The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation by Ekta Bajwa, Caitlin B. Pointer, Andis Klegeris

“…In this review, we highlight the mitochondrial DAMPs cytochrome c (CytC), mitochondrial transcription factor A (TFAM), and cardiolipin and explore their potential role in the central nervous system disorders including Alzheimer’s disease and Parkinson’s disease, which are characterized by neurodegeneration and chronic neuroinflammation.…”
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Sedation and Analgesia in Children with Developmental Disabilities and Neurologic Disorders by Todd J. Kilbaugh, Stuart H. Friess, Ramesh Raghupathi, Jimmy W. Huh

“…The overall objectives of this paper are (1) to provide an overview on recent studies that highlight the increased risk for respiratory complications following sedation and analgesia in children with developmental disabilities and neurologic disorders, (2) to provide a better understanding of sedatives and analgesic medications which are commonly used in children with developmental disabilities and neurologic disorders on the central nervous system.…”
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Chronic pain in a family doctor practice – meaning, assessment, and therapeutic options by Dominika Prokop, Mikołaj Borek, Jan Baran, Dawid Rowiński, Oliwia Sikora, Katarzyna Chamera-Cyrek, Aneta Podczerwińska, Clara Kuzminski

“…Appropriately tailored therapeutic management is crucial because insufficient pain relief negatively affects the central nervous system, potentially leading to behavioural changes, emotional and psychological disorders, cognitive dysfunctions, abnormalities in cerebral blood flow, and a decrease in the number of neurons.…”
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Nail-Patella Syndrome Associated with Short Stature: A Case Series by Samir Haddad, Leila Ghedira-Besbes, Chahra Bouafsoun, Sabeur Hammami, Slaheddine Chouchene, Chebil Ben Meriem, Mohamed-néji Guediche

“…Nail-patella syndrome (NPS) is a rare genetic disorder that is characterized by a pleiotropic malformation affecting the nail, the skeleton, and occasionally the central nervous system and the kidneys. Case Presentation. …”
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Long-Term Remission of a Spinal Atypical Teratoid Rhabdoid Tumor in Response to Intensive Multimodal Therapy by Fahd Refai, Haneen Al-Maghrabi, Hassan Al Trabolsi, Jaudah Al-Maghrabi

“…Atypical teratoid rhabdoid tumors (ATRTs) are rare and aggressive central nervous system tumors that infrequently arise in spinal locations in young children. …”
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Glycosaminoglycan Storage Disorders: A Review by Maria Francisca Coutinho, Lúcia Lacerda, Sandra Alves

“…Typical symptoms include organomegaly, dysostosis multiplex, and coarse facies. Central nervous system, hearing, vision, and cardiovascular function may also be affected. …”
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Melphalan Culprit or Confounder in Acute Encephalopathy during Autologous Hematopoietic Stem Cell Transplantation? by Diógenes Alayón-Laguer, Melissa Alsina, Jose L. Ochoa-Bayona, Ernesto Ayala

“…The most common etiologies for encephalopathy such as infection, narcotic medications, metabolic-electrolyte disturbance, stroke, and central nervous system (CNS) hemorrhages were ruled out. The patient recovered from the altered mental status spontaneously. …”
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Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor by Daniel D. Kim, Ghassan Ghorayeb

“…The pathogenesis is controversial but is associated with a recent viral illness and can involve the central nervous system with concern for cerebral vasculitis. …”
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Successful Treatment of Multiple Multidrug Resistant Intracranial Tuberculomata by Richard P. Sullivan, Hazel F. Goldberg, Ross S. Mellick, Jeffrey J. Post

“…Management is complex and requires consideration of the penetration and likely effect of antituberculous agents within the central nervous system. We discuss the role of various antituberculous agents, the duration of therapy, the utility of corticosteroids, the value of intrathecal and systemic therapy, and the need for rapid diagnosis.…”
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Treatment of neuro-invasive listeriosis: an overview by P. Gudeikaitė, J. Valaikienė, R. Mameniškienė

“…Listeria monocytogenes is an aerobic gram-positive bacillus that can cause invasive listeriosis in humans, which most commonly affects the central nervous system. Clinically, neurolisteriosis occurs as meningoencephalitis, which is associated with the highest mortality rate in patients with severe conditions. …”
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Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression by Amanda Gollo Bertollo, Camila Ferreira Santos, Margarete Dulce Bagatini, Zuleide Maria Ignácio

“…In parallel, the gut-brain axis, a bidirectional communication network between the gut microbiota and the central nervous system, influences emotional and cognitive functions. …”
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Innovative IOP-Independent Neuroprotection and Neuroregeneration Strategies in the Pipeline for Glaucoma by James C. Tsai

“…Alongside this new knowledge, enhanced opportunities for discovery of vision preservation and/or restoration therapies must be weighed against the potential disadvantages of perturbing the complex central nervous system environment.…”
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Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke by Grace Hey, Ilyas Mehkri, Yusuf Mehkri, Hasan Maqbool, Mubariz Tahirkheli, Samuel Woodford, Brandon Lucke-Wold

“…Neurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpredictable. …”
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Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized tria... by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

“…Abstract Background Glioma is a brain tumor and glioblastoma represents its most common type, accounting for almost 40% of primary tumors of the central nervous system, and is associated with the worst prognosis. …”
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Clinical features of early multiple sclerosis by I. Čelpačenko, R. Stankevičiūtė, M. Malciūtė, R. Balnytė

“…A retrospective analysis of data was performed in patients hospitalized with the following ICD-10 (International Classification of Diseases Version 10) diagnoses: G37.8 (other specified demyelinating diseases of central nervous system) and G37.9 (demyelinating disease of central nervous system, unspecified). …”
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Sweet Taste Receptor Signaling Network: Possible Implication for Cognitive Functioning by Menizibeya O. Welcome, Nikos E. Mastorakis, Vladimir A. Pereverzev

“…Based on increasing evidence about the role of these receptors in the initiation and control of absorption and metabolism, and the pivotal role of metabolic (glucose) regulation in the central nervous system functioning, we propose a possible implication of sweet taste receptor signaling in modulating cognitive functioning.…”
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Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder? by Jay P. Patel, Benicio N. Frey

“…The blood-brain barrier (BBB) regulates the transport of micro- and macromolecules between the peripheral blood and the central nervous system (CNS) in order to maintain optimal levels of essential nutrients and neurotransmitters in the brain. …”
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Gender Differences in Behçet’s Disease Associated Uveitis by Didar Ucar-Comlekoglu, Austin Fox, H. Nida Sen

“…Behçet’s disease is a systemic vasculitis of unknown etiology, characterized by oral and genital ulceration, skin lesions, and uveitis as well as vascular, central nervous system, and gastrointestinal system involvement. …”
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Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease by Lenka Hromadkova, Saak Victor Ovsepian

“…Based on the emerging evidence, we cautiously propose that impairments of tau clearance at the periphery by humoral immunity might aggravate the tau pathology in the central nervous system, with implication for the neurodegenerative process of AD.…”
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Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain by Jason R. Andrews, Yoon Andrew Cho-Park, Judith Ferry, Jeremy S. Abramson, Gregory K. Robbins

“…We report an unusual case of KSHV-associated lymphoma in an HIV-infected patient manifesting with myocardial and central nervous system involvement. We discuss this case in the context of increasing array of KSHV-associated lymphomas. …”
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