Dexamethasone Prophylaxis in Pediatric Open Heart Surgery Is Associated with Increased Blood Long Pentraxin PTX3: Potential Clinical Implications by Franco Lerzo, Giuseppe Peri, Andrea Doni, Paola Bocca, Fabio Morandi, Angela Pistorio, Anna Maria Carleo, Alberto Mantovani, Vito Pistoia, Ignazia Prigione

“…Dexamethasone prophylaxis in pediatric patients undergoing CPB for cardiac surgery is associated with a significant increase of blood PTX3 that could contribute to decreasing inflammatory parameters and improving patient clinical outcome.…”
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Outcomes of Worsened Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Replacement by Hu Z, Wang C, Luo S, Yang B, Zheng S, Hu X, Sun Y, Chen J, Fu M, Fan R, Luo J, Li J

“…Ziyang Hu,1,* Changjin Wang,2,* Songyuan Luo,2,* Bangyuan Yang,2 Shengneng Zheng,3 Xiaolu Hu,2,4 Yinghao Sun,2 Jiaohua Chen,2 Ming Fu,2 Ruixin Fan,5 Jianfang Luo,2,4 Jie Li2 1Department of Cardiology, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 3Department of Radiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 4School of Medicine South China University of Technology, Guangzhou, People’s Republic of China; 5Department of Cardiac Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Li; Jianfang Luo, Guangdong Provincial People’s Hospital, #96 Dongchuan Road, Yuexiu District, Guangzhou, Guangdong, 510080, People’s Republic of China, Tel +86 020 83827812, Email leomoku1981@163.com; jianfangluo@sina.comBackground: Left ventricular ejection fraction (LVEF) worsening after transcatheter aortic valve replacement (TAVR) was common in clinical practice. …”
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Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation by Xiaoyu Yu, Weiwei Wu, Jingjun Hao, Yuxin Zhou, Deyang Yu, Wei Ding, Xuejuan Zhang, Gaoli Liu, Jianxun Wang

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Analysis of chronic kidney disease epidemiology in Kazakhstan using nationwide data for 2014–2020 and forecasting future trends of prevalence and mortality for 2030 by Gulnur Zhakhina, Kamilla Mussina, Sauran Yerdessov, Arnur Gusmanov, Yesbolat Sakko, Valdemir Kim, Dmitriy Syssoyev, Meruyert Madikenova, Ainur Assan, Zhanat Kuanshaliyeva, Duman Turebekov, Kuanysh Yergaliyev, Bolat Bekishev, Abduzhappar Gaipov

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Frailty assessment tools for use by surgeons when evaluating older adults prior to surgery: a scoping review protocol by Duminda N Wijeysundera, Andrea C Tricco, Martine T E Puts, Shabbir M H Alibhai, Teruko Kishibe, Tyler R Chesney, Julian F Daza, Camilla Wong, Karim Shiraz Ladha, Samuel Dubé

“…We will include all studies evaluating a frailty assessment tool preoperatively in patients 65 years or older undergoing intracavitary, non-cardiac surgery. We will exclude tools not assessed in clinical practice, or using laboratory or radiologic values alone. …”
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Intraoperative haemodynamic optimisation using the Hypotension Prediction Index and its impact on tissular perfusion: a protocol for a randomised controlled trial by Javier Ripollés-Melchor, Ane Abad-motos, Juan Victor Lorente, Ignacio Jimenez, Alejandra Becerra, Wilbert Wesselink, Francesca Reguant, Irene Mojarro, Maria de los Angeles Fuentes, Elizabeth Agudelo, Francisco Herrero-Machancoses, Paula Callejo, Joan Bosch, Manuel Ignacio Monge

“…The use of this index may reduce the duration and severity of intraoperative hypotension in adults undergoing non-cardiac surgery. This study aims to determine whether a treatment protocol based on the prevention of arterial hypotension using the HPI algorithm reduces the duration and severity of intraoperative hypotension compared with the recommended goal-directed fluid therapy strategy and may improve tissue oxygenation and organ perfusion.Methods and analysis We will conduct a multicentre, randomised, controlled trial (N=80) in high-risk surgical patients scheduled for elective major abdominal surgery. …”
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Diagnostic Evaluation and Management of Chronic Thromboembolic Pulmonary Hypertension: A Clinical Practice Guideline by Sanjay Mehta, Doug Helmersen, Steeve Provencher, Naushad Hirani, Fraser D Rubens, Marc De Perrot, Mark Blostein, Kim Boutet, George Chandy, Carole Dennie, John Granton, Paul Hernandez, Andrew M Hirsch, Karen Laframboise, Robert D Levy, Dale Lien, Simon Martel, Gerard Shoemaker, John Swiston, Justin Weinkauf

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A bibliometric analysis of publications in 3D printing in surgery from the web of science database by Bitesh Kumar, Anjan Kumar Dhua, Mohit Garg, Vishesh Jain, Devendra Kumar Yadav, Prabudh Goel, Sachit Anand, Divya Jain

“…Background: Three-dimensional (3D) printing technology, introduced by Charles Hull in 1986, has revolutionized prototyping and is increasingly applied in medical fields such as orthopedics, neurosurgery, and cardiac surgery. The technology offers numerous benefits, including reduced surgical complications, cost-effectiveness, and customization of medical devices. …”
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European System for Cardiac Operative Risk Evaluation II and Liver Dysfunction by Andreea Ludusanu, Adelina Tanevski, Bogdan Mihnea Ciuntu, Razvan Lucian Bobeica, Dragos Andrei Chiran, Cristinel Ionel Stan, Viorel Dragos Radu, Vasile Lucian Boiculese, Grigore Tinica

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Cerebral Microhemorrhages in Children With Congenital Heart Disease: Prevalence, Risk Factors, and Association With Neurodevelopmental Outcomes by Kristen N. Andersen, Sicong Yao, Brian R. White, Marin Jacobwitz, Jake Breimann, Jharna Jahnavi, Alexander Schmidt, Wesley B. Baker, Tiffany S. Ko, J. William Gaynor, Arastoo Vossough, Rui Xiao, Daniel J. Licht, Evelyn K. Shih

“…Methods and Results One hundred ninety‐two infants with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass were evaluated with pre‐ (n=183) and/or postoperative (n=162) magnetic resonance imaging. …”
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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

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The Australian and New Zealand Fontan Registry Quality of Life Study: Protocol for a population-based assessment of quality of life among people with a Fontan circulation, their pa... by Daniel S J Costa, Kim Dalziel, Yves d’Udekem, David S Winlaw, David S Celermajer, Nadine A Kasparian, Diana Zannino, Rachel Bishop, Kate H Marshall, Susan R Woolfenden, Gary F Sholler

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The clinical utility of tissue polymerase chain reaction, tissue culture and tissue histology in blood culture-negative infective endocarditis in South Africa – insights from the G... by W Endres, P Mkoko, M Ntsekhe

“…Twenty-seven of the 57 BCNIE patients underwent cardiac surgery and had tissue analysis performed. Tissue PCR identified an aetiological agent in 17/27 (63%) cases, with Bartonella spp. (12/27, 44%) being the most common organism. …”
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Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

“…ObjectiveThe principal goal of the Innovation in Postoperative Rehabilitation Training and Monitoring (IPOTERI) study is to design, realize, and test a composite and integrated system for postsurgical rehabilitation therapies at home specialized for cardiac surgery. The secondary aims are to implement the system in a “real-life” context of postcardiac surgical rehabilitation, and to create a data set and a data collection methodology to prototype data analytics algorithms and artificial intelligence techniques for customizing the rehabilitation pathway. …”
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Log odds of positive lymph nodes compared to positive lymph node ratio and number of positive lymph nodes in prognostic modeling for patients with NSCLC undergoing lobectomy or tot... by Qiming Huang, Shai Chen, Zhenjie Li, Longren Wu, Dongliang Yu, Linmin Xiong

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Early sST2 Liberation after Implantation of a Left Ventricular Assist Device in Patients with Advanced Heart Failure by Philipp Opfermann, Elisabeth Simader, Alessia Felli, Michele Bevilacqua, Caroline Holaubek, Martin Dworschak, Mohamed Mouhieddine, Daniel Zimpfer, Jan Hendrik Ankersmit, Barbara Steinlechner

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A New Risk Prediction Model for the Assessment of Myocardial Injury in Elderly Patients Undergoing Non-Elective Surgery by Vedat Cicek, Mert Babaoglu, Faysal Saylik, Samet Yavuz, Ahmet Furkan Mazlum, Mahmut Salih Genc, Hatice Altinisik, Mustafa Oguz, Berke Cenktug Korucu, Mert Ilker Hayiroglu, Tufan Cinar, Ulas Bagci

“…<b>Aims:</b> This study aimed to create a new risk prediction model to assess myocardial injury after non-cardiac surgery (MINS) in elderly patients and compare it with the RCRI, a well-known pre-operative risk prediction model. …”
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Long-term cardiovascular outcomes after percutaneous coronary intervention in patients with systemic sclerosis by Kazutoshi Hirose, Hiroyuki Kiriyama, Shun Minatsuki, Yugo Nagae, Tatsuki Furusawa, Takashi Hiruma, Atsushi Kobayashi, Masataka Sato, Shinnosuke Sawano, Tatsuya Kamon, Hiroki Shinohara, Mizuki Miura, Akihito Saito, Satoshi Kodera, Junichi Ishida, Norifumi Takeda, Hiroyuki Morita, Issei Komuro, Norihiko Takeda

“…However, CAD tended to be more complex in the SSc group because of the higher proportion of left main trunk lesions (p = 0.100) and higher SYNergy between PCI with TAXUS™ and Cardiac Surgery (SYNTAX) score (p = 0.030). During a median follow-up of 3.1 years, patients with SSc more frequently experienced primary and secondary outcomes than those without SSc (both log-rank p < 0.02). …”
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Pluripotency-State-Dependent Role of Dax1 in Embryonic Stem Cells Self-Renewal by Jianrong He, Yuda Cheng, Yan Ruan, Jiali Wang, Yanping Tian, Jiaqi Wang, Fengsheng Wang, Chen Zhang, Yixiao Xu, Lianlian Liu, Meng Yu, Jiangjun Wang, Binyu Zhao, Yue Zhang, Yi Yang, Gaoke Liu, Wei Wu, Ping He, Jiaxiang Xiong, He Huang, Junlei Zhang, Rui Jian

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Outcomes of patients after successful left ventricular assist device explantation: a EUROMACS study by Christiaan F.J. Antonides, Felix Schoenrath, Theo M.M.H. deBy, Rahatullah Muslem, Kevin Veen, Yunus C. Yalcin, Ivan Netuka, Jan Gummert, Evgenij V. Potapov, Bart Meyns, Mustafa Özbaran, David Schibilsky, Kadir Caliskan, the EUROMACS investigators

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