Perioperative complications following spinal fusion in idiopathic scoliosis: A review of 825 cases from the German Spine Registry (DWG-register) – Perioperative complications in id... by Juan Manuel Vinas-Rios, Vincent J. Heck, Fatima Azucena Medina-Govea, Mario Alberto Islas-Aguilar, Nikolaus Kernich

“…A 1.3% rate of major complications and 1.6% rate of minor complications were recorded as follows: spinal cord damage n = 2 (8.4%), subfaszial hematoma n = 2 (8.4%), motor dysfunction n = 1 (4.2%), cerebrospinal fluid (CSF)-leakage n = 7 (29.2%), sensory dysfunction n = 6 (25%), bowel/bladder dysfunction n = 1 (4.2%), superficial site infection n = 2 (8.4%), and pulmonary lung atelectasis n = 3 (12.5%). …”
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Mucosal Epithelial Jak Kinases in Health and Diseases by Narendra Kumar, Longxiang Kuang, Ryan Villa, Priyam Kumar, Jayshree Mishra

“…As information about the roles of Jak3 in gastrointestinal functions and associated diseases are only just emerging, in the review, we summarize its implications in gastrointestinal wound repair, inflammatory bowel disease, obesity-associated metabolic syndrome, and epithelial cancers. …”
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Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice by E. A. Litvinova, K. M. Achasova, M. A. Borisova, S. V. Zhenilo, E. B. Prokhortchouk, E. N. Kozhevnikova

“…The number of people with inflammatory bowel disease (IBD) is constantly increasing worldwide. …”
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Serum Cytokine Profiles in Children with Crohn’s Disease by Ekaterina Vasilyeva, Sayar Abdulkhakov, Georgi Cherepnev, Ekaterina Martynova, Irina Mayanskaya, Alina Valeeva, Rustam Abdulkhakov, Dilyara Safina, Svetlana Khaiboullina, Albert Rizvanov

“…Crohn’s disease (CD) is a chronic inflammatory bowel disease that can be diagnosed at any age. There are two major patient groups based on diagnosis of this disease, before or after the age of 20 (juvenile/adolescent or adult), with disease progression in adults usually milder than in juvenile CD patients. …”
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The prevalence of hypermobile Ehlers–Danlos syndrome at a gender-affirming primary care clinic by Theo Stein, Shannon Collins, Joshua St. Louis

“…Within the sample of patients with hypermobile Ehlers–Danlos syndrome, 81.4% were found to have diagnoses of anxiety, depression, or attention deficit hyperactivity disorder, 50.8% had a history of migraines or dysautonomia, 39.0% had a history of gastroesophageal reflux disease, irritable bowel syndrome, nausea, diarrhea, or gastroparesis, 16.9% had history of mast cell activation disorder, 32.2% had postural orthostatic tachycardia syndrome, 30.5% had dysmenorrhea, 83.1% reported chronic pain, and 44.1% reported chronic fatigue. …”
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Tumour necrosis factor inhibitors in Ulcerative colitis: real-world data on Therapeutic drug monitoring and evaluation of current treatment targets (STRIDE II) by Jonas Andre Lundekvam, Marte Lie Høivik, Karoline Anisdahl, Milada Cvancarova Småstuen, David J. Warren, Nils Bolstad, Asle Wilhelm Medhus

“…Background The benefit of therapeutic drug monitoring (TDM) and implementation of recommendations from the Selection of Therapeutic Targets in Inflammatory Bowel Disease (IBD, STRIDE) are discussed in the IBD community. …”
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Association of Tissue Transglutaminase Antibody Titer with Duodenal Histological Changes in Children with Celiac Disease by Hasan Hawamdeh, Basim Al-Zoubi, Yasameen Al Sharqi, Ayman Qasrawi, Yousef Abdelaziz, Maha Barbar

“…Celiac disease is usually diagnosed by demonstrating gluten enteropathy in small bowel biopsy. Celiac specific antibodies are used as an initial screening test. …”
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Safety and Efficacy of Exclusive Enteral Nutrition for Percutaneously Undrainable Abdominal Abscesses in Crohn’s Disease by Yibin Zhu, Liang Xu, Wei Liu, Weilin Qi, Qian Cao, Wei Zhou

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Pros and Cons of the SeHCAT Test in Bile Acid Diarrhea: A More Appropriate Use of an Old Nuclear Medicine Technique by Bernardo Fani, Lorenzo Bertani, Italia Paglianiti, Lorenzo Fantechi, Nicola De Bortoli, Francesco Costa, Duccio Volterrani, Santino Marchi, Massimo Bellini

“…Bile acid malabsorption (BAM) causing chronic diarrhea may be due to organic as well as functional disorders, and some of them were included under the general label of diarrheic-type irritable bowel syndrome (IBS-D). The 75-selenium homocholic acid taurine (SeHCAT) test is a nuclear medicine investigation considered to be the gold standard for the diagnosis of bile acid malabsorption (BAM). …”
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Mast Cells Exert Anti-Inflammatory Effects in an IL10−/− Model of Spontaneous Colitis by E. M. Lennon, L. B. Borst, L. L. Edwards, A. J. Moeser

“…Mast cells are well established as divergent modulators of inflammation and immunosuppression, but their role in inflammatory bowel disease (IBD) remains to be fully defined. …”
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Effect of behavioral stage change theory on postoperative rehabilitation and quality of life in male patients with primary hepatocellular carcinoma resection: a retrospective study by Lili Dong, Fanfan Zhang

“…After nursing intervention, in the observation group, the time to get out of bed, bowel sound recovery time, first exhaustion time and first defecation time were significantly shorter compared to the control group (p < 0.05). …”
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Plasma Citrulline in the Diagnosis and Follow-Up of Celiac Disease by Alicia Isabel Pascual Pérez, Elene Larrea Tamayo, Santiago Jiménez Treviño, David González Jiménez, David Pérez Solís, Cristina Molinos Norniella, Juan José Díaz Martín

“…Background/Objectives: Citrulline, an amino acid produced by small bowel enterocytes, has been proposed as a potential marker of intestinal absorptive capacity. …”
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Factors Predicting the Adherence to the Therapy of Italian IBD Patients by Cristina Bucci, Fabiana Zingone, Stella Tammaro, Paola Iovino, Antonella Santonicola, Carolina Ciacci

“…Background. Inflammatory bowel diseases (IBD) are chronic gastrointestinal disorders influencing many aspects of the patient’s life and accounting for substantial social costs. …”
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Tubular Duplication of the Midgut Presenting with Acute Abdomen and Hematochezia: A Case Report from Northern Tanzania by Ayesiga M. Herman, David Msuya, Mwemezi Kaino, Hilary Shilanaiman, Joachim Magoma, Christian Issangya, Jay Lodhia, Murad Tarmohamed, Jeremia Pyuza, Patric Amsi, Alex Mremi, Ronald Mbwasi, Nuru Letara

“…Furthermore, the management options including total resection, mucosal striping, and internal drainage of the duplicate depend on the presentation of the patient, site, and length of the involved bowel. We present the first documented case of enteric duplication in Tanzania, a 3-year-old male, who was found to have a 90 cm long jejunoileal duplicate. …”
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Prognostic Factors of Peritoneal Metastases from Colorectal Cancer following Cytoreductive Surgery and Perioperative Chemotherapy by Yutaka Yonemura, Emel Canbay, Haruaki Ishibashi

“…Regarding the PCI of small bowel (SB-PCI), 89 of 94 (91.5%) patients with ≤2 and 22 of 48 (45.8%) patients with SB-PCI ≥ 3 received CCR-0 resection (P<0.001). …”
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Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate by Halyna M. Kuznietsova, Maryna S. Yena, Iryna P. Kotlyar, Olexandr V. Ogloblya, Volodymyr K. Rybalchenko

“…The anti-inflammatory effects of MI-1 (2.7 mg/kg daily) compared to reference drug Prednisolone (0.7 mg/kg daily) after 14-day usage were evaluated on macro- and light microscopy levels and expressed in 21-grade scale. Redox status of bowel mucosa was also estimated. It was shown that in UC group the grade of total injury (GTI) was equal to 9.6 (GTIcontrol=0). …”
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Not “Much Room” in the Heart: A Rare Case of a Massive Intracardiac Candida Mass by Ali Haider Jafry, Sardar Hassan Ijaz, Murtaza Mazhar, Areeba Shahnawaz, Ali Yousif

“…A 51-year-old male on chronic total parenteral nutrition (TPN) because of bowel resection presented with fevers, night sweats, and unintentional weight loss. …”
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IL-33 Aggravates DSS-Induced Acute Colitis in Mouse Colon Lamina Propria by Enhancing Th2 Cell Responses by Junfeng Zhu, Fangli Yang, Lixuan Sang, Jingbo Zhai, Xiaoqing Zhang, Dan Yue, Shengjun Li, Yan Li, Changlong Lu, Xun Sun

“…It suggested that IL-33 plays a potential role in inflammatory bowel diseases (IBD). We investigated the role of interleukin- (IL-) 33 in dextran sulphate sodium- (DSS-) induced acute colitis in mice using recombinant mouse IL-33 protein (rIL-33). …”
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SMAD4 Protein Expression Is Downregulated in Ileal Epithelial Cells from Patients with Crohn’s Disease with Significant Inverse Correlation to Disease Activity by Pia Klausen, John Gásdal Karstensen, Mehmet Coskun, Adrian Săftoiu, Peter Vilmann, Jack Bernard Cowland, Lene Buhl Riis

“…Small mothers against decapentaplegic (SMAD)4 and SMAD7 are key regulatory components in the immunosuppressive transforming growth factor- (TGF-) β signaling pathway, which is defective in inflammatory bowel disease (IBD). SMAD4 may play an important role in the pathogenesis of IBD as indicated in experimental models of colitis. …”
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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres by David Young, Sohail Rahmany, Deborah Taylor, Emma Davis, Michael Colwill, Sonia Kalyanji Mehta, Roisin Campbell, Karl Hazel, Karishma Sethi-Arora, Susan Ritchie, Ashley I Heinson, Helen Moyses, Keith Bodger, Emma Johnston, Lucy Hicks, Anjan Dhar, Jimmy Limdi, Rachel Cooney, John Paul Seenan, Kamal Patel, Alissa Walsh, Fraser Cummings

“…Methods: A retrospective observational cohort evaluation was conducted across nine UK inflammatory bowel disease centres. Baseline demographic and clinical data, clinical disease activity scores, endoscopic activity indices, and biomarkers (C-reactive protein and faecal calprotectin) were collected at baseline, at 8–12 weeks after initiation (post-induction) and during maintenance (the most recent review) where available. …”
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