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Urothelial Cancer Stem Cells
Published 2010-01-01“…There is mounting evidence supporting the idea that tumors, similar to normal adult tissues, arise from a specific stem-like cell population, the cancer stem cells (CSCs), which are considered as the real driving force behind tumor growth, the ability to metastasize, as well as resistance to conventional antitumor therapy. …”
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Ovarian Epithelial Cancer Stem Cells
Published 2011-01-01“…The last decade witnessed an explosion of interest in cancer stem cells (CSCs). The realization of epithelial ovarian cancer (EOC) as a CSC-related disease has the potential to change approaches in the treatment of this devastating disease dramatically. …”
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Advances and Challenges in Cancer Stem Cells for Onco-Therapeutics
Published 2023-01-01“…The strategy of targeting cancer stem cells is beset with challenges, including immune rejection and disease relapse. …”
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Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications
Published 2017-01-01“…Tumor consists of heterogeneous cancer cells including cancer stem cells (CSCs) that can terminally differentiate into tumor bulk. …”
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Renal Cancer Stem Cells: Characterization and Targeted Therapies
Published 2016-01-01“…Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells, and cancer stem cells (CSCs). CSCs possess two main properties: self-renewal and proliferation. …”
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Detection of Cancer Stem Cells from Patient Samples
Published 2025-01-01Subjects: “…cancer stem cell (CSC)…”
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Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment
Published 2017-01-01“…Specifically, aberrant activation of these pathways is implicated in modulation of cancer stem cells (CSCs), a small subset of cancer cells capable of self-renewal and differentiation into heterogeneous tumor cells. …”
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The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells
Published 2016-01-01“…Several studies have shown that pancreatic cancer stem cells (PCSCs) play different roles in the regulation of drug resistance and recurrence in pancreatic cancer. …”
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The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells
Published 2016-01-01“…Several studies demonstrated that hepatic cancer stem cells (HCSCs), also called tumor-initiating cells, are involved in regulation of HCC initiation, tumor progression, metastasis development, and drug resistance. …”
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Wnt5a Signaling in Normal and Cancer Stem Cells
Published 2017-01-01“…Recent studies show the involvement of Wnt5a signaling in regulating normal and cancer stem cell self-renewal, cancer cell proliferation, migration, and invasion. …”
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Research on ovarian cancer stem cells based on bibliometric analysis
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Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis
Published 2018-01-01“…However, a highly dynamic equilibrium was found between cancer stem cells and cancer cells, and this indicates that cancer stem cells are no more special target and blocking the transformation of cancer stem cells and cancer cells seem to be a more significant therapy strategy. …”
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Chemoresistance, Cancer Stem Cells, and miRNA Influences: The Case for Neuroblastoma
Published 2015-01-01“…This review focuses on highlighting the recent, important implications of miRNAs within the context of neuroblastoma basic research efforts, particularly concerning miRNA influences on cancer stem cell pathology and chemoresistance pathology for this condition, together with development of translational medicine approaches for novel diagnostic tools and therapies for this neuroblastoma.…”
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On a mathematical model of tumor growth based on cancer stem cells
Published 2012-11-01“…We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution ofdifferent subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. …”
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Exosomal insights into ovarian cancer stem cells: revealing the molecular hubs
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Bladder Cancer and Cancer Stem Cells: Basic Science and Implications for Therapy
Published 2011-01-01“…The recently identified bladder cancer stem cells are considered to be mediators of resistance to current therapies and therefore represent strong candidate biological targets. …”
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The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment
Published 2017-01-01“…There is evidence that a small population of cells within the tumors called cancer stem cells (CSCs) could be responsible for treatment failure due to their enhanced chemoresistance and tumorigenicity. …”
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Corrigendum to “Wnt5a Signaling in Normal and Cancer Stem Cells”
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A Review of Stem Cell Translation and Potential Confounds by Cancer Stem Cells
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True cancer stem cells exhibit relative degrees of dormancy and genomic stability
Published 2025-02-01Subjects: “…Cancer stem cells…”
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