BLINATUMOMAB IN THE THERAPY OF ACUTE B-LYMPHOID LEUKEMIA by Ugo Testa, Elvira Pelosi, Germana Castelli, Patrizia Chiusolo

“…Furthermore, recent studies in newly diagnosed B-ALL patients have led in Philadelphia chromosome-positive patients to the development of chemotherapy-free regimens based on tyrosine kinase inhibitors plus Blinatumomab and in Philadelphia chromosome-negative patients to improvement in outcomes using chemotherapy regimens that have incorporated Blinatumomab in the consolidation phase of treatment. …”
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Flavonoid-Deficient Mutants in Grass Pea (Lathyrus sativus L.): Genetic Control, Linkage Relationships, and Mapping with Aconitase and S-Nitrosoglutathione Reductase Isozyme Loci by Dibyendu Talukdar

“…Linkage studies and primary trisomic analysis mapped Aco 1 and fld 1 loci on extra chromosome of trisomic-I and Aco 2, fld 2, and Gsnor 2 on extra chromosome of trisomic-IV in linked associations.…”
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Flow Cytometric DNA Index and Karyotype in Childhood Lymphoblastic Leukemia by Erik Forestier, Gösta Holmgren, Göran Roos

“…A statistically significant correlation existed between modal chromosome number and DIFCM (p = 0.009). DIFCM could reliably identify leukemias with >51 chromosomes, whereas only three out of 12 cases with modal chromosome numbers between 47–51 were classified as aneuploid by DIFCM. …”
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Assembly of the salt-secreting mangrove Avicennia rumphiana. by Jeremy R Shearman, Chaiwat Naktang, Chutima Sonthirod, Wasitthee Kongkachana, Sonicha U-Thoomporn, Nukoon Jomchai, Chatree Maknual, Suchart Yamprasai, Poonsri Wanthongchai, Wirulda Pootakham, Sithichoke Tangphatsornruang

“…Reference based scaffolding produced 32 chromosome-level scaffolds containing 447.3 Mb, with 52.3 Mb of sequence unplaced. …”
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Child with Deletion 9p Syndrome Presenting with Craniofacial Dysmorphism, Developmental Delay, and Multiple Congenital Malformations by Nirmala D. Sirisena, U. Kalpani S. Wijetunge, Ramya de Silva, Vajira H. W. Dissanayake

“…Cytogenetic studies confirmed terminal deletion of the short arm of chromosome 9 distal to band p22 [46,XY,del(9)(p22→pter)]. …”
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Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei by Marija Krasiļņikova, Catarina A. Marques, Emma M. Briggs, Craig Lapsley, Graham Hamilton, Dario Beraldi, Kathryn Crouch, Richard McCulloch

“…Eleven megabase-sized chromosomes each comprise a transcribed core flanked by silent subtelomeres, housing thousands of Variant Surface Glycoprotein (VSG) genes. …”
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Analysis of significantly associated regions and candidate genes for dwarf stem trait in Brassica napus based on BSA-sequencing by ZHAO Weiguo, TA Na, WANG Hao, YANG Zelin

“…One significantly associated region was identified in the region from 21.78-23.88 Mb on chromosome A06. Five candidate genes within the significantly associated regions were identified and involved in the regulation of plant auxin synthesis and gibberellin signal transduction.…”
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USING <i> AVENA MACROSTACHYA </i> FOR IMPROVEMENT OF OAT WINTERHARDINESS IN POLAND by B. . Lapinski, A. . Rachwalska

“…The B1F or F2 generation consisted of plants with chromosome numbers between 40 and 49, octoploids (2n=56) and plants carrying 60 to 70 chromosomes. …”
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Cryoimmobilized anther analysis reveals new ultrastructural insights into Rhynchospora (Cyperaceae) asymmetrical microsporogenesis by Danilo M. Rocha, Ulla Neumann, Fernanda M. Nogueira, Georgios Tsipas, André L. L. Vanzela, André Marques

“…IntroductionThe Cyperaceae family is distinguished by holocentric chromosomes and a distinctive microsporogenesis process, which includes inverted meiosis, asymmetric tetrad formation, selective cell death, and the formation of pseudomonad pollen. …”
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Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome by Asma Deeb

“…Wolf-Hirschhorn Syndrome (WHS) is a rare genetic disease caused by deletion in the short arm of chromosome 4. It is characterized by typical fascial features and a varying degree of intellectual disabilities and multiple systemic involvement. …”
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DiGeorge Syndrome Presenting as Hypocalcaemia-Induced Seizures in Adulthood by Adrian Zammit, Deborah Grech Marguerat, Josephine Psaila, Alexander Attard

“…DiGeorge syndrome is a developmental defect commonly caused by a microdeletion on the long arm of chromosome 22 or less frequently by a deletion of the short arm of chromosome 10. …”
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Extra Copies of der(21)t(12;21) plus Deletion of ETV6 Gene due to dic(12;18) in B-Cell Precursor ALL with Poor Outcome by Marina Araújo Fonzar Hernandes, Terezinha de Jesus Marques-Salles, Hasmik Mkrtchyan, Eliane Maria Soares-Ventura, Edinalva Pereira Leite, Maria Tereza Cartaxo Muniz, Maria Teresa Marquim Nogueira Cornélio, Thomas Liehr, Neide Santos, Maria Luiza Macedo Silva

“…Some relapse cases and unfavorable prognosis in ALL CD10+ are associated with t(12;21) bearing additional aberrations as extra copies of chromosome 21 and ETV6 gene loss. This report describes the case of a 15 month-year old girl, who displayed a karyotype with addition on chromosome 12p plus trisomy 10 and tetrasomy of chromosome 21. …”
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A genome-wide association study identifies genetic variants associated with hip pain in the UK Biobank cohort (N = 221,127) by Qi Pan, Yiwen Tao, Tengda Cai, Abi Veluchamy, Harry L. Hebert, Peixi Zhu, Mainul Haque, Tania Dottorini, Lesley A. Colvin, Blair H. Smith, Weihua Meng

“…Sex-stratified GWAS analyses revealed a unique locus within the CUL1 gene (rs4726995, p = 2.56 × 10–9) in males, and three unique loci in females: rs1651359966 on chromosome 7 (p = 1.15 × 10–8), rs552965738 on chromosome 9 (p = 2.72 × 10–8), and rs1978969 on chromosome 13 (p = 2.87 × 10–9). …”
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Movements of the Glandirana Frogs in Japan and South Korea: A Strategy for Defining Geographical Movements of Amphibians by Akira Oike, Koji Tojo, Yoriko Nakamura, Etsuro Ito, Masahisa Nakamura

“…To address the issue, we selected Glandirana rugosa as a representative of Japanese amphibians because this frog is the only species among amphibians in which nucleotide sequences of the mitochondrial genes and sex chromosome evolution have been deeply investigated. …”
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The role of HEPCAM in Jacobsen syndrome: A pediatric case report highlighting white matter abnormalities by Ghazaleh Ghorbannezhad, Reza Nejad Shahrokh Abadi, Farrokh Seilanian Toosi, Shima Shekari, Saeedeh Sadat Mirtooni, Narges Hashemi

“…Furthermore, deletion mutations in the long arm of chromosome 11 can also give rise to Megalocephalic Leukoencephalopathy (MLC), affecting the HEPCAM gene. …”
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Genetic parameters and parental and early-life effects of boar semen traits by Pedro Sá, Rodrigo M. Godinho, Marta Gòdia, Claudia A. Sevillano, Barbara Harlizius, Ole Madsen, Henk Bovenhuis

“…Mitochondrial DNA and Y chromosome inheritances showed no effect on semen traits. …”
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Assessment of diversity of Indian aromatic rice germplasm collections for morphological, agronomical, quality traits and molecular characters to identify a core set for crop improv... by G. S. V. Prasad, G. Padmavathi, K. Suneetha, M. S. Madhav, K. Muralidharan

“…The markers are informative in analyzing the diversity as the PIC values estimated varied from 0.17 (RM577 on chromosome 1) to 0.72 (RM276 on chromosome 6) with an average of 0.54 per locus. …”
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Contribution of Cytogenetics to the Debate on the Paraphyly of Pachycondyla spp. (Hymenoptera, Formicidae, Ponerinae) by Cléa dos Santos Ferreira Mariano, Silvia das Graças Pompolo, Janisete Gomes Silva, Jacques Hubert Charles Delabie

“…It is likely that karyotypes with a large number of chromosomes and comprising mostly small acrocentric chromosomes in species within the Pachycondyla stricto sensu group resulted from a succession of centric fission events. …”
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IDENTIFICATION OF A (1B)1R SUBSTITUTION AND 1BL.1RS TRANSLOCATION IN WINTER WHEAT INTROGRESSION LINES BY CYTOGENETIC AND MOLECULAR METHODS by I. I. Motsnyy, S. V. Chebotar, L. V. Sudarchuk, A. V. Galaev, Yu. M. Sivolap

“…The pairing between short arms of chromosomes 1BL.1RS and bread wheat chromosome 1B is observed at a very low frequency (in 0,2–0,3 % of pollen mother cells). …”
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The first insight into Acanthocephalus (Palaeacanthocephala) satellitome: species-specific satellites as potential cytogenetic markers by Anna Marková, Martina Orosová, Pablo Mora, Michal Benovics, Pedro Lorite

“…These newly identified satellites proved to be useful chromosomal markers for the accurate identification of homologous chromosome pairs. …”
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