Diverse Profiles of Toll-Like Receptors 2, 4, 7, and 9 mRNA in Peripheral Blood and Biopsy Specimens of Patients with Celiac Disease by Haniye Ghasiyari, Mohammad Rostami-Nejad, Davar Amani, Kamran Rostami, Mohamad Amin Pourhoseingholi, Hamid Asadzadeh-Aghdaei, Mohammad Reza Zali

“…Upregulation of TLR4 and TLR9 suggests the contribution of gut microbiota or dysregulation of the immune response to commensal flora in small bowel mucosa in celiac patients.…”
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Diagnostics and treatment of chronic constipation in adults: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, A. S. Trukhmanov, Ye. A. Poluektova, Ye. K. Baranskaya, O. S. Shifrin, T. L. Lapina, M. F. Osipenko, V. I. Simanenkov, I. B. Khlynov

“…Two types of constipation are usually distinguished: primary (functional) and secondary that is related to mechanical obstruction of the intestinal passage of bowel content, neurologic and endocrine diseases, systemic diseases of connective tissue, intake of drugs etc. …”
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Impact of Immunotherapies on SARS-CoV-2-Infections and Other Respiratory Tract Infections during the COVID-19 Winter Season in IBD Patients by Constanze Heike Waggershauser, Cornelia Tillack-Schreiber, Paul Weyh, Eckard Alt, Thorsten Siegmund, Christine Berchthold-Benchieb, Daniel Szokodi, Fabian Schnitzler, Thomas Ochsenkühn

“…This study is focused on the question whether patients with inflammatory bowel disease (IBD) who receive immunotherapies are more vulnerable to respiratory tract infections and SARS-CoV-2 infections in comparison to medical staff, as a cohort with an increased infection risk, and to the general population in a COVID-19 hotspot. …”
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Oral nutritional supplements for gastric cancer – the review of current evidence by A. L. Potapov, V. E. Khoronenko, E. V. Gameeva, Zh. V. Khailova, A. D. Dorozhkin, V. Yu. Scoropad

“…After gastrectomy (GE) its administration reduces the time of recovery of bowel motor function and the duration of hospitalization. …”
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MiMeJF: Application of Coupled Matrix and Tensor Factorization (CMTF) for Enhanced Microbiome-Metabolome Multi-Omic Analysis by Zheyuan Ou, Xi Fu, Dan Norbäck, Ruqin Lin, Jikai Wen, Yu Sun

“…Validation was conducted using three diverse microbiome/metabolome datasets, including built environments and human gut samples from inflammatory bowel disease (IBD) and COVID-19 studies. <b>Results</b>: Our results revealed biologically meaningful biomarkers, such as <i>Bacteroides vulgatus</i> and acylcarnitines associated with IBD and pyroglutamic acid and p-cresol associated with COVID-19 outcomes, which provide new avenues for research. …”
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Characteristics of Pediatric Crohn’s Disease in Saudi Children: A Multicenter National Study by Omar I. Saadah, Mohammad El Mouzan, Mohammad Al Mofarreh, Ali Al Mehaidib, Mohammad Al Edreesi, Mohammed Hasosah, Abdulrahman Al-Hussaini, Khalid AlSaleem

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Association between long-term exposure to air pollution and immune-mediated diseases: a population-based cohort study by Giovanni Adami, Angelo Fassio, Giovanni Orsolini, Davide Gatti, Maurizio Rossini, Ombretta Viapiana, Camilla Benini, Elena Fracassi, Giorgio Cattani, Marco Pontalti, Eugenia Bertoldo

“…Exposure to PM10 was associated with an increased risk of rheumatoid arthritis; exposure to PM2.5 was associated with an increased risk of rheumatoid arthritis, connective tissue diseases (CTDs) and inflammatory bowel diseases (IBD).Conclusion Long-term exposure to air pollution was associated with higher risk of developing autoimmune diseases, in particular rheumatoid arthritis, CTDs and IBD. …”
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The gut microbiota predicts and time-restricted feeding delays experimental colitis by Hannah K. Ruple, Eva Haasis, Anna Bettenburg, Carina Maier, Carolin Fritz, Laura Schüle, Sarah Löcker, Yvonne Soltow, Lynn Schintgen, Nina S. Schmidt, Celine Schneider, Axel Lorentz, W. Florian Fricke

“…The etiology of inflammatory bowel disease (IBD) remains unclear, treatment options unsatisfactory and disease development difficult to predict for individual patients. …”
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Impact of “Enhanced Recovery After Surgery” (ERAS) protocols vs. traditional perioperative care on patient outcomes after colorectal surgery: a systematic review by Vaishnavi Kannan, Najeeb Ullah, Sunitha Geddada, Amir Ibrahiam, Zahraa Munaf Shakir Al-Qassab, Osman Ahmed, Iana Malasevskaia

“…ERAS patients also had faster gastrointestinal recovery, including quicker times to bowel movement, defecation, and resumption of normal diet. …”
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Children’s and Their Parents’ Experiences With Home-Based Guided Hypnotherapy: Qualitative Study by Ilse N Ganzevoort, Adriëlla L van der Veen, Manna A Alma, Marjolein Y Berger, Gea A Holtman

“… Abstract BackgroundManagement of children with functional abdominal pain (FAP) or irritable bowel syndrome (IBS) is difficult in primary care. …”
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Assessment of the Utility of Selected Inflammatory Markers in Correlation with Magnetic Resonance Enterography (MRE) Findings in the Diagnosis of Crohn’s Disease by Justyna Lorenc-Góra, Dariusz Waniczek, Zenon P. Czuba, Mariusz Kryj, Zbigniew Lorenc, Małgorzata Muc-Wierzgoń

“…Crohn’s Disease (CD) is a chronic inflammatory bowel disease affecting the gastrointestinal tract. …”
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Sigmoid Volvulus in Pregnancy Assessed by Contrast-Enhanced Computed Tomography Scanning by Toshiaki Watanabe, Tadatsugu Kinjo, Yoshino Kinjyo, Hayase Nitta, Hitoshi Masamoto, Keiko Mekaru, Yoichi Aoki

“…Ultrasonography revealed no placental thickening, and maternal bowel dilation was difficult to identify. Plain abdominal X-ray showed a dilated colon on the left side of the abdomen. …”
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Prevalence, Treatment, and Unmet Needs of Migraine in the Middle East: A Systematic Review by Taoufik Alsaadi, AbuBakar Al Madani, Mohammed Alhatou, Mona Nada, Abdulrazaq Albilali, Ahmed Al-Qassabi, Hegab Mohamed, Haytham Mohamed, Rowan El Masry, Ghaidaa Ahmed Saifuddin, Suhail Abdullah AlRukn

“…Common comorbidities reported were depression, anxiety, and irritable bowel disease. Migraines significantly impact patients' physical and emotional well-being, leading to disabilities and loss of productivity. …”
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Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol by Juil Kim, BoGyoung Song, Ki-Hyung Kim, Yuseok Moon

“…DON exposure disrupts ribosomal function, inducing stress responses linked to various inflammatory diseases, including inflammatory bowel disease (IBD). In this study, we elucidate a novel regulatory mechanism involving ribosomal proteins (RPs) RPL13A and RPS3, which mediate proinflammatory chemokine production in DON-exposed gut epithelial cells. …”
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Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release by Shengnan Zhao, Zizhen Gong, Xixi Du, Chunyan Tian, Lingyu Wang, Jiefei Zhou, Congfeng Xu, Yingwei Chen, Wei Cai, Jin Wu

“…We recently have proved that excessive fecal DCA caused by high-fat diet may serve as an endogenous danger-associated molecular pattern to activate NLRP3 inflammasome and thus contributes to the development of inflammatory bowel disease (IBD). Moreover, the effect of DCA on inflammasome activation is mainly mediated through bile acid receptor sphingosine-1-phosphate receptor 2 (S1PR2); however, the intermediate process remains unclear. …”
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Prominence of Microbiota to Predict Fibrous Stenosis in Crohn&rsquo;s Disease by Yang X, Pan Y, Gao CP, Li H, Zhang YH, Huang CL, Cao L, Xiao SY, Zhou Z

“…Although several clinical risk factors for fibrous stenosis have been identified, such as perianal fistulizing disease, small bowel disease location, and deep mucosal ulceration, predicting fibrous stenosis remains challenging. …”
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TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease by Menghao Zhang, Na Kang, Xin Yu, Xiaoyang Zhang, Qinghui Duan, Xianqiang Ma, Qiancheng Zhao, Zhimian Wang, Xiao’ou Wang, Yeling Liu, Yuxiao Zhang, Can Zhu, Ruiyu Gao, Xin Min, Cuifeng Li, Jin Jin, Qian Cao, Rongbei Liu, Xiaoyin Bai, Hong Yang, Lidan Zhao, Jinjing Liu, Hua Chen, Yonghui Zhang, Wanli Liu, Wenjie Zheng

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Clinical case of a pelvic fracture with massive retroperitoneal hematoma by D.A. Krishtafor, A.A. Krishtafor, A.V. Tsarev, D.V. Balyk, A.Y. Halushchak, V.A. Pelekh

“…At the emergency laparotomy, a hematoma was found, which spread through the retroperitoneal space to the level of the diaphragmatic crura and the root of the small-bowel mesentery in a relatively thin layer, which explained the impossibility of its visualization by ultrasound or CT. …”
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Combined negative pressure wound therapy with new wound dressings to repair a ruptured giant omphalocele in a neonate: a case report and literature review by Shulin Hou, Zeyao Shi, Xiaowen Li, Ru Yang, Yan Song, Zhaolan Zeng

“…The herniation of the bowel was gradually reduced into the abdominal cavity. …”
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Usefulness of Routine Terminal Ileoscopy and Biopsy during Colonoscopy in a Tropical Setting: A Retrospective Record-Based Study by Hasitha Srimal Wijewantha, Arjuna Priyadarsin de Silva, Madunil Anuk Niriella, Nethini Wijesinghe, Prabahvi Waraketiya, Ravindu Sujeewa Kumarasena, Anuradha Supun Dassanayake, Janaki de Silva Hewawisenthi, Hithanadura Janaka de Silva

“…Patients with right iliac fossa (RIF) pain, diarrhoea, anaemia, suspected inflammatory bowel disease (IBD), and raised inflammatory markers were defined as Group A and all others undergoing colonoscopy as Group B. …”
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