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12581
Epithelial–Mesenchymal Transition Suppression by ML210 Enhances Gemcitabine Anti-Tumor Effects on PDAC Cells
Published 2025-01-01“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in the world. Neoadjuvant chemotherapy (NAC) has become a standard treatment for patients scheduled for surgical resection, but the high rate of postoperative recurrence is a critical problem. …”
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12582
Production of Prodigiosin Using Tannery Fleshing and Evaluating Its Pharmacological Effects
Published 2014-01-01“…IC50 concentration was cell line specific (HeLa cells: 4.3 µM, HEp2: 5.2 µM, and KB cells: 4.8 µM) and remains nontoxic up to the concentration of 25 µM on normal Vero cells suggesting that cancerous cells are more susceptible to the prodigiosin at lower concentration. …”
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12583
Ovarian Carcinosarcoma and Its Association with Mature Cystic Teratoma and Primary Tubal Carcinoma
Published 2016-01-01“…Carcinosarcoma is an uncommon form of ovarian cancers, classified as being part of the group of mixed epithelial and mesenchymal tumors. …”
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12584
Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors
Published 2025-03-01“…We found that in pNET development and metastasis, 11 genes and 14 circRNAs were notably upregulated, while 25 genes and 35 circRNAs were significantly downregulated, compared to nearby non-cancerous tissue. Our analysis of differentially expressed RNA and circRNA genes revealed that tumor cell adhesion and integrin activation, regulated by genes like PIEZO1, IFT74, SKAP1, GPX1, F7, VTN, and OMG, are strongly linked to pNET metastasis. …”
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12585
Double Stokes polarimetric microscopy for chiral fibrillar aggregates
Published 2025-02-01“…DSP can be applied to investigate the origin of chiral complex-valued susceptibility of collagen, to study modifications of collagen in cancerous tissue, and to map ultrastructural parameters of large areas for whole-slide histopathology.…”
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12586
Technique of Coaxial Frame in Reflection for the Characterization of Single and Multilayer Materials with Correction of Air Gap
Published 2014-01-01“…Techniques based on fixture probes in reflection are used in microwave reflectometry as a novel diagnostic tool for detection of skin cancers, for complex permittivity measurements on liquid samples and oil shale, and for complex dielectric permittivity of animals’ organs and tissues measurements in microwave band for the needs of modern veterinary medicine. …”
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12587
A Papillary Thyroid Microcarcinoma Revealed by a Single Bone Lesion with No Poor Prognostic Factors
Published 2013-01-01“…Thyroid carcinomas incidence, in particular papillary variants, is increasing. These cancers are generally considered to have excellent prognosis, and papillary microcarcinomas are usually noninvasive. …”
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12588
Breast Diffuse Large B-cell Lymphoma, Activated B-cell like Subtype: A Case Report
Published 2025-01-01“…Primary Breast Lymphoma (PBL) is an uncommon form of Non Hodgkin Lymphoma (NHL) that arises within the breast tissue, representing less than 1-2% of all cases of NHL and under 0.5% of all breast cancers. Most PBL cases are of the B-cell type, accounting for up to 50% of all PBL. …”
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12589
Diagnosis and Treatment of Mucinous Appendiceal Neoplasm Presented as Acute Appendicitis
Published 2016-01-01“…Ultrasound and CT are useful in diagnosing appendiceal mucocele and synchronous cancers in the emergency setting. The initial operation should include appendectomy and resection of the appendicular mesenteric fat along with any fluid collection for cytologic examination. …”
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12590
Long Term Survival and Continued Complete Response of Vemurafenib in a Metastatic Melanoma Patient with BRAF V600K Mutation
Published 2016-01-01“…Main toxicities reported were grade 1 photosensitivity and skin cancers. Vemurafenib was discontinued but patient remains disease free 12 months after stopping treatment and the clinical review is ongoing. …”
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12591
The Evolution of Dendritic Cell Immunotherapy against HIV-1 Infection: Improvements and Outlook
Published 2020-01-01“…The advancements in dendritic cell vaccines in cancers have paved the way for applications of this form of immunotherapy to HIV-1 infection. …”
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12592
Gene Therapy Approaches
Published 2021-03-01“…For human use in genetic conditions, cancers and acquired illnesses, gene transfer techniques have been allowed. …”
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12593
Understanding cultural perceptions of sexuality in China and their influence on human papillomavirus vaccine hesitancy
Published 2025-01-01“…IntroductionThe human papillomavirus (HPV) vaccine prevents infections that may result in precancerous lesions, cervical cancers, genital warts, and many other diseases. However, its uptake rate in China is 2.24%, and HPV vaccine hesitancy is widespread. …”
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12594
Single-cell RNA sequencing reveals tumor heterogeneity in small cell neuroendocrine cervical carcinoma
Published 2025-02-01“…Here, we mapped the single-cell landscape of a total of six samples from matched SCNECC cancerous foci and normal adjacent cervical tissues. …”
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12595
Genetics and Molecular Biology of Epstein-Barr Virus-Encoded BART MicroRNA: A Paradigm for Viral Modulation of Host Immune Response Genes and Genome Stability
Published 2017-01-01“…Epstein-Barr virus, a ubiquitous human herpesvirus, is associated through epidemiologic evidence with common autoimmune syndromes and cancers. However, specific genetic mechanisms of pathogenesis have been difficult to identify. …”
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12596
Comprehensive Overview - Outcomes and Challenges of Bariatric Surgery - Physical, Psychological and Nutritional Considerations
Published 2025-02-01“… Obesity, defined by excessive and abnormal body fat accumulation, leads to various health conditions such as diabetes, cardiovascular diseases, and certain cancers, significantly affecting the health and increasing the risk of mortality. …”
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12597
Investigating neutropenic enterocolitis: a systematic review of case reports and clinical insights
Published 2025-01-01“…Most cases occur in patients with hematological cancers undergoing chemotherapy. Common presentations include abdominal pain, fever, and diarrhea. …”
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12598
Effect of Esophageal Endoscopic Submucosal Dissection on Motility and Symptoms: A Prospective Study
Published 2018-01-01“…Twenty-eight patients with 35 cT1a cancers were prospectively enrolled between December 2014 and February 2016. …”
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12599
Ethnobotanical survey of medicinal and aromatic plants used by the population of Settat Province, Morocco
Published 2025-02-01“…The results highlighted the primary ailments treated with these plants, such as diabetes, gastrointestinal disorders, cardiovascular diseases, oral conditions, cancers, insomnia, and stress. Additionally, the study referenced traditional medicinal uses from various national studies and international scientific research that validated the therapeutic properties of each plant.…”
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12600
Physical activity at home during the COVID-19 lockdown in India: Need of the hour for optimum physical health and psychological resilience
Published 2020-07-01“…It can reduce high blood pressure, help manage overweight, improve immune regulation, reduce the risk of getting heart disease, type 2 diabetes, stroke, and various cancers- all conditions which increase vulnerability to COVID-19. …”
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