Opioid sparing anesthesia in patients with liver cirrhosis undergoing liver resection: a controlled randomized double-blind study by Eman Sayed Ibrahim, Ahmed A. Metwally, Mohamed Abdullatif, Essam A. Eid, Mahmoud G. Mousa, Amany A. Sultan

“…We excluded patients with renal or cardiac dysfunction or contraindications from study medications.46 patients in the opioid-sparing group (OS) receiving ketamine and dexmedetomidine infusions and 46 patients in the opioid-based (OB) group as controls. …”
Get full text

Secukinumab in the treatment of psoriatic arthritis: efficacy and safety results through 3 years from the year 1 extension of the randomised phase III FUTURE 1 trial by Philip J Mease, Arthur Kavanaugh, Andreas Reimold, Hasan Tahir, Jürgen Rech, Stephen Hall, Piet Geusens, Pascale Pellet, Evie Maria Delicha, Shephard Mpofu, Luminita Pricop

“…Exposure-adjusted incidence rates for selected adverse events per 100 patient-years (secukinumab 150/75 mg) were serious infections (1.7/1.6), Candida infections (1.4/0.7), Crohn’s disease (0/0.3), ulcerative colitis (0/0.3) and major adverse cardiac events (0.3/0.8).Conclusion Subcutaneous secukinumab provided sustained improvements in the signs and symptoms, quality of life and physical function of patients with active PsA with low rate of radiographic disease progression through 3 years. …”
Get full text

Fabry cardiomyopathy: Gb3‐induced auto‐reactive panmyocarditis requiring heart transplantation by Andrea Frustaci, Maurizio Scarpa, Rosalia Maria da Riol, Chiara Agrati, Nicoletta Finato, Romina Verardo, Claudia Grande, Cristina Chimenti, Concetta Di Nora, Matteo Antonio Russo, Ugolini Livi

“…Aim of the study is to report a Gb3‐induced auto‐reactive panmyocarditis causing inefficacy of ERT and severe electrical instability, which required cardiac transplantation. Examining the explanted heart from a 57‐year‐old man with FD cardiomyopathy (CM) on 3‐year ERT presenting incoming ventricular fibrillation, we documented a severe virus‐negative myocarditis extended to cardiomyocytes, intramural coronary vessels, conduction tissue, and subepicardial ganglia. …”
Get full text

Outcomes of Worsened Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Replacement by Hu Z, Wang C, Luo S, Yang B, Zheng S, Hu X, Sun Y, Chen J, Fu M, Fan R, Luo J, Li J

“…Ziyang Hu,1,* Changjin Wang,2,* Songyuan Luo,2,* Bangyuan Yang,2 Shengneng Zheng,3 Xiaolu Hu,2,4 Yinghao Sun,2 Jiaohua Chen,2 Ming Fu,2 Ruixin Fan,5 Jianfang Luo,2,4 Jie Li2 1Department of Cardiology, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 3Department of Radiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 4School of Medicine South China University of Technology, Guangzhou, People’s Republic of China; 5Department of Cardiac Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Li; Jianfang Luo, Guangdong Provincial People’s Hospital, #96 Dongchuan Road, Yuexiu District, Guangzhou, Guangdong, 510080, People’s Republic of China, Tel +86 020 83827812, Email leomoku1981@163.com; jianfangluo@sina.comBackground: Left ventricular ejection fraction (LVEF) worsening after transcatheter aortic valve replacement (TAVR) was common in clinical practice. …”
Get full text

Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction by Yize Sun, Yize Sun, Haibin Zhao, Zheyi Wang

“…BackgroundPatients with myocardial infarction (MI) have a high incidence of depression, which deteriorates the cardiac function and increases the risk of cardiovascular events. …”
Get full text

Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation by Xiaoyu Yu, Weiwei Wu, Jingjun Hao, Yuxin Zhou, Deyang Yu, Wei Ding, Xuejuan Zhang, Gaoli Liu, Jianxun Wang

Get full text

Effectiveness and safety of an emergency department-based rapid response system by Fanny Delfanti, Guido Bertolini, Giovanni Nattino, Giulia Acquistapace, Daniela De Palma, Piergiuseppe Ferrari, Sara Martinenghi, Stefano Maiandi, Marco Rossi, Anna Lilia Ruocco, Maria Teresa Spina, Benedetta Chiodi, Stefano Paglia

“…Rapid Response Systems (RRSs) are designed to assist hospitalized patients who become unstable, aiming to address “failure to rescue” and prevent cardiac arrests. Despite global implementation, evidence of RRS effectiveness is controversial. …”
Get full text

Analysis of chronic kidney disease epidemiology in Kazakhstan using nationwide data for 2014–2020 and forecasting future trends of prevalence and mortality for 2030 by Gulnur Zhakhina, Kamilla Mussina, Sauran Yerdessov, Arnur Gusmanov, Yesbolat Sakko, Valdemir Kim, Dmitriy Syssoyev, Meruyert Madikenova, Ainur Assan, Zhanat Kuanshaliyeva, Duman Turebekov, Kuanysh Yergaliyev, Bolat Bekishev, Abduzhappar Gaipov

Get full text

The importance of the Autostrain RV technique in the treatment of right ventricular myocardial alterations in patients with breast cancer receiving chemotherapy by Yan Liang, Ping Du, Yabo Song, Xinshi Li, Yingying Han, Hongfang Dongye, Hongqiang Liu, Jinqiu Li

“…To examine the changes in various cardiac function parameters before and after chemotherapy, two-dimensional echocardiography was employed 48 h before chemotherapy, 48 h after the fourth cycle of chemotherapy, and 48 h after the eighth cycle of chemotherapy, respectively. …”
Get full text

Outcome of Newborns with Tracheoesophageal Fistula: An Experience from a Rapidly Developing Country: Room for Improvement by Amal Al-Naimi, Sara G. Hamad, Abdalla Zarroug

“…All patients were operated except for one patient who died at 2 days of life due to cardiac complications. Median age at which surgery was performed was 2 days (range 1-270 days). …”
Get full text

Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy by Putriana NA, Latarissa IR, Rusdiana T, Rostinawati T, Akbar MR

“…Therefore, this research aimed to evaluate the impact of clinical and genetic factors on warfarin dose adjustment and to develop a dosing algorithm for patients with cardiovascular disease.Patients and Methods: A total of 77 research subjects were selected using consecutive sampling based on the inclusion criteria of cardiac outpatients on warfarin for ≥ 3 months with PT-INR data, complete medical records, and willingness to participate. …”
Get full text

Analysis of Atrial Fibrillation Treatment Regimes in a Multicenter Cohort of Transcatheter Edge-to-Edge Mitral Valve Repair Patients by Christian Waechter, Felix Ausbuettel, Georgios Chatzis, Dieter Fischer, Holger Nef, Sebastian Barth, Philipp Halbfaß, Thomas Deneke, Sebastian Kerber, Dimitar Divchev, Bernhard Schieffer, Ulrich Luesebrink

“…The prevalence of concomitant AF was 73.3%, and AF did not affect the procedural success or the incidence of major adverse cardiac and cerebrovascular events. The patients with AF were more frequently >75 years, had more tricuspid regurgitation, and less coronary artery disease than non-AF patients. …”
Get full text

Effectiveness of mobile health for exercise promotion on cardiorespiratory fitness after a cancer diagnosis: A systematic review and meta‐analysis by Megan E. Gregory, Weidan Cao, Saurabh Rahurkar, Fadi Haroun, James C. Stock, Sanam M. Ghazi, Daniel Addison

“…Included studies provided a quantitative evaluation of an mHealth intervention in a primary or secondary capacity on cardiorespiratory fitness (6‐minute walk test, VO2max, 3‐minute step test, or systolic blood pressure; or any mention of cardiac measure) and were meta‐analyzed (using a random effects model) if they were a randomized controlled trial with sufficient quantitative information. …”
Get full text

Knowledge, attitudes, and beliefs regarding acute coronary syndrome in patients with type 2 diabetes: a cross-sectional study by Mohammad Amerzadeh, Mahdie Bahrami, Mojtaba Senmar, Zahra Hosseinkhani, Zahra Shafiei Kisomi

“…Abstract Introduction Cardiovascular diseases are one of the leading causes of mortality and disability among individuals with diabetes. Cardiac mortality in these patients is often associated with the prevalence of silent ischemia. …”
Get full text

Nursing of a patient undergoing trans-apical transcatheter aortic valve replacement for severe aortic insufficiency (心尖途径经导管主动脉瓣置换术治疗重度主动脉瓣关闭不全1例护理体会)... by XU Yuanhua (徐远华), HE Hui (何慧), ZHAO Jianhua (赵建华), DENG Zibin (邓梓彬), ZOU Minghui (邹明辉), YANG Yang (杨扬), PAN Gang (潘港)

“…A comprehensive nursing process was established, including early psychological intervention to alleviate negative emotions, preoperative evaluation and preparation by a multidisciplinary team, close monitoring of the patient's condition and team cooperation during surgery, refined postoperative care, and staged cardiac rehabilitation training. The comprehensive nursing plan was conducted to ensure the success of surgery and improve postoperative recovery of the patient. …”
Get full text

Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…The first was a non-invasive risk calculator which included NT-proBNP and FVC%/DLCO%, and a second adds cardiac index, an invasive parameter, to the above two parameters. …”
Get full text

Lesbian, gay, bisexual, and transgender clinical competence of health professionals in Poland and Spain: results of the health exclusion research in Europe (HERE) study by Piotr Karniej, Anthony Dissen, Łukasz Pietrzykowski, Raúl Juárez-Vela, Antonio Martinez Sabater, Janina Kulińska, Jakub Zieliński, Michał Czapla

Get full text

Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches by Hui Qu, Bao-dong Xie, Jian Wu, Bo Lv, Jun-bo Chuai, Jian-zhong Li, Jun Cai, Hua Wu, Shu-lin Jiang, Xiao-ping Leng, Kai Kang

“…After 4 weeks, the rats repaired with this cell-seeded, cytokine-immobilized patch presented preserved cardiac function, beneficial morphology, enhanced cell infiltration, and functional vessel formation compared with the cytokine-free (MSC patch), cell-free (GF patch), or blank controls (EDC patch). …”
Get full text

The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…There were 176 (13.9%) deaths in total including 89 cardiac/vascular deaths during follow-up. Cox regression analysis showed that ERI was positively associated with all-cause mortality, especially in some subgroups. …”
Get full text

Men's more frequent predisposing factors in infectious endocarditis facilitate improvement of outcomes by shortening of diagnostic delay by S. Andreß, K. Reischmann, S. Markovic, F. Rohlmann, B. Hay, W. Rottbauer, D. Buckert, S. d'Almeida

“…Men exhibited a higher prevalence of predisposing cardiac conditions (p = 0.012) due to a higher frequency of a history of implantable cardioverter defibrillator implantation (p = 0.004), and were more likely to have poor dental status (p = 0.001), and coronary artery disease (p = 0.002). …”
Get full text