Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study by Yanbiao Liao, Chang Liu, Tianyuan Xiong, Mingyue Zhao, Wen Zheng, Yuan Feng, Yijian Li, Yuanweixiang Ou, Zhengang Zhao, Yong Peng, Jiafu Wei, Qiao Li, Wei Meng, Xiaojing Liu, Mao Chen

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HeartMate 3 upgrade and aortic root replacement for severe aortic insufficiency and ventricular fibrillation by Katlin T. Schmitz, MD, Sara S. Inglis, MB, BCh, BAO, Mauricio A. Villavicencio, MD, MBA, Adrian daSilva-deAbreu, MD, MSc, PhD(c)

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A Systematic Review and Meta-Analysis of Risk Factors Associated with Severity and Death in COVID-19 Patients by Pengqiang Du, Dandan Li, Aifeng Wang, Su Shen, Zhichao Ma, Xingang Li

“…Advanced age (≥65 years, severe illness, OR = 2.62; death, OR = 6.00), male (severe illness, OR = 1.49; death, OR = 1.54), chronic respiratory diseases (severe illness, OR = 5.67; death, OR = 3.72), diabetes (severe illness, OR = 3.27; death, OR = 2.60), hypertension (severe illness, OR = 3.08; death, OR = 3.53), chronic kidney disease (severe illness, OR = 3.59; death, OR = 5.38), and cardiovascular diseases (severe illness, OR = 3.87; death, OR = 4.91) were all risk factors. …”
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Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology by Yin-Feng Zhang, Hai-Ming Xu, Fei Yu, Man Wang, Meng-Yang Li, Tao Xu, Yan-Yan Gao, Jian-Xun Wang, Pei-Feng Li

“…These vital roles make PPARs potential targets for therapeutic prevention of cardiovascular diseases (CVDs). Emerging evidence indicates that the crosstalk of microRNAs (miRNAs) and PPARs contributes greatly to CVD pathogenesis. …”
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Ventricular-arterial coupling: changes with ageing and implications across cardiovascular conditions by Mateusz Gaczoł, Marek Rajzer, Wiktoria Wojciechowska

“…This comprehensive literature review explores the changes in VAC with ageing and various cardiovascular diseases (CVDs).Materials and methods This literature review covers studies on changes in VAC with age and common CVDs, such as arterial hypertension, atrial fibrillation (AF) and heart failure with preserved and reduced ejection fraction and aortic stenosis (AS). …”
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Cardiovascular Risk Factors and Distributions of the Ankle-Brachial Index among Type 2 Diabetes Mellitus Patients by Badaruddoza Doza, Manpreet Kaur, Sonia Chopra, Rohit Kapoor

“…History of symptoms related to cardiovascular diseases was noted, and blood pressure and anthropometric measurements were recorded. …”
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Association between composite dietary antioxidant index and hyperlipidemia in adults based on the NHANES by Kaidi Nie, Tingting Deng, Yiling Bai, Yuxian Zhang, Zhixuan Chen, Xile Peng, Lina Xia, Jiao Liu

“…Abstract Hyperlipidemia, a major risk factor for cardiovascular diseases, can potentially be alleviated by dietary antioxidants. …”
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Fat from Tenebrionidae Bugs - Sterols Content, Fatty Acid Profiles, and Cardiovascular Risk Indexes by Jiri Mlcek, Anna Adamkova, Martin Adamek, Marie Borkovcova, Martina Bednarova, Ivana Knizkova

“…These indexes are often considered predictors of cardiovascular diseases. A potential benefit of both species could be the balanced proportion of sterols of animal and plant origin that could be nutritionally well-accessible and lower weight of dry matter necessary to consume to cover the daily dose of linoleic acid compared to dried beef.…”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…This disorder affects approximately 6–20% of individuals, primarily emerging during early adolescence, and considerably increases the risk of conditions such as impaired glucose tolerance, type 2 diabetes, endometrial cancer, cardiovascular diseases, dyslipidemia, and postpartum complications. …”
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Time-variant left ventricle models for intracardiac impedance analysis by Voss Daniel, Wemmer Clara, Leonhardt Steffen, Walter Marian

“…Cardiovascular diseases are a leading cause of mortality worldwide. …”
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The Optimal Intervention Time of Bone Marrow Mesenchymal Stem Cells in Ameliorating Cardiac Fibrosis Induced by Viral Myocarditis: A Randomized Controlled Trial in Mice by Tingting Wu, Yuan Xie, Jing Huang, Ping Li, Xuliang Wang, Yaoyao Yan, Tianhe Xia, Lei Li, Feng Zhu, Hao Li, Rongzhou Wu

“…Bone marrow-derived mesenchymal stem cells (BMSCs) have recently been introduced to treat cardiovascular diseases, such as myocardial infarction and dilated cardiomyopathy. …”
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Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes by Antonio Junior Lepedda, Gabriele Nieddu, Silvia Rocchiccioli, Nadia Ucciferri, Michela Idini, Pierina De Muro, Marilena Formato

“…Diabetes mellitus is a global health problem representing the fifth leading cause of mortality and a major risk factor for cardiovascular diseases. In the last years, we reported an association among urinary trypsin inhibitor (UTI), a small proteoglycan that plays pleiotropic roles in many inflammatory processes, and both type 1 and 2 diabetes and developed a method for its direct quantitation and structural characterization. …”
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Leptin Modifies the Rat Heart Performance Associated with Mitochondrial Dysfunction Independently of Its Prohypertrophic Effects by Edna Berzabá-Evoli, Cecilia Zazueta, Jarumi Hishel Cruz Hernández, Nancy Patricia Gómez-Crisóstomo, Isela Esther Juárez-Rojop, Erick Natividad De la Cruz-Hernández, Eduardo Martínez-Abundis

“…Therefore, leptin could be a link between obesity and the prevalence of cardiovascular diseases. On the other hand, a deleterious effect of leptin on mitochondrial performance was described, which was also associated with the evolution of cardiac hypertrophy to heart failure. …”
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Development of a Novel Sensor System Based on Magnetic Microspheres to Detect Cardiac Troponin T by Junrong Zhang, Hongxiang Liu, Baofeng Xu, Sijun Huang, Rui Liu, Jinming Zhu, Yi Guo, Li Xu

“…The present study is aimed at exploring a novel sensing system with high specificity and precision based on magnetic microspheres developed to detect cardiac troponin T (cTnT), which is the most specific diagnostic marker for AMI in cardiovascular diseases. Naive human cTnT protein in serum samples and antigens on functional magnetic microspheres will competitively bind with limited specific antibodies. …”
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Medicines for the management of overweight and obesity: A systematic review with network meta-analysis by Gabriela Masiero Marcon, Jhonatan Mendes Paiva, Mariana Delariva Sakiyama, Fernanda Stumpf Tonin, Fernando Fernandez-Llimos, Suzane Virtuoso, Andreia Cristina Conegero Sanches

“…Besides that, we suggest re-evaluating of sibutramine 10mg/day as a therapeutic option for patients without hypertension or cardiovascular diseases, and we demonstrate the modest weight loss promoted by orlistat 120mg, sibutramine 5mg, and liraglutide 1,8mg and advise against its use, once the benefits do not outweigh the risks.…”
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Sulfated and Phosphorylated Agarose as Biomaterials for a Biomimetic Paradigm for FGF-2 Release by Aurelien Forget, V. Prasad Shastri

“…Cardiovascular diseases such as myocardial infarction or limb ischemia are characterized by regression of blood vessels. …”
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PPARγ and Its Agonists in Chronic Kidney Disease by Yuhua Ma, Manman Shi, Yuxin Wang, Jian Liu

“…The major risk factors for CKD include obesity, diabetes, and cardiovascular diseases. Understanding the key process involved in the disease development may lead to novel interventive strategies, which is currently lagging behind. …”
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Visfatin/Nampt: An Adipokine with Cardiovascular Impact by Tania Romacho, Carlos F. Sánchez-Ferrer, Concepción Peiró

“…Moreover, visfatin/Nampt circulating levels correlate with markers of systemic inflammation. In cardiovascular diseases, visfatin/Nampt was initially proposed as a clinical marker of atherosclerosis, endothelial dysfunction, and vascular damage, with a potential prognostic value. …”
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Characterization of the Scientific Output of Health Professionals from Cienfuegos Visible in the Scopus Database by Yuniet Rojas Mesa, María Elinor Dulzaides Iglesias, Ana María Molina Gómez, Carlos Caballero Díaz

“…Most common topics are: cardiovascular diseases and public health. Collaboration with 13 institutions (nine papers with four national institutes and 30 with foreign institutions) was observed. …”
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Vitamin D Deficiency Contributes to the Reduction and Impaired Function of Naïve CD45RA+ Regulatory T Cell in Chronic Heart Failure by Yan-hui Ma, Yun-lan Zhou, Chao-yan Yue, Guang-hui Zhang, Lin Deng, Guo-hua Xie, Wei-ping Xu, Li-song Shen

“…In this study, we demonstrated that plasma 25(OH)D level, negatively associated with NT-ProBNP, correlated with the decreased Treg in CHF compared to the patients with other cardiovascular diseases and healthy and older donors. Naïve Treg cell (CD4+CD45RA+Foxp3loT) subset, rather than whole Treg cells, contributes to the reduction of Treg in CHF. 1,25(OH)2D treatment maintained partial expression of CD45RA on CD4+T cell after αCD3/CD28 monoclonal antibodies activation and ameliorated the impaired CD4+CD45RA+T cell function from CHF patients through upregulating Foxp3 expression and IL-10 secretion in vitro. …”
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