Showing 9,961 - 9,980 results of 10,151 for search '"chemistry"', query time: 0.13s Refine Results
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  2. 9962

    Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

    Published 2025-03-01
    “…The AAV8-microdystrophin-FLAG led to ∼20% of wild-type NHP dystrophin protein expression levels and was located on the sarcolemma of ∼40% of skeletal muscles fibers and ∼15% of left ventricular cardiomyocytes. Hematology, serum chemistry, and pathology were unremarkable. Thus, a systemic dose of ∼1.18 × 1014 vector genomes/kg AAV8 is predicted to be safe and efficacious for treating Duchenne muscular dystrophy (DMD) but has significant room for improvement.…”
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    Current Status and Future Prospects of the SNO+ Experiment by S. Andringa, E. Arushanova, S. Asahi, M. Askins, D. J. Auty, A. R. Back, Z. Barnard, N. Barros, E. W. Beier, A. Bialek, S. D. Biller, E. Blucher, R. Bonventre, D. Braid, E. Caden, E. Callaghan, J. Caravaca, J. Carvalho, L. Cavalli, D. Chauhan, M. Chen, O. Chkvorets, K. Clark, B. Cleveland, I. T. Coulter, D. Cressy, X. Dai, C. Darrach, B. Davis-Purcell, R. Deen, M. M. Depatie, F. Descamps, F. Di Lodovico, N. Duhaime, F. Duncan, J. Dunger, E. Falk, N. Fatemighomi, R. Ford, P. Gorel, C. Grant, S. Grullon, E. Guillian, A. L. Hallin, D. Hallman, S. Hans, J. Hartnell, P. Harvey, M. Hedayatipour, W. J. Heintzelman, R. L. Helmer, B. Hreljac, J. Hu, T. Iida, C. M. Jackson, N. A. Jelley, C. Jillings, C. Jones, P. G. Jones, K. Kamdin, T. Kaptanoglu, J. Kaspar, P. Keener, P. Khaghani, L. Kippenbrock, J. R. Klein, R. Knapik, J. N. Kofron, L. L. Kormos, S. Korte, C. Kraus, C. B. Krauss, K. Labe, I. Lam, C. Lan, B. J. Land, S. Langrock, A. LaTorre, I. Lawson, G. M. Lefeuvre, E. J. Leming, J. Lidgard, X. Liu, Y. Liu, V. Lozza, S. Maguire, A. Maio, K. Majumdar, S. Manecki, J. Maneira, E. Marzec, A. Mastbaum, N. McCauley, A. B. McDonald, J. E. McMillan, P. Mekarski, C. Miller, Y. Mohan, E. Mony, M. J. Mottram, V. Novikov, H. M. O’Keeffe, E. O’Sullivan, G. D. Orebi Gann, M. J. Parnell, S. J. M. Peeters, T. Pershing, Z. Petriw, G. Prior, J. C. Prouty, S. Quirk, A. Reichold, A. Robertson, J. Rose, R. Rosero, P. M. Rost, J. Rumleskie, M. A. Schumaker, M. H. Schwendener, D. Scislowski, J. Secrest, M. Seddighin, L. Segui, S. Seibert, T. Shantz, T. M. Shokair, L. Sibley, J. R. Sinclair, K. Singh, P. Skensved, A. Sörensen, T. Sonley, R. Stainforth, M. Strait, M. I. Stringer, R. Svoboda, J. Tatar, L. Tian, N. Tolich, J. Tseng, H. W. C. Tseung, R. Van Berg, E. Vázquez-Jáuregui, C. Virtue, B. von Krosigk, J. M. G. Walker, M. Walker, O. Wasalski, J. Waterfield, R. F. White, J. R. Wilson, T. J. Winchester, A. Wright, M. Yeh, T. Zhao, K. Zuber

    Published 2016-01-01
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    Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells by Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J

    Published 2025-02-01
    “…Chao Cheng,1,* Minjia Sun,1– 3,* Jingjing Li,1,* Yitong Xue,1 Xia Cai,4 Jing Liu,1 Xiaolian Wang,5 Shouhong Xu,2 Youhua Xie,1 Junqi Zhang1 1MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, People’s Republic of China; 2Key Laboratory for Advanced Materials and Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, People’s Republic of China; 3Zhejiang CONBA Pharmaceutical Co., Ltd, Hangzhou, 310052, People’s Republic of China; 4Shanghai Medical College, Biosafety Level 3 Laboratory, Fudan University, Shanghai, 200032, People’s Republic of China; 5Department of Pathogeny Microbiology and Preventive Medicine, School of Medicine, Hexi University, Zhangye, 734000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junqi Zhang, Email junqizhang@fudan.edu.cn; Youhua Xie, Email yhxie@fudan.edu.cnPurpose: Human noroviruses (HuNoVs) are the main cause of non-bacterial acute gastroenteritis. …”
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