The DNA Replication Stress Hypothesis of Alzheimer’s Disease by Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov

“…Vulnerable neurons of the AD brain exhibit biomarkers of cell cycle progression and DNA replication suggesting a reentry into the cell cycle. Chromosome reduplication without proper cell cycle completion and mitotic division probably causes neuronal cell dysfunction and death. …”
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Systemic lupus erythematosus in a patient with 22q11.2 deletion syndrome: A case report and review of the literature by Chen Sun, Pingyang Han, Juzhen Yan

“…22q11.2 deletion syndrome (MIM: 192430/188400, ORPHA: 567) is the most common chromosomal microdeletion disorder, caused by a hemizygous microdeletion of 2.5 million base pairs on chromosome 22. …”
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Raise of short-stemmed vaviloid branched spike lines and their cytogenetics by A. J. Aliyeva, S. P. Mehdiyeva, R. K. Kerimova

“…Chromosomal identification of such lines will allow their use in genetic studies concerning specified traits, in particular, the vaviloid branched spike.…”
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12q14 Microdeletions: Additional Case Series with Confirmation of a Macrocephaly Region by Adrian Mc Cormack, Cynthia Sharpe, Nerine Gregersen, Warwick Smith, Ian Hayes, Alice M. George, Donald R. Love

“…To date, there have been only a few reports of patients carrying a microdeletion in chromosome 12q14. These patients usually present with pre- and postnatal growth retardation, and developmental delay. …”
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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy by Monika Podhorecka, Andrzej Skladanowski, Przemyslaw Bozko

“…Double-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. …”
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Urinary Catheter Colonization by Multidrug-Resistant Cedecea neteri in Patient with Benign Prostatic Hyperplasia by Peter S. Ginn, Serina B. Tart, Stephen M. Sharkady, Dorothea K. Thompson

“…Analysis of whole genome sequence information for a representative C. neteri strain indicated the presence of multiple open reading frames with sequence similarity to β-lactamases, including a chromosome-encoded AmpC β-lactamase and metallo-β-lactamases, consistent with the resistance phenotype of this bacterium. …”
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Effects of Bile Acids and Nisin on the Production of Enterotoxin by Clostridium perfringens in a Nutrient-Rich Medium by Miseon Park, Fatemeh Rafii

“…The effects of low concentrations of nisin and bile acids on sporulation and toxin production were investigated in C. perfringens SM101, which carries an enterotoxin gene on the chromosome, in a nutrient-rich medium. Bile acids and nisin increased production of enterotoxin in cultures; bile acids had the highest effect. …”
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Prediction of Chaotic Time Series Based on BEN-AGA Model by LiYun Su, Fan Yang

“…The weights to be optimized in the model are coded as chromosomes. We design the dynamic crossover probability and mutation probability to control the crossover process and the mutation process, and the optimal parameters are selected through the fitness function to evaluate the chromosome. …”
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Acute Myeloid Leukemia with Basophilic Differentiation Transformed from Myelodysplastic Syndrome by Yasuhiro Tanaka, Atsushi Tanaka, Akiko Hashimoto, Kumiko Hayashi, Isaku Shinzato

“…An 81-year-old man was referred to our department for further examination of intermittent fever and normocytic anemia during immunosuppressive treatment. Chromosomal analysis showed additional abnormalities involving chromosome 7. …”
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Helicobacter pylori Infection, Chronic Inflammation, and Genomic Transformations in Gastric MALT Lymphoma by Magdalena Witkowska, Piotr Smolewski

“…This group has often a chromosome translocation, which suggests that there is another unknown, so far, pathogenetic mechanism of MALT lymphoma. …”
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IL-32: A Novel Pluripotent Inflammatory Interleukin, towards Gastric Inflammation, Gastric Cancer, and Chronic Rhino Sinusitis by Muhammad Babar Khawar, Muddasir Hassan Abbasi, Nadeem Sheikh

“…The IL-32 gene was identified on human chromosome 16 p13.3. The gene has eight exons and nine splice variants, namely, IL-32α, IL-32β, IL-32γ, IL-32δ, IL-32ε, IL-32ζ, IL-32η, IL-32θ, and IL-32s. …”
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The genetic architecture of resistance to flubendiamide insecticide in Helicoverpa armigera (Hübner). by Douglas Amado, Eva L Koch, Erick M G Cordeiro, Wellingson A Araújo, Antonio A F Garcia, David G Heckel, Gabriela Montejo-Kovacevich, Henry L North, Alberto S Corrêa, Chris D Jiggins, Celso Omoto

“…Both approaches identified one locus on chromosome 2, revealing two SNPs within 976 bp that can be used to monitor field resistance to flubendiamide. …”
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Assessment of Cytogenotoxicity of Plastic Industrial Effluent Using Allium cepa Root Tip Cells by Jibril Sani Mohammed, Yahaya Mustapha, Madu Abdulkarim Him, Zandam Nuhu Danladi

“…With rising effluent concentrations, the mitotic index (M.I.) rapidly dropped. Chromosomal abnormalities were caused by the plastic effluent in the root cells of Allium cepa, especially sticky chromosome and binucleated cells being the most frequently seen at lower concentrations of 15%. …”
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Effects of subclinical hypothyroidism during pregnancy on mtDNA methylation in the brain of rat offspring by Liangzhuo Xie, Yangling Huang, Xiande Ma, Xiaoqiu Ma, Jian Wang, Tianshu Gao, Wei Chen

“…Results In the analysis of differentially methylated regions (DMRs), the mitochondrial chromosome in the SCH group exhibited 23 DMRs compared to the control group. …”
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Diabetic Ketoacidosis in Klinefelter Syndrome Sans Malignancy with Unusually Elevated Levels of CEA: A Case Report by Wo X, Yu X, Miao L, Mao Y, Tang K

“…Xinxin Wo, Xiaoyan Yu, Lingling Miao, Yushan Mao, Keke Tang Department of Endocrinology, The First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, People’s Republic of ChinaCorrespondence: Keke Tang, Department of Endocrinology, The First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, People’s Republic of China, Email lcyxtkk@126.comPurpose: Klinefelter’s syndrome (KS) is the most common sex chromosome disorder in the male population and is characterized by the presence of one or more X chromosomes. …”
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Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation by Håkon Reikvam, Jørn Skavland, Stein-Erik Gullaksen, Randi Hovland, Tobias Gedde-Dahl, Øystein Bruserud, Bjørn Tore Gjertsen

“…Chronic myeloid leukemia (CML) is a myeloproliferative disorder in which neoplastic cells exhibit the Philadelphia chromosome and the related oncoprotein BCR-ABL1. Allogeneic stem cell transplantation (allo-SCT) was considered the first-line treatment for CML, before the introduction of tyrosine kinase inhibitors (TKIs). …”
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Characterization of Erythromycin and Tetracycline Resistance in Lactobacillus fermentum Strains by Elizaveta Anisimova, Dina Yarullina

“…PCR screening for antibiotic resistance determinants revealed plasmid-located tetracycline resistance genes tet(K) and tet(M) in all strains and erythromycin resistance genes erm(B) in the chromosome of L. fermentum 5-1 and erm(C) in the plasmid of L. fermentum 3-4. …”
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The clove (Syzygium aromaticum) genome provides insights into the eugenol biosynthesis pathway by Sonia Ouadi, Nicolas Sierro, Simon Goepfert, Lucien Bovet, Gaetan Glauser, Armelle Vallat, Manuel C. Peitsch, Felix Kessler, Nikolai V. Ivanov

“…Here, we present a 370-Mb high-quality chromosome-scale genome assembly for clove. Comparative genomic analysis between S. aromaticum and Eucalyptus grandis—both species of the Myrtaceae family—reveals good genome structure conservation and intrachromosomal rearrangements on seven of the eleven chromosomes. …”
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Development of a set of monosomic alien addition lines from Gossypium raimondii in Gossypium hirsutum toward breeding applications in cotton by Zhenzhen Xu, Xiaoxi Lu, Wenjie Ding, Wei Ji, Wuzhimu Ali, Heyang Wang, Shan Meng, Qi Guo, Peng Xu, Xianglong Chen, Liang Zhao, Huan Yu, Xinlian Shen

“…Analysis of its mitotic metaphase plates revealed the presence of 78 chromosomes, with each of the six chromosome-specific fluorescence in situ hybridization (FISH) probes (3D5, 5D5, 6D5, 7D5, 9D5, and 10D5) of G. raimondii exhibiting bright and distinct signals on its respective pair of chromosomes. …”
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Delineation of the Genetic Architecture and Clinical Polymorphism of 3q29 Duplication Syndrome: A Review of the Literature and a Report of Two Novel Patients With Single‐Gene BDH1... by A. A. Kashevarova, M. E. Lopatkina, O. Yu. Vasilyeva, D. A. Fedotov, A. D. Lobanov, E. A. Fonova, I. Z. Zhalsanova, A. A. Zarubin, O. A. Salyukova, E. O. Belyaeva, V. V. Petrova, E. G. Ravzhaeva, A. A. Agafonova, A. D. Cheremnykh, N. B. Torkhova, S. L. Vovk, I. N. Lebedev

“…ABSTRACT Background Chromosome 3q29 duplication syndrome is a rare chromosomal disorder with a frequency of 1:5000 in patients with a neurodevelopmental phenotype. …”
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