Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring by Adam R. Evans, Joseph Mulholland, Michael J. Lewis, Ping Hu

“…Thus, removal of the IEC method from the DP specification was achieved using a validated LC-MS MAM method on a QDa system to directly measure the charge variant PTM CQAs in combination with size exclusion chromatography (SE-HPLC) and capillary electrophoresis (CE-SDS) to measure the non-PTM charge variant CQAs. Bridging data between the MAM, IEC, and SE-HPLC methods were included in the commercial marketing application to justify removing IEC from the DP specification. …”
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Intersection between individual, household, environmental and system level factors in defining risk and resilience for children in Kenya's ASAL: A qualitative study. by Esther Jebor Chongwo, Barack Aoko, Martha Kaniala, Moses Esala, Phillis Magoma, Eunice Njoroge, Susan Nyamanya, Joyce Marangu, Anil Khamis, John Ng'asike, Anja C Huizink, Amina Abubakar

“…This study aimed at bridging this gap.<h4>Methods</h4>The study was conducted in 10 ASAL counties in Kenya. …”
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Study on Damage Evolution of Tunnel Lining under Strike-Slip Fault Movements by Jiaxuan Du, Songhong Yan, Weiyu Sun, Mingxing Cao, Yuxiang Li, Kang Yang

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A comparative performance analysis of machine learning models for compressive strength prediction in fly ash-based geopolymers concrete using reference data by Muhammad Kashif Anwar, Muhammad Ahmed Qurashi, Xingyi Zhu, Syyed Adnan Raheel Shah, Muhammad Usman Siddiq

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The Effect of Community Based Intervention on People with Type 2 Diabetes Mellitus: Systematic Review by M Agung Akbar, Junaiti Sahar, Etty Rekawati, Ratu Ayu Dewi Sartika, Prateek Gupta

“…Nurses are encouraged to collaborate with community-based networks to bridge the gap between healthcare providers and communities, thereby enhancing public health outcomes. …”
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Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel by Erick B. Saldes, Alexandra Erdmier, Jai Velpula, Timothy E. Koeltzow, Michael X. Zhu, Swapna Asuthkar

“…<b>Conclusions:</b> These results should bridge the existing gaps in the knowledge regarding TRPM8 and inform potential targets for future studies to elucidate its role in the behavior changes and pathology of the diseases associated with TRPM8 activity.…”
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Lumbopelvic Stability and Trunk Muscle Contractility of Individuals with Chronic Ankle Instability by Ryan S McCann, Kelly Johnson, Ashley M B Suttmiller

“…Lumbopelvic stability was assessed using unilateral hip bridge, trunk flexion endurance, Biering-Sorensen, and side plank tests. …”
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Assessing the Sustainability of Southeast Asia’s Energy Transition: A Comparative Analysis by Faten Derouez, Adel Ifa

“…Existing studies often overlook the complex interplay between these factors, leaving a critical gap in understanding how tailored strategies can address country-specific dynamics. To bridge this gap, this study introduces the “Sustainable Energy-Environment Nexus” (SEEN) framework, which integrates economic growth, energy transitions, and environmental conservation as interconnected elements necessary for achieving carbon neutrality in both the short and long run. …”
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Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts by Fatima Jumare, Helen Ileigo Inabo, Muhammad Hassan Isa Doko, Gbonjubola Olusesan Adeshina

“…Background: Jatropha tanjorensis is a leafy vegetable widely consumed across Africa and is valued in folk medicine for its reputed blood-replenishing properties. This study aimed to bridge this research gap by assessing the acute oral toxicity, histopathological effects on vital organs, and chemo-suppressive antimalarial activity of J. tanjorensis leaf extracts, offering crucial insights into their therapeutic potential and safety profiles.Methods: Different extracts of J. tanjorensis leaves were obtained by sequential extraction via maceration. …”
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Nasal Dilators (Breathe Right Strips and NoZovent) for Snoring and OSA: A Systematic Review and Meta-Analysis by Macario Camacho, Omojo O. Malu, Yoseph A. Kram, Gaurav Nigam, Muhammad Riaz, Sungjin A. Song, Anthony M. Tolisano, Clete A. Kushida

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Interventions promoting recovery from depression for patients transitioning from outpatient mental health services to primary care: A scoping review. by Anne Sofie Aggestrup, Frederik Martiny, Line Lund Henriksen, Annette Sofie Davidsen, Klaus Martiny

“…Research is needed to bridge this gap, both regarding interventions for patients transitioning from secondary to primary care, and patients' and health care professionals' experiences of the interventions and of what promotes recovery.…”
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Application of the weighted histogram method for calculating the thermodynamic parameters of the formation of oligodeoxyribonucleotide duplexes by I. I. Yushin, V. M. Golyshev, D. V. Pyshnyi, A. A. Lomzov

“…These parameters can be calculated only for a few NA derivatives: locked NAs, bridged oligonucleotides, and peptide NAs. Existing predictive approaches are based on an analysis of experimental data and the consequent construction of predictive models. …”
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Knowledge translation in Aboriginal and Torres Strait Islander research contexts in Australia: scoping review protocol by Raymond Lovett, Makayla-May Brinckley, Sarah Bourke, Felecia Watkin Lui

“…Introduction Knowledge translation (KT) involves bridging the gaps between research knowledge and research application or practice, by sharing this knowledge with knowledge-users. …”
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A review of approaches to the integration of humanitarian and development aid: the case of drought management in the Horn of Africa by Tahira Shariff Mohamed, Todd Andrew Crane, Samuel Derbyshire, Guyo Roba

“…It also considers Community Managed Disaster Risk Reduction (CMDRR), a modality envisaged by many as a bridge for enhancing local ownership and thus sustainability of both kinds of intervention. …”
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Advances in tissue engineering of peripheral nerve and tissue innervation – a systematic review by Jayson Sueters, Rowan van Heiningen, Ralph de Vries, Zeliha Guler, Judith Huirne, Theo Smit

“…In this study, a systematic review was performed on tissue-engineered advancements for peripheral nerves and tissues, to aid future developments in bridging the gap toward the clinic by identifying high-potential solutions and unexplored areas. …”
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The mental health impact of COVID-19: the need for community interventions and collaboration for recovery by Nadarajah Rajeshkannan, Daya Somasundaram, Balachandran Kumarendran, Thirunavukarasu Kumanan, Ivan Dinesh Aloysius, Nalayini Sugirthan, Sivanantham Sasikumar, Nalayini Jegathesan

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Optimizing the selection of quantitative traits in plant breeding using simulation by Rafael Augusto Vieira, Ana Paula Oliveira Nogueira, Roberto Fritsche-Neto

“…Simulations use mathematical models to replicate biological conditions, bridging theory and practice by validating hypotheses early and optimizing genetic gain and resource use. …”
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Athletic identity and its relationship to moral values among physical education university students by L. M. Obeidat, H. I. Momani, T. T. Ammari, M. A. Rababah

“…The study recommends consolidating athletic identity among students through increasing sports participation and activities, strengthening academic courses that deal with sports culture and sports values, involving female students in sports activities to enhance the level of their athletic identity to bridge the gap in the level of athletic identity between them and male students.…”
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CIVILIZATIONAL AND INSTITUTIONAL ASPECTS OF NATIONAL SELF-IDENTIFICATION IN UKRAINE: PHILOSOPHICAL-ANTHROPOLOGICAL APPROACH by M. I. Boichenko, O. V. Yakovleva, V. V. Liakh

“…The authors found that the analysis of the cultural and anthropological principles of national self-identity reveals two main opposed concepts: the concept of "eastern" cultural and social self-identity of Ukraine, which correlates with the metaphor of the split between "East" and "West", and the concept of "western" projection of the European future of Ukraine, which correlates with the metaphor of the bridge between "East" and "West". These concepts reflect the options for the citizens of Ukraine to make a personal choice of the way in achieving social self-identity. …”
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From fragmented to integrated healthcare managing hypertension post-stroke: a qualitative study by Hala F. Azhari, Jonathan Hewitt, Martin O'Neill, Alexander Smith, Terence Quinn, Jesse Dawson

“…These findings emphasize the need for systemic reforms and targeted interventions to bridge gaps in hypertension care delivery post-stroke.…”
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