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Cannabis, Endocannabinoids and Brain Development: From Embryogenesis to Adolescence
Published 2024-11-01Subjects: Get full text
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Widespread splicing changes in human brain development and aging
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Impact of ATF6 deletion on the embryonic brain development
Published 2025-06-01“…Summary: Although the unfolded protein response (UPR) is activated during brain development, its roles remain unclear. Here, we report that deletion of activating transcription factor 6 (ATF6), consisting of ATF6α and ATF6β, in the developing brain caused microcephaly and neonatal death in mice. …”
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Role of iron in brain development, aging, and neurodegenerative diseases
Published 2025-12-01Subjects: Get full text
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The role of nutrition and gut microbiome in childhood brain development and behavior
Published 2025-06-01Subjects: “…brain development…”
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Transcriptomic sex differences in early human fetal brain development
Published 2025-04-01“…Taken together, our data suggest that limited but potentially important sex differences occur during early human fetal brain development.…”
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How early olfactory experiences influence brain development in mice
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Immunoglobulin superfamily 3 (Igsf3) function is dispensable for brain development
Published 2025-02-01“…Remaining unexplored is the physiological role of IGSF3 in regulating brain development, including neocortical development. We generated an Igsf3 knockout (KO) mouse using a CRISPR/Cas9-based approach and explored the function of Igsf3 in regulating cortical development. …”
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Brain Organoids: Studying Human Brain Development and Diseases in a Dish
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Systemic stimulation of TLR2 impairs neonatal mouse brain development.
Published 2011-05-01“…The aim of this study was to investigate the potential effect of a TLR2 agonist on neonatal brain development.<h4>Methodology/principal findings</h4>Mice were injected intraperitoneally (i.p.) once a day from postnatal day (PND) 3 to PND11 with endotoxin-free saline, a TLR2 agonist Pam(3)CSK(4) (5 mg/kg) or Lipopolysaccharide (LPS, 0.3 mg/kg). …”
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Zebrafish glial-vascular interactions progressively expand over the course of brain development
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Prenatal environmental exposures and brain development: studies with baboons and other nonhuman primates
Published 2025-08-01“…We further examine the impact of environmental insults on fetal brain development, including air pollution, infection, ionizing radiation, and exposure to toxicants, and highlight the ways in which these factors can disrupt brain development and neural circuitry, leading to long-term cognitive and behavioral deficits. …”
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LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules
Published 2013-01-01“…Here, we will review normal processes of brain development and neuronal migration, describe neuronal migration diseases, and will focus on the microtubule-associated functions of LIS1 and DCX, which participate in the regulation of neuronal migration and are involved in the human developmental brain disease, lissencephaly.…”
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Microglia in the aged brain develop a hypoactive molecular phenotype after surgery
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Co-methylation networks associated with cognition and structural brain development during adolescence
Published 2025-01-01Subjects: Get full text
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Weaving Invisible Threads: The Impact of Caregiver Trauma on Parenting and Child Brain Development
Published 2025-07-01Subjects: Get full text
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FOXR1 regulates stress response pathways and is necessary for proper brain development.
Published 2021-11-01“…Further examination of newborn Foxr1 knockout brains revealed a decrease in cortical thickness and enlarged ventricles compared to littermate wild-type mice, suggesting that loss of Foxr1 leads to atypical brain development. Combined, these results suggest FOXR1 plays a role in cellular stress response pathways and is necessary for normal brain development.…”
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