Early Decrease in Respiration and Uncoupling Event Independent of Cytochrome c Release in PC12 Cells Undergoing Apoptosis by Libera Berghella, Elisabetta Ferraro

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Cytokines and Liver Diseases by Herbert Tilg

“…Among the various cytokines, the proinflammatory cytokine tumour necrosis factor-alpha (TNF-a) has emerged as a key factor in various aspects of liver disease, such as cachexia and/or cholestasis. Thus, antagonism of TNF-a and other injury-related cytokines in liver diseases merits evaluation as a treatment of these diseases. …”
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Study of experimentally infected cattle and sheep sensitivity to lumpy skin disease by M. S. Kukushkina, O. A. Ryabikina, A. V. Kononov, V. I. Diev

“…It was established that cattle is more sensitive to LSDV in comparison to sheep: the disease in cattle was severe with fever, anorexia, cachexia and nodule development. Sheep reacted to virus inoculation with the development of nodules and swelling in the site of virus suspension injection, conjunctivitis, short-term anorexia and fever during 3-5 days post infection. …”
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Mange in Rabbits: An Ectoparasitic Disease with a Zoonotic Potential by Wafaa A. Abd El-Ghany

“…The skin affection is characterized by pruritus, alopecia, severe cachexia, and sometimes death. Infestation is diagnosed mainly by skin scraping and microscopic examination. …”
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Mortality Associated with Recurrent Extreme Hyperferritinemia in Critically Ill Adolescents by John Scott Baird

“…Lymphocytopenia and cachexia were noted in all patients. Conclusions. Recurrent extreme hyperferritinemia—often with multiple organ dysfunction syndrome—was noted in 4 adolescents with systemic inflammation who did not survive their critical illness. …”
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Plasmacytoid Urothelial Carcinoma of the Urinary Bladder Metastatic to the Duodenum: A Case Report—Diagnostic Relevance of GATA3 Immunohistochemistry by Hermann Brustmann

“…The patient died eleven months after the primary diagnosis of his PUC of tumor cachexia losing about 50% of his original body weight, furthermore, with ascites and intraperitoneal tumor spread.…”
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Break through the mold: Hyper-IgE syndrome as a vehicle for invasive aspergillosis by Joseph Nordin, Stephen Smetana, Rachel Johnson, Angela Bartosiak, Nicholas Nassif

“…This case describes a 70-year-old male with cachexia and dyspnea found to have a cavitary lesion and aspergilloma, with remarkably high IgE and positive 1,3-β-D-glucan and Aspergillus testing. …”
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MIGRAÇÕES, MOLÉSTIAS, SOBREVIVÊNCIAS: CEARENSES E PIAUIENSES NA SANTA CASA DE MISERICÓRDIA (TERESINA-1879) by Márcio Douglas de Carvalho e Silva

“…As moléstias mais frequentes eram febre intermitente, febre paludosa, cachexia paludosa, úlceras, vermes e diarreias. Observou-se extensos períodos de internação, o que permitiu levantar hipóteses acerca das estratégias de sobrevivência da população pobre e migrante.…”
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Graft-versus-Host Disease after Living-Unrelated Kidney Transplantation by N. Zacharias, M. H. Gallichio, D. J. Conti

“…At this point he was transferred to our center with a BMI of 16 and severe cachexia. Intravenous hyperalimentation was initiated and an extensive work-up for an infectious etiology was performed and was negative. …”
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Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child by Y. T. Udaka, K. Shayan, N. A. Chuang, J. R. Crawford

“…Examination revealed extreme cachexia, gaze-evoked nystagmus, dysphagia, dysarthria, bilateral dysmetria, and global weakness without ambulation. …”
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Intra-Abdominal Localisation of a Buschke-Lowenstein Tumour: Case Presentation and Review of the Literature by N. E. Wester, E. M. Hutten, C. Krikke, Robert A. Pol

“…Treatment was impeded by cachexia, an immunosuppressive state after kidney transplantation and difficulties in establishing a reliable diagnose. …”
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Early Detection of Pancreatic Cancer: Opportunities Provided by Cancer-induced Paraneoplastic Phenomena and Artificial Intelligence by Wei-Chih Liao

“…Paraneoplastic syndromes, including pancreatic cancer-associated diabetes and cachexia, are prevalent in PDAC patients and may provide windows of opportunity for early detection. …”
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Mitochondrial Neurogastrointestinal Encephalomyopathy: Novel Pathogenic Mutation in Thymidine Phosphorylase Gene in a Patient from Cape Verde Islands by Catarina Falcão de Campos, Miguel Oliveira Santos, Rafael Roque, Isabel Conceição, Mamede de Carvalho

“…It is clinically characterized by severe gastrointestinal dysmotility, cachexia, palpebral ptosis, ophthalmoparesis, sensorimotor polyneuropathy and leukoencephalopathy. …”
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A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer by David G. Watt, Campbell S. Roxburgh, Mark White, Juen Zhik Chan, Paul G. Horgan, Donald C. McMillan

“…Of those invited by the survey (n=238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. …”
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The relationship of growth differentiation factor 15 with some biochemical parameters in cardiovascular disease patients in Babylon City by Hiba Resheed Behayaa, Zinah Abbass Ali, Seenaa Badr Mohammed, Suhayr A. Alqaysi

“…Growth differentiation factor 15 (GDF15) is about cachexia, CVD, and a lot of inflammatory diseases. …”
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An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease by Kalliopi Azariadis, Maria Ioannou, Kalliopi Zachou, George N. Dalekos

“…We present an 82-year-old immunocompetent male patient who was admitted to our department because of low-grade fever, cachexia, anasarca, hepatosplenomegaly, and generalized lymphadenopathy. …”
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Arrested Puberty in an Adolescent Male with Anorexia Nervosa Successfully Resumed with Multidisciplinary Care by Diana Simão Raimundo, Carolina Figueiredo, Ana Raposo, Bernardo Dias Pereira

“…Past medical history was relevant for asthma. Generalized cachexia, facial lanugo hair, cutaneous xerosis, and Russell’s sign were noted; he had a height of 155.5 cm (−2.5 SD; target height: 168 cm, −1.1 SD) and a BMI of 12.4 kg/m2 (−6.8 SD); left and right testicular volumes were 8 mL and 10 mL, respectively. …”
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Substrains of Inbred Mice Differ in Their Physical Activity as a Behavior by Dario Coletti, Emanuele Berardi, Paola Aulino, Eleonora Rossi, Viviana Moresi, Zhenlin Li, Sergio Adamo

“…Spontaneous activity persists in pathological conditions, such as cancer-associated cachexia. This important amount of physical activity results in a minor muscle adaptation to endurance exercise over a three-week period; indeed, only a nonsignificant increase in NADH transferase+ fibers occurs in this time frame.…”
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Branched-Chain Amino Acids (BCAAs): Revisiting Their Role in Sport and Health by Aleksandra Kajtel, Anna Skowronek, Martyna Piekarska, Katarzyna Dąbek, Michał Ochwat, Maria Sudoł, Gabriela Mierzwa

“…This review explores the biochemistry, metabolism, and signaling pathways of BCAAs, emphasizing their potential therapeutic applications in conditions like sarcopenia, liver cirrhosis, and cachexia. BCAA metabolism primarily occurs in skeletal muscle and liver, with leucine activating key signaling pathways like mTORC1, promoting muscle growth and reducing protein breakdown. …”
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Energy intake insufficiency due to underestimated energy requirement by common predictive formulas can be identified by urinary amino acid levels in advanced heart failure by Yoko Sakamoto, Tomohito Ohtani, Kei Nakamoto, Fusako Sera, Shungo Hikoso, Yasushi Sakata

“…BackgroundElevated resting energy expenditure (REE) promotes cachexia, worsening prognosis in patients with advanced heart failure (HF). …”
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