Reversing NK cell exhaustion: a novel strategy combining immune checkpoint blockade with drug sensitivity enhancement in the treatment of hepatocellular carcinoma by Yuxiang Huang, Hengjian Liao, Jiefu Luo, Huaning Wei, Anling Li, Yujie Lu, Bangde Xiang

“…Hepatocellular carcinoma (HCC) is one of the most common lethal cancers worldwide. Natural killer cells (NK cells) play a key role in liver immunosurveillance, but in the tumor microenvironment, NK cells are readily depleted, as evidenced by down-regulation of activating receptors, reduced cytokine secretion, and attenuated killing function. …”
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Oxidative stress: an overview of past research and future insights by Aaser M. Abdelazim, Mosleh M. Abomughaid

“…The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. …”
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Erdheim-Chester Disease and Small Lymphocytic Lymphoma Collision Tumour Presenting as a Perirenal Mass by Antonio Maietta, Maryam Razmpoosh

“…Erdheim-Chester disease rarely can be associated with other cancers, namely myeloid neoplasms. We report a case of Erdheim-Chester disease presenting with small lymphocytic lymphoma as a perirenal mass. …”
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Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm by S. Saltsberger, I. Steinberg, I. Gannot

“…Such changes are related with cancerous processes within the cell as well as other cell pathologies. …”
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Facts about Antioxidants by Kaitlin G. Clark, Wendy J. Dahl

“…Antioxidants also can help our immune system defend against bacteria, fungi, viruses, and some cancers. The body produces some of its own antioxidants, but eating a plant-based diet increases the level of antioxidants in our bodies. …”
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Facts about Antioxidants by Kaitlin G. Clark, Wendy J. Dahl

“…Antioxidants also can help our immune system defend against bacteria, fungi, viruses, and some cancers. The body produces some of its own antioxidants, but eating a plant-based diet increases the level of antioxidants in our bodies. …”
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Urachal Tumor: A Case Report of an Extremely Rare Carcinoma by José Palla Garcia, Rita Sampaio, Carlos Peixoto

“…The urachus carcinoma is an extremely rare tumor that accounts for <1% of all bladder cancers. We report a case of a 46-year-old woman, with no past medical history, complaining of hematuria with 6-month duration and a physical exam and an abdominal computed topographic scan revealing an exophytic mass of 6.8 cm longer axis that grew depending on the anterior bladder wall, invading the anterior abdominal wall. …”
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Long Non-coding RNA: Characterizing the Locus Features by the Approaches by Mohammadreza Hajjari, Saghar Rahnama

“…HOTAIR is an lncRNA that has been known to have an oncogenic role in different cancers. There is limited knowledge of genetic and epigenetic elements and their interactions for the gene encoding HOTAIR. …”
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The Role of Bridging Therapy in Hepatocellular Carcinoma by Roberto Galuppo, Angie McCall, Roberto Gedaly

“…Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver accounting for 7% of all cancers worldwide. Most cases of HCC develop within an established background of chronic liver disease. …”
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A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx by Harry Boamah, Billy Ballard

“…Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. …”
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Composite submental flaps in facial reconstructive surgery involving the zygoma and orbit by Usman Khan, Sebastian Haupt, Matthew Rigby, S. Mark Taylor, Martin Corsten, Jonathan Trites

“…All were performed following resection of skin cancers with invasion of the upper facial skeleton. …”
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Multiple Low Energy Long Bone Fractures in the Setting of Rothmund-Thomson Syndrome by Nicholas Beckmann

“…Rothmund-Thomson syndrome is a rare autosomal recessive genodermatosis characterized by a poikilodermatous rash starting in infancy as well as various skeletal anomalies, juvenile cataracts, and predisposition to certain cancers. Although Rothmund-Thomson syndrome is associated with diminished bone mineral density in addition to multiple skeletal abnormalities, there are few reports of the association with stress fractures or pathologic fractures in low energy trauma or delayed healing of fractures. …”
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A New Challenging Strategy in the Prevention and Management of Tumor Lysis Syndrome in Patients with Chemo-Sensitive Hematological Malignancies by Ammar ELJack, Mohamad El Abdallah, Kadhim Al-Banaa, Kashif Chaudhry, Faisal Musa

“…It happens frequently in cancers receiving chemotherapy, particularly hematological malignancies. …”
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Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors by Runhan Liu, Jiaxin Zhou, Xiaochen Chen, Jie Zhang, Qunzhi Chen, Xiaoming Liu, Kunhou Yao

“…This review provides a narrative examination of the diagnostic and therapeutic potential of RNA in gastrointestinal cancers, with an emphasis on its application in precision medicine. …”
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Contrast-Enhanced Mammography in the Diagnosis of Breast Angiosarcoma by Maya Grisaru Kacen, Nikhil Sangle, Anat Kornecki

“…Breast angiosarcoma is a rare entity that represents less than 1% of all breast cancers. To our knowledge, this is the first case describing the imaging findings of breast angiosarcoma on contrast-enhanced mammography.…”
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Hedgehog pathway inhibitors (HHI) combined with radiotherapy and immunotherapy for advanced basal cell carcinoma: a case report by Zhuren Ruan, Chen Zhao, Longshan Li, Xianghui Li, Zhijian Yao, Gao Wei

“…Purpose Basal cell carcinoma (BCC) is one of the most common skin cancers. Most BCCs can be treated with surgery excision. …”
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Heterogeneity of Genetic Landscapes in Salivary Gland Tumors and Their Critical Roles in Current Management by Anam YOUSAF, Sarina SULONG, Baharudin ABDULLAH, Norhafiza Mat LAZIM

“…This review presents the most recent advances in the molecular pathology of salivary gland cancers, with an emphasis on distinguishing molecular features that can be used for optimizing current patient management.…”
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Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking by In Won Lee, Jonghwan Yoon, Gunhee Lee, Minho Lee

“…Apurinic/apyrimidinic endonuclease 1 (APE1) is an enzyme responsible for the initial step in the base excision repair pathway and is known to be a potential drug target for treating cancers, because its expression is associated with resistance to DNA-damaging anticancer agents. …”
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A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk by Lewei Duan, Duncan C. Thomas

“…The method is applied to data on 504 SNPs in 38 candidate genes involved in DNA damage response in the WECARE study of second breast cancers in relation to radiotherapy exposure.…”
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Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma by Yun Cao, Wei Zhang, Yi-Ting Jin, Qiang Zou

“…Heterogeneous nuclear ribonucleoproteins (HNRNPs) are crucial members in the pathogenesis and progression of numerous cancers. However, the expression pattern and clinical significance of HNRNPs in breast carcinoma (BC) remain to be investigated. …”
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