-
121
Lysyl oxidase inhibitors in colorectal cancer progression
Published 2025-02-01“…Numerous studies have demonstrated that LOX family members are dysregulated in a variety of cancers, including colorectal cancer (CRC), and play a key role in cancer cell migration, proliferation, invasion and metastasis. …”
Get full text
Article -
122
IL-1 Receptor Antagonist Protects the Osteogenesis Capability of Gingival-Derived Stem/Progenitor Cells under Inflammatory Microenvironment Induced by Porphyromonas gingivalis Lipo...
Published 2021-01-01“…Cell behaviors including proliferation, cloning formation unit (CFU), cell migration, osteogenic differentiation, mineral deposition, and cytokine production were assessed to investigate the protection effect of IL-1ra on GMSCs under inflammation. …”
Get full text
Article -
123
More than the barrier effect: Biodegradable Mg-Ag alloy membranes for guided bone/tissue regeneration
Published 2024-11-01“…Mg-Ag alloys with different Ag contents were engineered to facilitate the cell migration of murine fibroblasts (L929) and the osteogenic differentiation of rat bone mesenchymal stem cells (rBMSCs). …”
Get full text
Article -
124
Epithelial–Mesenchymal Transition Suppression by ML210 Enhances Gemcitabine Anti-Tumor Effects on PDAC Cells
Published 2025-01-01“…Specifically, low dose ML210 in combination with GEM was sufficient for cell migration without apparent toxicity or cell death. …”
Get full text
Article -
125
Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment
Published 2025-01-01“…SMC4 inhibition reduced LN299 cell migration and increased chemotherapy sensitivity, decreasing CD4 and CD8 T cell activation.ConclusionsDisulfidptosis-Tex genes are pivotal in glioblastoma progression and immune interactions, offering new avenues for improving anti-glioblastoma therapies through modulation of T cell exhaustion.…”
Get full text
Article -
126
Cellular MR Imaging
Published 2005-07-01“…It appears that this issue has now largely been resolved, leading to an active research on monitoring the cellular biodistribution in vivo following transplantation or transfusion of these cells, including cell migration and trafficking. New applications of cellular MR imaging will be directed, for instance, towards our understanding of hematopoietic (immune) cell trafficking and of novel guided (stem) cell-based therapies aimed to be translated to the clinic in the future.…”
Get full text
Article -
127
Anti-tumor role and molecular mechanism of vanillic acid
Published 2025-01-01“…Furthermore, VA disrupts the cancer cell cycle, arresting most cancer cells at the G1 phase, curtails cell migration, invasion, angiogenesis, and potentiates the therapeutic efficacy of chemotherapeutic drugs, all while minimizing adverse reactions. …”
Get full text
Article -
128
Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor
Published 2011-01-01“…The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal transitions (EMTs). …”
Get full text
Article -
129
17β-estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells.
Published 2018-01-01“…In conclusion, our results demonstrated that E2-mediated upregulation of striatin promotes cell migration in HUVECs.…”
Get full text
Article -
130
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Conclusions Our findings unveil DAPK1-215 as a molecular brake on DAPK1 expression, influencing cancer cell migration and invasion in a context-dependent manner. …”
Get full text
Article -
131
The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer
Published 2016-01-01“…In addition, interaction of HA and CD44 promotes EGFR-mediated pathways, consequently leading to tumor cell growth, tumor cell migration, and chemotherapy resistance in solid cancers. …”
Get full text
Article -
132
Regulators of Actin Dynamics in Gastrointestinal Tract Tumors
Published 2015-01-01“…Reorganization of the actin cytoskeleton underlies cell migration in a wide variety of physiological and pathological processes, such as embryonic development, wound healing, and tumor cell invasion. …”
Get full text
Article -
133
Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture
Published 2013-01-01“…Lovastatin strongly inhibited cell migration from aortic explants and caused the degradation of the capillary tubes. …”
Get full text
Article -
134
Cardiovascular Effects Mediated by HMMR and CD44
Published 2021-01-01“…Both RHAMM and CD44 are involved in cell migration and wound healing. However, their close association with CVD is not fully understood. …”
Get full text
Article -
135
Sugar Antennae for Guidance Signals: Syndecans and Glypicans Integrate Directional Cues for Navigating Neurons
Published 2006-01-01“…Recently, heparan sulfate proteoglycans (HSPGs), which are present on the cell surface of neurons and in the extracellular matrix through which neurons and axons migrate, have been found to play a role in regulating cell migration and axon guidance. Intriguingly, the large number of distinct modifications that can be put onto the sugar side chains of these PGs would in principle allow for an enormous diversity of HSPGs, which could help in regulating the vast number of guidance choices taken by individual neurons. …”
Get full text
Article -
136
Vertex model with internal dissipation enables sustained flows
Published 2025-01-01“…Our findings also show a simple mechanism that could account for collective cell migration correlated over distances large compared to the cell size, as observed during morphogenesis.…”
Get full text
Article -
137
The Oxidative State of Chylomicron Remnants Influences Their Modulation of Human Monocyte Activation
Published 2012-01-01“…Chylomicron remnants (CMRs) contribute directly to human monocyte activation in vitro, by increasing reactive oxygen species (ROS) production and cell migration. In this study, the effects of the oxidative state of CMR on the degree of monocyte activation was investigated. …”
Get full text
Article -
138
Mesenchymal Stem Cells and their Derived Exosomes Promote Malignant Phenotype of Polyploid Non-Small-Cell Lung Cancer Cells through AMPK Signaling Pathway
Published 2022-01-01“…Compared with the control group, MSCs and MSC-exosomes significantly promoted epithelial mesenchymal transformation, cell migration, antiapoptosis, and autophagy in the polyploid A549 and H1299 by activating AMPK signaling pathway, but no significant changes were observed in MSC-CM treatment. …”
Get full text
Article -
139
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo
Published 2025-01-01“…Data furthermore indicate that the exosomes released through this NRP1-driven mechanism effectively transfer miR-210-3p to human endothelial cells, causing paracrine downregulation of the regulatory cue ephrin-A3 and promotion of cell migration. The mechanistic involvement of miR-210-3p in this pathway was confirmed by applying a specific antago-miR. …”
Get full text
Article -
140
Collagen prolyl 4-hydroxylase subunit α member-induced head and neck squamous cell carcinoma aggressiveness is antagonized by LLGL2 via redu...
Published 2024-10-01“…In contrast, knocking down C-P4HA alone inhibits cell migration and invasion. Furthermore, simultaneously downregulating three C-P4HAs has more pronounced effects on inhibiting cell migration and invasion. …”
Get full text
Article