matthew D Stevenson

“…Nine predictors were included in the final model, including chronic kidney disease stage 3 and hazardous alcohol use as strong predictors. …”
Get full text

Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association... by Tiago Alfaro, Filipe Froes, Cláudia Vicente, Rui Costa, Cristina Gavina, Rui Baptista, António Maio, Saraiva da Cunha, João Sérgio Neves, Pedro Leuschner, Sofia Duque, Paula Pinto

“…Background Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.Methods Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine endorses this position paper with recommendations to prevent RSV-associated disease and its complications in adults through vaccination.Conclusion The RSV vaccine is recommended for people aged ≥50 years with risk factors (chronic obstructive pulmonary disease, asthma, heart failure, coronary artery disease, diabetes, chronic kidney disease, chronic liver disease, immunocompromise, frailty, dementia, and residence in a nursing home) and all persons aged ≥60 years. …”
Get full text

Acute kidney injury in patients with COVID-19 in the intensive care unit: evaluation of risk factors and mortality in a national cohort by Pål Klepstad, Eirik Aasen Aukland, Stein Magnus Aukland, Fatemeh Zamanzad Ghavidel, Eirik Alnes Buanes

“…Patients with chronic kidney disease (CKD) were excluded in order to avoid bias from CKD on the incidence of AKI.Primary and secondary outcome measures Primary outcome was AKI at ICU admission as defined by renal Simplified Acute Physiology Score in NIPaR. …”
Get full text

The Application of Incretin-Based Pharmacotherapy in the Contemporary Management of Type 2 Diabetes: A Review of the Literature by Jakub Waszczyński, Wojciech Kulej, Wiktor Biesiada, Piotr Kulej, Justyna Woźniak, Justyna Weronika Kmieć, Anna Mariia Chernysh, Aleksandra Dusińska, Kamila Fuczyło, Karolina Stankević

“… Introduction Type 2 diabetes is a critical global health issue due to its rising prevalence and severe complications, including cardiovascular diseases, chronic kidney disease, and neuropathies, which reduce quality of life and increase mortality risk. …”
Get full text