Healthy Living: Staying Regular by Linda B. Bobroff, Luisa Oliver-Cordero

“…Having a bowel movement fewer than three times a week is defined as constipation. …”
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Frequency of Functional Constipation in Lebanese Children: A Cross-Sectional Study Based on Parental Reporting by Theresia Tannoury, Jana Assy, Nadine Yazbeck

“…Conclusion: The present study shows that 32.6% of children aged 2–7 years in Lebanon suffer from constipation while only 51.7% of the recruited children’s physicians inquire about the child’s bowel movement during the well check visit. These numbers highlight the need to raise more awareness among pediatricians on the need to screen for constipation during clinic visits as a standard of care practice.…”
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Prevalence and predictors of severe Crohn’s disease at a tertiary hospital in South Africa by C Gounden, V Naidoo, Y Moodley

“…Demographic and clinical variables at diagnosis of CD were collected and analysed for statistical association with development of SCD (defined as the presence of >/= 1 of the following over the course of CD: complex perianal disease, colonic resection >/= 2 small bowel resections, a single small bowel resection > 50cm, or construction of a definitive stoma). …”
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Cauda Equina Syndrome Without Perineal Sensory Changes or Lower Extremity Neurological Deficits Following Postoperative Spinal Epidural Hematoma: A Case Report and Literature Revie... by Guanyi Liu, Qing Li, Hongfeng Ruan, Bingke Zhu, Weihu Ma, Yong Hu

“…Despite the delayed intervention, the patient made a full neurological recovery, with bladder and bowel functions restored by 3 months postoperatively. …”
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Perioperative Management of a Patient with Hereditary Angioedema and Intestinal Obstruction Secondary to an Ileal Tumor: A Case Report by Antony Peter Gatheru, Anne Kasyoka Barasa, Isaac Karogo Mwangi, Stanley Ngare, Dan Kiptoon, Edwin Oloo Walong

“…We describe the successful management of a 41-year-old female with HAE presenting with features of intestinal obstruction, which only partially resolved with the administration of C1-INH and conservative bowel decompressive management. Imaging revealed a small bowel tumor necessitating surgical intervention. …”
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Influence of Enhanced Recovery Pathway on Surgical Site Infection after Colonic Surgery by Caroline Gronnier, Fabian Grass, Christiane Petignat, Basile Pache, Dieter Hahnloser, Giorgio Zanetti, Nicolas Demartines, Martin Hübner

“…Smoking, open and emergency surgery, and bowel preparation were risk factors for SSI. ERAS pathway had no independent impact while minimally invasive approach did. …”
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Hartmann’s Procedure Versus Intersphincteric Abdominoperineal Excision in Patients with Rectal Cancer: Report from the Swedish Colorectal Cancer Registry (SCRCR) by Viktor Åkerlund, MD, Maziar Nikberg, MD, PhD, Philippe Wagner, PhD, Abbas Chabok, MD, PhD

“…The mean operating time was less for HP (290 vs 377 min). Intraoperative bowel perforations were less frequent in the HP group, 3.6% versus 10.2%. …”
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Vaginal Treatment of Vaginal Cuff Dehiscence with Visceral Loop Prolapse: A New Challenge in Reparative Vaginal Surgery? by Salvatore Andrea Mastrolia, Edoardo Di Naro, Luca Maria Schonauer, Maria Teresa Loverro, Beatrice Indellicati, Mario Barnaba, Giuseppe Loverro

“…After dehiscence of the vaginal cuff, abdominal or pelvic contents may prolapse through the vaginal opening. Bowel evisceration, outside the vulvar introitus, can lead to serious sequelae, including peritonitis, bowel injury and necrosis, or sepsis. …”
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Advancing Therapeutic Targets in IBD: Emerging Goals and Precision Medicine Approaches by Lucia Centanni, Clelia Cicerone, Fabrizio Fanizzi, Ferdinando D’Amico, Federica Furfaro, Alessandra Zilli, Tommaso Lorenzo Parigi, Laurent Peyrin-Biroulet, Silvio Danese, Mariangela Allocca

“…Inflammatory bowel diseases (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, relapsing conditions characterized by dysregulated immune responses and persistent intestinal inflammation. …”
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Nonoperative management of colon and mesocolon injuries caused by blunt trauma: three case reports by Naa Lee, Euisung Jeong, Hyunseok Jang, Yunchul Park, Younggoun Jo, Jungchul Kim

“…Surgical treatment is often required if prominent mesenteric extravasation, free fluid, bowel infarction, and/or colon wall perforation are observed. …”
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Complimentary Imaging Modalities for Investigating Obscure Gastrointestinal Bleeding: Capsule Endoscopy, Double-Balloon Enteroscopy, and Computed Tomographic Enterography by Ye Chu, Sheng Wu, Yuting Qian, Qi Wang, Juanjuan Li, Yanping Tang, Tingting Bai, Lifu Wang

“…The diagnostic yield of angiodysplasia at CE was significantly higher than CTE (73% versus 8%, p<0.001) and DBE (39.1% versus 17.4%, p=0.013), while no significant difference was found between the three approaches for small bowel tumors. DBE and CTE identified small bowel diseases undetected or undetermined by CE. …”
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Risk of cancer in patients with bile acid diarrhoea: a Danish nationwide matched cohort study by Tine Jess, Nynne Nyboe Andersen, Gry Poulsen, Signe Wildt, Lars Kristian Munck, Aske Thorn Iversen, Christian Borup

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Variation in changes in the incidence of colorectal cancer by age and association with screening uptake: an observational study by Annie S Anderson, Callum G Fraser, Judith A Strachan, Robert JC Steele, Gavin RC Clark, Thomas G Godfrey

“…In addition, linkage between the Scottish Bowel Screening Database and the SCR allowed investigation of any association between screening participation and CRC incidence.Setting Scotland and the Scottish Bowel Screening Programme, in which guaiac faecal occult blood test screening was piloted from March 2000 and fully rolled by December 2009.Participants From the introduction of screening in 2000 through to 2017, 2 395 172 were invited to participate, of whom 1 487 999 participated at least once.Main outcome measures Incidence of CRC.Results In the screening age range (50–74 years), CRC incidence peaked at 156.5 cases per 100 000 in 2010 after full roll-out of screening across Scotland but fell to 123.9 per 100 000 in 2017. …”
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Spleno-Mesenteric Venous Blood Flow Dynamics in Adult Patients with Chronic Portal Vein Thrombosis Analyzed by Sequential CT-Spleno- and Mesenterico-Portography by Alexandra Schlitt, Andrea Goetz, Christian Stroszczynski, Florian Zeman, Christina Hackl, Hans J. Schlitt, Ernst-Michael Jung, Wibke Uller, Simone Hammer

“…In patients without PVCT, small bowel varices were fed by both systems or the SMV, while in patients with PVCT they were fed by the SMV (<i>p</i> = 0.031). …”
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Normalization of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation and Significantly Improves the Survival of Cystic Fibrosis MiceSummary by Callie E. Scull, Yawen Hu, Scott Jennings, Guoshun Wang

“…Activation of iNOS in inflammatory cells produces excessive NO, slows the bowel movement, and facilitates intestinal paralysis and obstruction in CF. …”
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Effectiveness, toxicity and impact on quality of life of high-dose-rate brachytherapy delivered in two fractions as monotherapy in patients with prostate cancer by Johan Staby Olsén, Antonis Valachis, Bengt Johansson

“…Conclusion: We found that two-fraction HDR-BT as monotherapy among patients with mainly low- and intermediate-risk prostate cancer appears to be safe in terms of biochemical recurrence, with a low proportion of severe urinary and bowel toxicity.…”
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The effect of ileostomy closure timing on low anterior resection syndrome in patient who underwent low anterior resection for rectal cancer by Hemn Hussain Kaka Ali, Qalandar Hussein Abdulkarim, Karzan Seerwan, Barham M. M .Salih, Omar H Ghalib Hawramy, Dara Ahmed Mohammed, Syamand Orhaman Ahmed

“…This study aimed to find the effect of temporary ileostomy on post-operative bowel defunction which is called Low anterior resection syndrome (LARS), and include; urgency, difficulty in emptying of bowel, and incontinence for feces and flatus.  …”
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Magnetic-Guided Capsule Endoscopy in the Diagnosis of Gastrointestinal Diseases in Minors by Yuting Qian, Tingting Bai, Juanjuan Li, Yi Zang, Tong Li, Mingping Xie, Qi Wang, Lifu Wang, Ruizhe Shen

“…The most common small bowel diseases in minors were Crohn’s disease, Henoch-Schonlein purpura, and polyps. …”
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Feasibility and complications of videocapsule endoscopy in dogs weighing 7 kg or less by Camille St‐Jean, Allison Collier, Alex Zur Linden, Alexa Bersenas, Alice Defarges

“…Its use is not recommended in dogs ≤4.3 kg, because of risks of GI endoscopic capsule (EC) retention and bowel obstruction. Objectives Describe the feasibility and complications of VCE in dogs ≤7 kg. …”
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Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF-κB Pathway Inhibition in Mice by Zhen Ni, Hao Li, Dong Mu, Juanni Hou, Xiaoyan Liu, Shanhong Tang, Shumei Zheng

“…The autophagy deficiency may affect the innate and adaptive immunity, which is related to persistent and excessive inflammation of the bowel. However, it remains unclear how autophagy modulates the expression of immune response regulator NF-κB and proinflammatory cytokine TNF-α in CD. …”
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