Approved antibacterial drugs in the last 10 years: from the bench to the clinic by Miguel García-Castro, Francisco Sarabia, Amelia Díaz-Morilla, Juan Manuel López-Romero

“…Bacterial infections constitute one of the major cases of primary medical incidences worldwide. …”
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Do Infections Cause Oligospermia and Could Empiric Antibiotics Antiprotozoal and Antifungal Treat Oligospermia? by Mohammed Nabil Dajanı

“…Our aim is to study the effect of fungal, trichomonal and bacterial infections as causes of oligospermia and to find possible treatment for it. …”
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Linezolid and serotonin syndrome by Haytham A. Wali

“…Linezolid, a synthetic oxazolidinone antibiotic, is used to treat gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus . …”
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Phages as potential life-saving therapeutic option in the treatment of multidrug-resistant urinary tract infections by Beata Zalewska-Piątek, Michalina Nagórka

“…Urinary tract infections (UTIs) are among the most common bacterial infections worldwide and increasing antimicrobial resistance (AMR) challenges conventional antibiotic treatments. …”
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Recent advances in nanomaterials and their mechanisms for infected wounds management by Jianping Zhu, Fan Xia, Shuaifei Wang, Yan Guan, Fuqiang Hu, Fangying Yu

“…Nanomaterials have emerged as a promising solution for tackling bacterial infections and facilitating wound healing, thanks to their distinct physicochemical characteristics and multifunctional capabilities. …”
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Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model by Wei Li, Xue Wang, Keyuan Chen, Yaohong Zhu, Guiyan Yang, Yipeng Jin, Jiufeng Wang

“…Infantis-induced intestinal inflammation, suggesting that oral delivery of B. subtilis WB600/ZD may be a promising prophylactic strategy for combating bacterial infections in the intestine.…”
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Infected burn wound healing using Hydroxy-propyl-methyl cellulose gel containing bacteriophages against Pseudomonas aeruginosa and Klebsiella pneumoniae by Meysam Adibi, Kazem Javanmardi, Noor Al-Huda Ali A.H. Saeed, Mohammad Ali Mobasher, Javad Jokar, Abdolmajid Ghasemian, Niloofar Rahimian, Ava Soltani Hekmat

“…All of these actions were performed in separate groups for each bacteria and mixed group of bacteria (to test multi-bacterial infections treating) and the result were compared. …”
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Progress in the Study of Polymyxin Heteroresistance Molecular Mechanisms by LI Yanbing, ZHOU Menglan, XU Yingchun

“…Polymyxins, a class of cyclic peptide antibiotics, have become the last line of defense against gram-negative bacterial infections as the number of multidrug-resistant bacteria continues to rise. …”
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Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections by Yan T, Wang Q, Ma C, Teng X, Gong Z, Chu W, Zhou Q, Liu Z

“…This study aimed to evaluate the efficacy of phage therapy in treating bacterial infections.Methods: Isolated phage vB_Kpn_HF0522 and phage morphology were observed using transmission electron microscopy. …”
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Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases by Erica Casey Anders, Stanley Miller

“…Streptococcus intermedius, a gram-positive, beta-hemolytic, catalase-negative member of the Streptococcus milleri group, is a commensal organism within the human body that is known for its propensity to cause severe bacterial infections. This case report presents two distinct cases involving culture-positive S. intermedius infections. …”
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NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication by Hyeonseo Park, Tejal V. Patil, Jieun Lee, Hojin Kim, Seong-Jun Cho, Ki-Taek Lim

“…Abstract The rise of antibiotic resistance has made bacterial infections a persistent global health issue. In particular, extracellular polymeric substances (EPS) secreted by bacteria limit the effectiveness of conventional antibiotics, making biofilm removal challenging. …”
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Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

“…From a human health perspective, these data suggest that temperate phages may facilitate bacterial infections rather than function as protective agents. …”
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Defining and measuring suspicion of sepsis: an analysis of routine data by Charles Vincent, Bethan Page, Matthew Inada-Kim, Imran Maqsood

“…The SOS coding set consists of all bacterial infective diagnoses.Results We identified 47 475 admissions with SOS, equivalent to a rate of 17 admissions per 1000 adults in a given year. …”
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Dual-functional silver nanoparticle-enhanced ZnO nanorods for improved reactive oxygen species generation and cancer treatment by Yichao Tao, Wenbin Zhuang, Wensi Fan, Longxiang Zhou, Lihong Fan, Huanlong Qin, Yefei Zhu

“…Furthermore, the ZnO@Ag NRs’ antibacterial properties were also confirmed, suggesting additional benefits in treating cancers associated with bacterial infections. Collectively, these findings establish ZnO@Ag NRs as a potent and safe agent for ultrasound-driven cancer therapy.…”
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In vitro investigations of coelomic fluid of Eisenia fetida: protein analysis, antioxidant activities and antibacterial effects on diabetic wounds' bacteria by Negar Danafar, Marzieh Shokoohi

“…Diabetic wounds are prone to bacterial infections, with common pathogens including Staphylococcus, Escherichia coli, Bacillus subtilis and Pseudomonas aeruginosa. …”
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Nanozyme based ultra-stretchable, low-hysteresis, and dual-mode antibacterial composite hydrogels for wound healing by Yanyan Li, Weiqi Kang, Jian Zhang, Ping Shi, Jianshu Li, Yongping Lu

“…Wound care always presents challenges as they are susceptible to bacterial infections and have mechanical compatibility issues with wound dressings, leading to a delayed recovery of the structure and functional integrity of skin tissue. …”
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Green Strategy–Based Synthesis of Silver Nanoparticles for Antibacterial Applications by Keneth Iceland, Kasozi

“…They are routinely used to treat bacterial infections and to prevent infections in patients with compromised immune systems and enhancing growth in livestock. …”
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Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis by Xueqin Huang, Yingqi Yang, Hanlin Zhou, Liping Hu, Annan Yang, Hua Jin, Biying Zheng, Jiang Pi, Jun Xu, Pinghua Sun, Huai-Hong Cai, Xujing Liang, Bin Pan, Junxia Zheng, Haibo Zhou

“…Rapid and ultrasensitive detection of pathogen-associated biomarkers is vital for the early diagnosis and therapy of bacterial infections. Herein, we developed a close-packed and ordered Au@AgPt array coupled with a cascade triggering strategy for surface-enhanced Raman scattering (SERS) and colorimetric identification of the Staphylococcus aureus biomarker micrococcal nuclease (MNase) in serum samples. …”
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Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

“…Despite the antimicrobial activities of α-defensins by direct bacterial killing and by modulation of immune responses, AATD individuals are paradoxically burdened by recurrent exacerbation triggered by bacterial infections, frequently with nontypeable Haemophilus influenzae (NTHi). …”
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Implementation of a rapid host-protein diagnostic test for distinguishing bacterial and viral infections in adults presenting to urgent care centers: a pragmatic cohort study by Boaz Kalmovich, Daniella Rahamim-Cohen, Ilan Yehoshua, Sara Kivity, Noam Orvieto, Shirley Shapiro Ben David

“…MMBV indicated 405/3262 (12.4%) cases of potentially missed bacterial infections. Physicians prescribed antibiotics to 283/405 (69.9%). …”
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