Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances by Mithila Debnath, Mahir Azmal, Rashid Taqui, Moshiul Alam Mishu, Ajit Ghosh

“…Methods: A differential expression analysis was conducted using GEO2R, where the significant differentially expressed genes (DEGs) were identified in brain areas that include the Entorhinal Cortex (EC) and Posterior Cingulate (PC), as well as in peripheral blood. …”
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Is human-like decision making explainable? Towards an explainable artificial intelligence for autonomous vehicles by Jiming Xie, Yan Zhang, Yaqin Qin, Bijun Wang, Shuai Dong, Ke Li, Yulan Xia

“…Based on the parallelism in the complex neural network of human brain, we construct a Width Human-like neural network (WNN) model for personalized cognitive and human-like driving intention decision making. …”
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Effect of open and locked exercise on cognitive function in older adults by Yuping Zou

“…Results: Open sports can effectively improve attention, executive function and cognitive flexibility in the elderly, and closed sports can have positive effects on memory and concentration by enhancing brain neuroplasticity and regulating neurotransmitters. …”
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Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review by Xiao Wei Tan, Hasvinjit Kaur Gulwant Singh, Jovi Zheng Jie Koh, Rachel Si Yun Tan, Phern Chern Tor

“…Nonetheless, symptom-specific brain circuit targeting has not been tested prospectively. …”
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Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment by Haiyi Zhang, Lu Zhang, Juan Lu, Jiajun Yue, Zhengzhen Yuan, Jidan Hu, Qi Yao, Yuting Fu, Guiquan Chen, Jiliang Fang, Jie Zhao

“…The results of ICA revealed that patients diagnosed with BD-MCI exhibited abnormal connectivity patterns across 12 groups of independent components and 5 distinct groups of brain networks. In one group, the internal connectivity within the brain network exhibited abnormalities. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Additionally, we analyzed single-cell RNA-seq (scRNA-seq) data from AD patients’ brain tissue and peripheral blood, combined with scRNA-seq data from experimental autoimmune encephalomyelitis (EAE) mouse brain tissue. …”
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Humans rationally balance detailed and temporally abstract world models by Ari E. Kahn, Nathaniel D. Daw

“…Our work adds to a growing body of research showing that the brain arbitrates between approximate decision strategies. …”
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Neuronal oscillations and functional connectivity of paced nostril breathing: A high-density EEG study. by Anita B Frohlich, Flavio Frohlich, Miriam Sklerov

“…Controlling nostril airflow through hand manipulations is an ancient yoga technique that has been suggested to provide targeted modulation of neuronal excitability and regulation of autonomic function, which is known to be lateralized in the brain. Here, we examined if unilateral and alternate nostril breathing differentially impacts brain network oscillations measured by high-density EEG in healthy control participants with no prior experience in breathing techniques. …”
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Readiness for Perception and Action: Towards a More Mechanistic Understanding of Phasic Alertness by Christian H. Poth

“…Human survival requires prompt perception and action to address relevant events in the environment. For this, the brain has evolved a system that uses warning stimuli to elicit phasic alertness, a state readying the brain for upcoming perception and action. …”
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The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury by Yanina Tsenkina

“… Cerebrovascular injuries, such as stroke and other vascular insults to the brain, present significant challenges to neurological function and recovery. …”
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Multi-organ frailty is enhanced by periodontitis-induced inflammaging by Yoshitaka Kase, Satoru Morikawa, Yuji Okano, Tatsuya Hosoi, Takazumi Yasui, Yoko Taki-Miyashita, Mitsutaka Yakabe, Maraku Goto, Kazuyuki Ishihara, Sumito Ogawa, Taneaki Nakagawa, Hideyuki Okano

“…The organs assessed for frailty included the gastrocnemius muscle, soleus muscle, brain, and femur. Results Our study found that periodontitis induced systemic inflammation resembling inflammaging and other symptoms characteristic of age-induced frailty. …”
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Sciatic nerve analysis in thyroid hormone transporters Mct8 and Oatp1c1 knockout mice by Steffen Mayerl, Andrea Alcaide Martin, Reinhard Bauer, Heike Heuer

“…These abnormalities have been attributed to impaired TH transport across brain barriers and into neural cells, thereby affecting brain development and function. …”
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Cortical representation of novel tool use: Understanding the neural basis of mechanical problem solving by Clara Seifert, Thabea Kampe, Cilia Jäger, Jennifer Randerath, Afra Wohlschläger, Joachim Hermsdörfer

“…Discussion: During mechanical problem solving brain activation is more pronounced in the ventro-dorsal stream, where mechanical understanding and motor control need to be integrated. …”
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Optimization of cyber security through the implementation of AI technologies by Nawaf Liqaa, Bentotahewa Vibhushinie

“…The Metaheuristic algorithms are stimulated by the human brain, so implementing Artificial Intelligence (AI) that assists the Neural Network to mimic the behaviour of the human brain is important to predict significant outcomes. …”
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Irritable Bowel Syndrome in Terms of Changes in the Microbiota by Vladimir T. Ivashkin, Oxana Yu. Zolnikova

“…The term “microbiota — intestine — brain” clearly demonstrates the correlation between the main functional components of IBS. …”
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A case of post-traumatic anterior cranial dural arteriovenous fistula by Vishal Bhasme, Divya Jain, Lomesh Bhirud

“…Abstract Introduction Dural arteriovenous fistula (dAVF) is an abnormal connection between an artery supplying the brain and vein or a venous sinus draining it. They account 10–15% of total arteriovenous malformations and are mostly idiopathic. …”
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Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review by Ke Chen, Boyang Jiang, Boyang Jiang, Huiping Yan, Huiping Yan, Liu Yang, Liu Yang, Zheling Chen, Zheling Chen

“…In addition, more and more studies have emphasized the efficacy and safety of bevacizumab in the treatment of brain metastases from solid tumors. Bevacizumab has its advantages in terms of crossing the blood-brain barrier, increasing radiosensitivity, and reducing radiation-induced brain edema. …”
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Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section by Mathieu Di Miceli, Moïra Rossitto, Maud Martinat, Flore Marchaland, Sarah Kharbouche, Marion Graland, Farah Younes, Alexandra Séré, Agnès Aubert, Lydia Rabbaa Khabbaz, Charlotte Madore, Jean-Christophe Delpech, Rebeca Martín, Sophie Layé

“…Altogether, our study shows altered emotional behaviour in animals delivered by CSD, which is likely explained by underlying neuro-inflammatory processes in different brain regions. Our work further supports the long-term consequences of CSD on brain health.…”
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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model by Sanghee Lim, Minhye Kwak, Jeonghan Kang, Melissa Cesaire, Kayen Tang, Robert W. Robey, William J. E. Frye, Baktiar Karim, Donna Butcher, Martin J. Lizak, Mahalia Dalmage, Brandon Foster, Nicholas Nuechterlein, Charles Eberhart, Patrick J. Cimino, Michael M. Gottesman, Sadhana Jackson

“…We found that ibrutinib, in a dose-dependent manner, decreased brain endothelial cell–cell adhesion over 24 h, without affecting endothelial cell viability (p < 0.005). …”
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The edge of chaos is that where consciousness manifests itself through intermittent dynamics by Valeriy Sbitnev

“…At such temperatures, only heavy ions, such as hydrogen ions (protons), can pass robustly through the water medium of the brain. Robust ion transport involves proton water wires supported by the Grotthuss mechanism. …”
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