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Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L.
Published 2025-01-01“…Similarly, PR10 expression showed moderate upregulation in S15 and significantly higher levels in SP15, reflecting enhanced pathogen defense. Calmodulin (CAL) gene expression was moderately regulated in S15 but significantly amplified in SP15. …”
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42
Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway
Published 2025-01-01“…Additionally, we performed immunoblotting to quantify the expression of DHCR24, total calmodulin-dependent protein kinase 2 (CAMK-2), p-CAMK2 (T286), caveolin-1, total synapsin-1, phosphorylated synapsin-1 (p-synapsin-1; S605), and synaptophysin in each experimental group. …”
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43
β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis
Published 2024-12-01“…We analyzed blood urea nitrogen (BUN) and creatinine (Cr) levels in serum, and used western blotting and immunohistochemical staining to assess ferroptosis and the calcium/calmodulin-dependent kinase kinase 2 (Camkk2)/AMPK pathway. …”
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44
Goose astrovirus induces apoptosis and endoplasmic reticulum stress in gosling hepatocytes
Published 2025-01-01“…RT-qPCR and Western blot analyses indicated that GoAstV infection enhanced the expression of ER Ca2+ release channels (IP3R and RYR) and calmodulin-dependent protein kinase II (CaMKII), while decreasing the expression of ER Ca2+ uptake channels (SERCA). …”
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45
Mannogalactoglucan from mushrooms protects pancreatic islets via restoring UPR and promotes insulin secretion in T1DM mice
Published 2024-05-01“…Besides that, AAMP-N promoted insulin synthesis via upregulating the expression of transcription factors, increased Ca2+ signals to stimulate intracellular insulin secretory vesicle transport via activating calcium/calmodulin-dependent kinase II (CamkII) and cAMP/PKA signals, and enhanced insulin secretory vesicle fusion with the plasma membrane via vesicle-associated membrane protein 2 (VAMP2). …”
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46
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Abstract Background Death-Associated Protein Kinase 1 (DAPK1) family members are calcium/calmodulin-regulated serine/threonine kinases implicated in cell death, normal development, and human diseases. …”
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47
Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons
Published 2025-02-01“…M1R antagonism stimulated TRPM3 channel activity through inhibition of PIP2 hydrolysis to activate Ca2+/calmodulin-dependent protein kinase kinase β (CaMKKβ)/AMPK, leading to augmented mitochondrial function and neuronal metabolism. …”
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48
The SIRT5-JIP4 interaction promotes osteoclastogenesis by modulating RANKL-induced signaling transduction
Published 2025-01-01“…RANKL-induced signaling has been analyzed in detail, and the involvement of TNF receptor-associated factor 6 (TRAF6), calmodulin-dependent protein kinase (CaMK), NF-κB, mitogen-activated protein kinase (MAPK), activator protein-1 (AP-1), and molecules that contain an immunoreceptor tyrosine-based activation motif (ITAM) has been reported. …”
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49
New Species of <i>Diaporthales</i> (<i>Ascomycota</i>) from Diseased Leaves in Fujian Province, China
Published 2024-12-01“…Based on morphological features coupled to multigene phylogenetic analyses of the internal transcribed spacer (ITS) region, the large subunit of nuclear ribosomal RNA (LSU), the partial beta-tubulin (<i>tub2</i>), histone H3 (<i>his3</i>), DNA-directed RNA polymerase II subunit (<i>rpb2</i>), translation elongation factor 1-α (<i>tef1</i>) and calmodulin (<i>cal</i>) genes, three new species of <i>Diaporthales</i> are introduced, namely, <i>Diaporthe wuyishanensis</i>, <i>Gnomoniopsis wuyishanensis</i> and <i>Paratubakia schimae</i>. …”
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50
CaMKII-dependent non-canonical RIG-I pathway promotes influenza virus propagation in the acute-phase of infection
Published 2025-01-01“…ABSTRACT Ca2+/calmodulin-dependent protein kinase II (CaMKII) is one of hundreds of host-cell factors involved in the propagation of type A influenza virus (IAV), although its mechanism of action is unknown. …”
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