Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived islets by Myungji Kim, Seungyeon Cho, Dong Gyu Hwang, In Kyong Shim, Song Cheol Kim, Jiwon Jang, Jinah Jang

“…However, stem cell (SC)-derived islets generated in vitro often lack the three-dimensional extracellular microenvironment and peri-vasculature, which leads to the immaturity of SC-derived islets, reducing their ability to detect glucose fluctuations and insulin release. Here, we bioengineer the in vivo-like pancreatic niches by optimizing the combination of pancreatic tissue-specific extracellular matrix and basement membrane proteins and utilizing bioprinting-based geometrical guidance to recreate the spatial pattern of islet peripheries. …”
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Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB) by Sesha Hanson-Drury, Sesha Hanson-Drury, Sesha Hanson-Drury, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Deborah L. Lee, Deborah L. Lee, Deborah L. Lee, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Yan Ting Zhao, Yan Ting Zhao, Yan Ting Zhao, Devon Duron Ehnes, Devon Duron Ehnes, Devon Duron Ehnes, Vivian N. Vo, Vivian N. Vo, Vivian N. Vo, Sydney Y. Kim, Sydney Y. Kim, Druthi Jithendra, Druthi Jithendra, Ashish Phal, Ashish Phal, Ashish Phal, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Thomas Schlichthaerle, Thomas Schlichthaerle, David Baker, David Baker, David Baker, Jessica E. Young, Jessica E. Young, Julie Mathieu, Julie Mathieu, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker

“…Clinicians, scientists, and the general public share the desire to regenerate this missing tooth structure. To bioengineer missing dentin, increased understanding of human tooth development is required. …”
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Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering by Marshall S. Padilla, Kaitlin Mrksich, Yiming Wang, Rebecca M. Haley, Jacqueline J. Li, Emily L. Han, Rakan El-Mayta, Emily H. Kim, Sofia Dias, Ningqiang Gong, Sridatta V. Teerdhala, Xuexiang Han, Vivek Chowdhary, Lulu Xue, Zain Siddiqui, Hannah M. Yamagata, Dongyoon Kim, Il-Chul Yoon, James M. Wilson, Ravi Radhakrishnan, Michael J. Mitchell

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Exploration of linear and interpretable models for quantification of cell parameters via contactless short-wave infrared hyperspectral sensing by Anjana Hevaganinge, Eva Lowenstein, Anna Filatova, Mihir Modak, Nandi Thales Mogo, Bryana Rowley, Jenny Yarmowsky, Joshua Ehizibolo, Ravidu Hevaganinge, Amy Musser, Abbey Kim, Anthony Neri, Jessica Conway, Yiding Yuan, Maurizio Cattaneo, Sui Seng Tee, Yang Tao

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From Blood to Therapy: The Revolutionary Application of Platelets in Cancer-Targeted Drug Delivery by Lijuan Xie, Fengxu Gan, Yun Hu, Yibin Zheng, Junshan Lan, Yuting Liu, Xiaofang Zhou, Jianyu Zheng, Xing Zhou, Jie Lou

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Advancements in Breathomics: Special Focus on Electrochemical Sensing and AI for Chronic Disease Diagnosis and Monitoring by Nikini Rashmithara Subawickrama Mallika Widanaarachchige, Anirban Paul, Ivneet Kaur Banga, Ashlesha Bhide, Sriram Muthukumar, Shalini Prasad

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Foreword by E Murer, P Niederer, B Radanov, A Rumo-Jungo, M Sturzenegger, F Walz

“…In recent years, whiplash has become a nightmare for doctors, lawyers, rehabilitation specialists, bioengineers and insurers, not only in Switzerland, but across the whole of western Europe, North America and Australia.…”
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Synthesis of Novel Thiazolyl Hydrazine Derivatives and Their Antifungal Activity by Jianjun Zhu, Yazhen Chen, Fen Su, Peiyi Wang

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The Effect of Cysteine on the Removal of Cadmium in Paddy Soil by Combination with Bioremediation and the Response of the Soil Microbial Community by Emmanuel Konadu Sarkodie, Kewei Li, Ziwen Guo, Jiejie Yang, Yan Deng, Jiaxin Shi, Yulong Peng, Yuli Jiang, Huidan Jiang, Hongwei Liu, Yili Liang, Huaqun Yin, Xueduan Liu, Luhua Jiang

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Generation of Femtosecond Laser-Cut Decellularized Corneal Lenticule Using Hypotonic Trypsin-EDTA Solution for Corneal Tissue Engineering by Man-Il Huh, Kyoung-Pil Lee, Jeongho Kim, Soojin Yi, Byeong-Ung Park, Hong Kyun Kim

“…Furthermore, it is possible to create a scaffold using a bioengineered corneal substitute.…”
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Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System by Roberto Reif, Jia Qin, Lin An, Zhongwei Zhi, Suzan Dziennis, Ruikang Wang

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Purification and Characterization of Bioactive Compounds from Styela clava by Bao Ju, Bin Chen, Xingrong Zhang, Chunling Han, Aili Jiang

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The rise of non-typhoidal Salmonella: an emerging global public health concern by Gaurav Kumar, Sandeep Kumar, Himanshu Jangid, Joydeep Dutta, Amrullah Shidiki

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Review on mechanisms and structure-activity relationship of hypoglycemic effects of polysaccharides from natural resources by Xiaolong Ji, Jianhang Guo, Tengzheng Cao, Tingting Zhang, Yanqi Liu, Yizhe Yan

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Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing by Alice Perucca, Andrea Gómez Llonín, Oriol Mañé Benach, Clement Hallopeau, Elisa I. Rivas, Jenniffer Linares, Marta Garrido, Anna Sallent-Aragay, Tom Golde, Julien Colombelli, Eleni Dalaka, Judith Linacero, Marina Cazorla, Teresa Galan, Jordi Pastor Viel, Xavier Badenas, Alba Recort-Bascuas, Laura Comerma, Patricia Fernandez-Nogueira, Ana Rovira, Pere Roca-Cusachs, Joan Albanell, Xavier Trepat, Alexandre Calon, Anna Labernadie

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Parameter space exploration within dynamic simulations of signaling networks by Cristina De Ambrosi, Annalisa Barla, Lorenzo Tortolina, Nicoletta Castagnino, Raffaele Pesenti, Alessandro Verri, Alberto Ballestrero, Franco Patrone, Silvio Parodi

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Research on Pork Jerky Obtained Through Fermentation with Pediococcus acidilactici by Zhao Xingxiu, Zhang Jing, Ming Hongmei, Zou Wei, Wang Yang, Zhao Changqing, Mu Shengdong, Zhang Hao, Qiu Lin

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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

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Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus by Li Qianqian, Shi Li, Liu Yingying, Guan Shimin, Zhang Shuo, Cai Baoguo, Rong Shaofeng

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Development of a sustainable route for the production of high‐fructose syrup from the polyfructan inulin by Kongkona Saikia, Hridya Radhakrishnan, Abiram Karanam Rathankumar, Siva Gokul Senthil Kumar, Shravani Kalita, Jenet George, Sivanesan Subramanian, Vaidyanathan Vinoth Kumar

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