Cucurbitacin IIa Alleviates Colitis via Promoting the Release of Host-Derived Extracellular Vesicles Encapsulating microRNA-30b-5p by Zhao Y, Jiang B, Zuo S

“…In conclusion, cucurbitacin IIa appears to alleviate colitis by promoting the release of microRNA-30b-5p from host-derived extracellular vesicles.Conclusion: These findings enhance our understanding of cucurbitacin IIa’s effects on intestinal health and offer potential new therapeutic targets for inflammatory bowel disease treatment.Keywords: colitis, cucurbitacins, extracellular vesicles, inflammation, microRNA…”
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Unique quantitative electroencephalography differences and related behavioral dynamics in Crohn’s disease by Yihan Zhuang, Hairu Yang, Xinyi Huang, Guanghua Guo, Quan Shi, Yiting Lin, Wenwen Xue, Zeyu Huang, Sisi Zhou, Jiahui Cai, Haizhu Tan, Jing Yu

“…Crohn's disease (CD) is a major type of inflammatory bowel disease (IBD) characterized by idiopathic, chronic inflammation with a patchy transmural inflammatory pattern. …”
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The effect of cyclic rifaximin therapy on symptoms of diverticular disease from the perspective of the gastroenterology outpatient clinic: a “real-life” study by Andrzej Moniuszko, Grażyna Rydzewska

“…Results : After just one cycle of therapy a significant reduction in disease symptoms was observed (abdominal pain, abdominal tenderness, bloating, disturbances in bowel habit), defined over a scale of 0–3 points. …”
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The Impact of Intermediate Antidrug Antibodies to Infliximab and Adalimumab on Clinical Outcomes in Patients with Crohn’s Disease or Ulcerative Colitis by Chaoyang Wang, Mazen Tolaymat, Raymond Cross

“… Background: The anti-TNF drugs adalimumab (ADA) and infliximab (IFX) are effective treatments for inflammatory bowel disease (IBD). However, 40% of patients lose response, often due to the development of antibodies-to-ADA (ATA) and antibodies-to-IFX (ATI). …”
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Laparoscopy Combined with Enhanced Recovery Pathway in Ileocecal Resection for Crohn’s Disease: A Randomized Study by Yibin Zhu, Jianjian Xiang, Wei Liu, Qian Cao, Wei Zhou

“…A significantly earlier return of bowel function was observed in the ERAS group. Compared with the standard care group, patients in the ERAS group had shorter postoperative hospital stay and lower in-hospital costs (5.19 ± 1.28 versus 9.94 ± 3.33 days, P<0.001; 2.70 ± 0.50 versus 3.73 ± 0.75 ten thousand RMB, P<0.001, respectively). …”
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Assessing the rates of false-positive ovarian cancer screenings and surgical interventions associated with screening tools: a systematic review by Sierra M Silverwood, Grant Backer, Annie Galloway, Katrina Reid, Anna Jeter, Margo Harrison

“…Complications associated with unnecessary surgical interventions, such as perforation, blood loss and bowel injury, were only reported in four studies. …”
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New-onset gastrointestinal disorders in COVID-19 patients 3.5 years post-infection in the inner-city population in the Bronx by Sagar Changela, Samad Ashraf, Justin Y. Lu, Kevin E. Duong, Sonya Henry, Stephen H. Wang, Tim Q. Duong

“…The primary outcome was new GID which included peptic ulcer, inflammatory bowel disease, irritable bowel syndrome, diverticulosis, diverticulitis, and biliary disease. …”
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The first cases of collagenous sprue successfully treated with thioguanine by Chris J J Mulder, Gerd Bouma, Tom van Gils, Tine van de Donk, Foke van Delft, E Andra Neefjes-Borst

“…Objective Collagenous sprue (CS) is a rare form of small bowel enteropathy characterised by a thickened basement membrane and is, in most of the literature, reported as part of coeliac disease. …”
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Understanding the Impact of Urinary Incontinence in Persons with Dementia: Development of an Interdisciplinary Service Model by Patrick Juliebø-Jones, Elizabeth Coulthard, Elizabeth Mallam, Hilary Archer, Marcus J. Drake

“…Awareness of bladder and bowel services should be increased.…”
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Prevalence of Erosive-ulcerative Lesions of the Stomach and Helicobacter Pylori Infection in Patients with Ulcerative Colitis by N. A. Ponkratova, P. V. Pavlov, O. S. Shifrin

“…The study of H. pylori infection with RUT was carried out in 111 patients without inflammatory bowel disease, who formed the control group.Results. …”
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β-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC by Ernst Fredericks, Gill Dealtry, Saartjie Roux

“…Using qPCR and IHC, we compared β-catenin, PPARγ, COX-2, and IL-17A in the colonic mucosa of patients with sporadic CRC, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS), against a normal control population. …”
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Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies by Gong Wang, Mao Chen, Fei Gao, Meng Guo, Maohua Li, Qian He, Jiaojin Jiang, Cheng Huang, Xiaoyan Chen, Rui Xu

“…It was found that psychobehavioral abnormality (OR = 11.327, 95% CI: 1.371 to 93.602, P = 0.024), bowel and bladder dysfunction (OR = 23.537, 95% CI: 1.753 to 316.005, P = 0.017), and total protein of CSF (OR = 61.556, 95% CI: 2.926 to 1294.974, P = 0.008) were risk factors for increased number of high-risk antibodies in PNS. …”
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Diverticular Pylephlebitis and Polymicrobial Septicemia by Pradhum Ram, Kamolyut Lapumnuaypol, Chitra Punjabi

“…We report the first case of polymicrobial sepsis resulting from diverticular pylephlebitis, managed successfully with bowel rest, antibiotics, and anticoagulation.…”
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Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis? by Christopher N Andrews, Eldon A Shaffer

“…Not so long ago, physicians construed the irritable bowel syndrome (IBS) as being a neurotic trait: it was all in the head. …”
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Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trialResearch... by Katrine Lundby Høyer, Simon Mark Dahl Baunwall, Ditte Smed Kornum, Mette Winther Klinge, Asbjørn Mohr Drewes, Knud Bonnet Yderstræde, Louise Bruun Thingholm, Martin Steen Mortensen, Susan Mikkelsen, Christian Erikstrup, Christian Lodberg Hvas, Klaus Krogh

“…The Irritable Bowel Syndrome Impact Scale score improved from 108 (101–123) to 140 (124–161) with FMT and 77 (53–129) to 92 (54–142) with placebo (p = 0.02). …”
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Healthy Living: Staying Regular by Linda B. Bobroff, Luisa Oliver-Cordero

“…Having a bowel movement fewer than three times a week is defined as constipation. …”
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Tissue Staining (Chromoscopy) of the Gastrointestinal Tract by M Brian Fennerty

“…Some of the agents used for endoscopic tissue staining and the uses of chromoscopy in identifying pathology of the esophagus, stomach, small bowel and colon during endoscopy are discussed.…”
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Nonceliac Diaphragm Disease of the Duodenum by Hugh J Freeman

“…Other reported causes such as celiac disease and drug-induced small bowel diaphragms were excluded. Possibly, the changes seen in this patient were related to ethnic food-induced, mucosal injury to the upper gastrointestinal tract. …”
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Strangulated femoral Littre hernia in a 72-year-old female: A case report by Melanie B Mait, Samira M Hasan

“…In this report, we present a case of a femoral Littre hernia in a 72-year-old female repaired with femoral herniorrhaphy and laparoscopic-assisted small bowel resection.…”
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Ketotifen Treatment of Active Colitis in Patients with 5-Aminosalicylate Intolerance by John K Marshall, E Jan Irvine

“…Although the role of mucosal mast cells in the pathogenesis of inflammatory bowel disease remains uncertain, mast cell stabilizers have been shown in animal models to attenuate the severity of experimental colitis. …”
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