Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome by Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, Leslie A. Mitchell, Jef D. Boeke, Thomas C. Williams, Ian T. Paulsen, Isak S. Pretorius

“…Abstract The Sc2.0 global consortium to design and construct a synthetic genome based on the Saccharomyces cerevisiae genome commenced in 2006, comprising 16 synthetic chromosomes and a new-to-nature tRNA neochromosome. …”
Get full text

Evaluation of Associated Structural and Chromosomal Abnormalities in Patients with Fetal Cerebral Ventriculomegaly Detected in Ultrasonographic Imaging by Erkan Cagliyan, Samican Ozmen, Sureyya Saridas Demir, Ceren Aydin, Egehan Bilen, Handan Guleryuz, Elif Yasar, Derya Ercal, Elcin Bora, Tufan Cankaya

“…Invasive prenatal tests were performed on 27 patients and one of them had a chromosomal abnormality. No significant correlation was observed between the incidence of postpartum neurodevelopmental disorders and the degrees of ventriculomegaly. …”
Get full text

Identification of univalent chromosomes in monosomic lines of cotton (Gossypium hirsutum L.) by means of cytogenetic markers by M. F. Sanamyan, Sh. U. Bobokhujayev

Subjects: Get full text

Genetic Instability Promotes the Acquisition of Chromosomal Imbalances in T1b and T1c Breast Adenocarcinomas by Harald Blegen, B. Michael Ghadimi, Annukka Jauho, Anders Zetterberg, Elina Eriksson, Gert Auer, Thomas Ried

“…Larger tumor size correlated with an increasing number of chromosomal copy number changes and in particular with regional amplifications. …”
Get full text

Artemisinin-Based Combination Therapy Depressed Mitosis and Induced Chromosome Aberration in Onion Root Cells by J. I. Raji, C. K. Onwuamah, P. G. C. Odeigah

“…The toxicity on the mitotic index varies with the duration of exposure and dose tested. Chromosome aberrations observed include chromosome fragments, chromosome bridges, binucleated cells, and micronucleated cells. …”
Get full text

A New Multiple-Distribution GAN Model to Solve Complexity in End-to-End Chromosome Karyotyping by Yirui Wu, Xiao Tan, Tong Lu

“…An end-to-end chromosome karyotype analysis system is proposed over medical big data to automatically and accurately perform chromosome related tasks of detection, segmentation, and classification. …”
Get full text

Real-time analysis of initiation regulation systems during the progression of the reconstituted chromosomal replication cycle by Koki Kanoh, Masayuki Su’etsugu

Subjects: Get full text

A state-of-art review of Loricariidae (Ostariophysi: Siluriformes) cytogenetics by Francisco de Menezes Cavalcante Sassi, Marcelo de Bello Cioffi, Orlando Moreira-Filho

Subjects: Get full text

Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population by L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk

Subjects: “…azfc deletions of the y chromosome…”
Get full text

An Unsuspected Finding of t(9;22): A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma by Prajwal Boddu, C. Cameron Yin, Rashmi Kanagal-Shamanna, Guillin Tang, Beenu Thakral, Tapan Kadia, Marina Konopleva, Elias Jabbour, Nitin Jain

Get full text

Chromosome-level genome assembly of black carp Mylopharyngodon piceus using Nanopore and Hi-C technologies by Yuxuan Zhang, Yanwen Shao, Xudong Liu, Liang Zhong, Zhaoyan Zhong, Weiwei Zeng, Jiping Zhang, Wenlong Cai, Runsheng Li

“…In this study, we aimed to generate a high-quality chromosome-level genome assembly of black carp using Nanopore and Hi-C technologies. …”
Get full text

METTL16 is Required for Meiotic Sex Chromosome Inactivation and DSB Formation and Recombination during Male Meiosis by Lisha Yin, Nan Jiang, Wenjing Xiong, Shiyu Yang, Jin Zhang, Mengneng Xiong, Kuan Liu, Yuting Zhang, Xinxin Xiong, Yiqian Gui, Huihui Gao, Tao Li, Yi Li, Xiaoli Wang, Youzhi Zhang, Fengli Wang, Shuiqiao Yuan

“…Here, we report an essential role of the m6A methyltransferase METTL16 in meiotic sex chromosome inactivation (MSCI), double‐strand break (DSB) formation, homologous recombination and SYCP1 deposition during male meiosis. …”
Get full text

A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity by Sandra J. Hasstedt, Yuanpei Xin, Rong Mao, Tracey Lewis, Ted D. Adams, Steven C. Hunt

“…One or more of 7 genes residing in a chromosome 20q13.3 CNV region appears to influence BMI. …”
Get full text

Ring Chromosome 4 in a Child with Multiple Congenital Abnormalities: A Case Report and Review of the Literature by C. S. Paththinige, N. D. Sirisena, U. G. I. U. Kariyawasam, L. P. C. Saman Kumara, V. H. W. Dissanayake

“…Clinical features observed in this case are consistent with the consensus phenotype in ring chromosome 4. Patent ductus arteriosus and bilateral talipes equinovarus observed in this baby widen the phenotypic spectrum associated with ring chromosome 4.…”
Get full text

Cytogenomic Characterization of Giant Ring or Rod Marker Chromosome in Four Cases of Well-Differentiated and Dedifferentiated Liposarcoma by Hongyan Chai, Fang Xu, Autumn DiAdamo, Brittany Grommisch, Huanzhi Mao, Peining Li

“…The results revealed the characteristic giant ring (GR) or giant rod marker (GRM) chromosomes in all four cases and amplification of numerous somatic copy number alterations (SCNAs) involving a core segment of 12q14.1q15 and other chromosomal regions in three cases. …”
Get full text

Evaluations of Auto-Focusing Methods under a Microscopic Imaging Modality for Metaphase Chromosome Image Analysis by Yuchen Qiu, Xiaodong Chen, Yuhua Li, Wei R. Chen, Bin Zheng, Shibo Li, Hong Liu

“…Although many auto-focusing methods have been developed and tested for a variety of imaging modalities, few investigations have been performed on the selection of an optimal auto-focusing method that is suitable for the pathological metaphase chromosome analysis under a high resolution scanning microscopic system.…”
Get full text

A variant W chromosome in Centromochlus heckelii (Siluriformes, Auchenipteridae) and the role of repeated DNA in its heteromorphism by Chrystian Aparecido Grillo Haerter, Patrik Ferreira Viana, Fábio Hiroshi Takagui, Sandro Tonello, Vladimir Pavan Margarido, Daniel Rodrigues Blanco, Josiane Baccarin Traldi, Roberto Laridondo Lui, Eliana Feldberg

Subjects: Get full text

EFFECT OF CERTAIN CHROMOSOME REGIONS OF TRITICUM TIMOPHEEVII ON THE FORMATION OF PEST RESISTANCE AND QUANTITATIVE TRAITS IN COMMON WHEAT by E. M. Timonova, I. N. Leonova, I. A. Belan, L. P. Rosseeva, E. A. Salina

“…In addition, positive effect of the 2G chromosome fragments of Triticum timopheevii on ear grain number was established. …”
Get full text

Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients by Minjie Li, Yu Gao, Lin Han, Ping Wang, Jie Li, Junhua Song, Shasha Du, Yunfei Zhang, Yumin Lyu

Subjects: Get full text

Traces of Paleolithic expansion in the Nivkh gene pool based on data on autosomal SNP and Y chromosome polymorphism by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, A. L. Sukhomyasova, I. Yu. Khitrinskaya, V. A. Stepanov

Subjects: Get full text