Regression equation analysis enhances detection of conduction slowing beyond axonal loss in diabetic neuropathy by Nizar Souayah, Zhao Zhong Chong, Tejas Patel, Abu Nasar, Ankit Pahwa, Howard W Sander

“…Background: Causes of conduction slowing beyond pure axonal loss has been attributed to an additional demyelinating component. …”
Get full text

Mimicking Axon Growth and Pruning by Photocatalytic Growth and Chemical Dissolution of Gold on Titanium Dioxide Patterns by Fatemeh Abshari, Moritz Paulsen, Salih Veziroglu, Alexander Vahl, Martina Gerken

“…Axon pruning, i.e., the removal of exuberant axonal connections, is essential in network remodeling. …”
Get full text

Folate-mediated transgenerational inheritance of sperm DNA methylation patterns correlate with spinal axon regeneration by Andy Madrid, Joyce Koueik, Ligia A. Papale, Roy Chebel, Isabelle Renteria, Emily Cannon, Kirk J. Hogan, Reid S. Alisch, Bermans J. Iskandar

“…Sibship-specific DMPs annotate to genes that participate in axon- and synapse-related pathways.…”
Get full text

Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination by Xinyu Fang, Chaofan Zhang, Chongjing Zhang, Yuanqing Cai, Zibo Yu, Zida Huang, Wenbo Li, Wenming Zhang

“…In peripheral nerve injuries (PNIs) in which proximal axons do not regenerate quickly enough, significant chronic degeneration of Schwann cells (SCs) can occur at the distal stump of the injured nerve and obstruct regeneration. …”
Get full text

Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration by Wen Jie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao

“…Abstract Sterile alpha and Toll/interleukin-1 receptor motif containing 1 (SARM1), a nicotinamide adenine dinucleotide (NAD)-utilizing enzyme, mediates axon degeneration (AxD) in various neurodegenerative diseases. …”
Get full text

Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway by Samar Ahmad, Tania Christova, Melanie Pye, Masahiro Narimatsu, Siyuan Song, Jeffrey L. Wrana, Liliana Attisano

Subjects: Get full text

The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury by Shmma Quraishe, Lindsey H. Forbes, Melissa R. Andrews

“…After injury, however, CSPGs and tenascins contribute to the structure of the inhibitory glial scar, which actively prevents axonal regeneration. Myelin sheaths and mature adult oligodendrocytes, despite their important role in signal conduction in mature CNS axons, contribute to the inhibitory environment existing after injury. …”
Get full text

Neuronal glycolysis: focus on developmental morphogenesis and localized subcellular functions by Gianluca Gallo

Subjects: Get full text

Peripheral cranio-spinal nerve communication for trapezius muscle control using axonal profiling through immunostaining by Miri Kim, In-Seung Yeo, Tae-Hyeon Cho, Ju-Eun Hong, Shin Hyung Kim, Hun-Mu Yang

Subjects: Get full text

Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury by Baoguo Liu, Sumei Liu, Dejun Sun

“…Axonal regeneration has been the research focus in the field of clinical treatment for spinal cord injury (SCI). …”
Get full text

AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury by Wen-Yuan Li, Ying Wang, Feng-Guo Zhai, Ping Sun, Yong-Xia Cheng, Ling-Xiao Deng, Zhen-Yu Wang

“…DPSN axons mediate and maintain a variety of normal spinal functions. …”
Get full text

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats by Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano

“…Together with histological features at the lesion site, such as more abundant and larger blood vessels and more abundant, longer and more homogeneously distributed axons, our results corroborate that rGO scaffolds create a permissive environment that allows the invasion of functional axonic processes from neurons located in brainstem nuclei with motor function in a rat model of complete thoracic transection. …”
Get full text

GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand by Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki

Subjects: “…axon regeneration…”
Get full text

Basement membranes are crucial for proper olfactory placode shape, position and boundary with the brain, and for olfactory axon development by Pénélope Tignard, Karen Pottin, Audrey Geeverding, Mohamed Doulazmi, Mélody Cabrera, Coralie Fouquet, Mathilde Liffran, Jonathan Fouchard, Marion Rosello, Shahad Albadri, Filippo Del Bene, Alain Trembleau, Marie Anne Breau

Subjects: Get full text

Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

Get full text

Author Correction: In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axons by Wanjie Wu, Yingzhu He, Yujun Chen, Yiming Fu, Sicong He, Kai Liu, Jianan Y. Qu

Get full text

Severe acute axonal neuropathy following treatment with arsenic trioxide for acute promyelocytic leukemia: a case report by Marcus Kuhn, Mithia Nabergoj, Kety Sammartin, Fabrizio Vianello

“…A more severe chronic sensorimotor polyneuropathy characterized by distal axonal-loss neuropathy can be seen in chronic arsenic exposure. …”
Get full text

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation by Minghui Tan, Caihui Cha, Yongheng Ye, Jifeng Zhang, Sumei Li, Fengming Wu, Sitang Gong, Guoqing Guo

“…CRMP2 and CRMP4 also interacted with one another coordinately to promote growth cone development and axonal elongation. Genetic silencing of CRMP2 enhanced, whereas overexpression of CRMP2 suppressed, the inhibitory effects of CRMP4 knockdown on axonal development. …”
Get full text

GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

“…Abstract Axonal fusion represents an efficient way to recover function after nerve injury. …”
Get full text

Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats by Yonglin Zhao, Yahui Zhao, Ming Zhang, Junjie Zhao, Xudong Ma, Tingqin Huang, Honggang Pang, Jiaxi Li, Jinning Song

“…Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. …”
Get full text