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    Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody by Bin Xie, Shipeng Xu, Sanjeevi Sivasankar

    Published 2025-01-01
    “…Here, we use a combination of biophysical, biochemical, and cell biological methods to demonstrate that trapping the P-cadherin extracellular region in an X-dimer adhesive conformation triggers cadherin endocytosis via an outside-in signaling mechanism. …”
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