Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay by Or Steg Saban, Shannon M. Vandriel, Syeda Aiman Fatima, Celine Bourdon, Amrita Mundh, Vicky L. Ng, Simon C. Ling, Robert H.J. Bandsma, Binita M. Kamath

“…Standard-of-care therapy in children with autoimmune hepatitis (AIH) includes induction with prednisone 1–2 mg/kg daily with gradual weaning of the dose. …”
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Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report by A. Dalbeni, E. Capoferro, L. Bernardoni, P. Capelli, A. Caliò, A. Gabbrielli, F. Capra

“…We report the case of a 72-year-old female patient who developed a pancolitis with ischemic injury on immunosuppressive treatment with steroids and azathioprine for autoimmune hepatitis. The patient presented with massive rectal bleeding. …”
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Pulmonary and Meningeal Cryptococcosis after Corticosteroid Therapy for Autoimmune Hepatitis: Coexistence of Cryptococci within Pulmonary Cancer Nodule by Takashi Yuri, Ayako Kimura, Katsuhiko Yoshizawa, Yuko Emoto, Yuichi Kinoshita, Airo Tsubura

“…A case of autoimmune hepatitis complicated with pulmonary and meningeal cryptococcosis during long-term treatment with corticosteroid is reported. …”
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Combination Therapy of Ursodeoxycholic Acid and Corticosteroids for Primary Biliary Cirrhosis with Features of Autoimmune Hepatitis: A Meta-Analysis by Yan Zhang, Jie Lu, Weiqi Dai, Fan Wang, Miao Shen, Jing Yang, Rong Zhu, Huawei Zhang, Kan Chen, Ping Cheng, Lei He, Chengfen Wang, Ling Xu, Yingqun Zhou, Chuanyong Guo

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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…This study investigated the role of IL-33 in the pathogenesis of autoimmune hepatitis (AIH). The levels of IL-33/sST2 and Th1/Th2/Th17-type cytokines were determined by enzyme-linked immunosorbent assay in serum samples obtained from 30 AIH patients and 20 healthy controls (HCs). …”
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Postinfantile Giant Cell Hepatitis with Features of Acute Severe Autoimmune Hepatitis Probably Triggered by Diclofenac in a Patient with Primary Myelofibrosis by Pinelopi Arvaniti, Kalliopi Zachou, George K. Koukoulis, George N. Dalekos

“…PIGCH is associated with many diseases, including drugs toxicity, viruses, and autoimmune liver diseases, with autoimmune hepatitis (AIH) being the most prevalent. We present a case of PIGCH in a 76-year-old female without known history of liver disease who suffered from an acute severe episode of hepatitis. …”
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Treatment response rate and life prognosis at autoimmune liver diseases by K. V. Ivashkin, Ye. N. Shirokova, V. T. Ivashkin

Subjects: “…autoimmune hepatitis…”
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Prevalence and clinicopathological Spectrum of Auto-Immune Liver Diseases & Overlap syndrome by Annapoorani Varadarajan, Archana Rastogi, Rakhi Maiwall, Chhagan Bihari, Sherin Thomas, Vikrant Sood, Saggere Muralikrishna Shasthry

Subjects: “…autoimmune hepatitis…”
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Thirteen-Year Follow-Up of a Patient with Liver Cirrhosis Resulting from the Overlap Syndrome of Autoimmune Hepatitis and Primary Biliary Cholangitis: Severe COVID-19 and Liver Transplantation by A. Kh. Odintsova, D. R. Akberova, L. R. Sadykova, N. A. Cheremina, M. M. Minnullin, A. A. Kirshin, E. N. Gabitova, A. Yu. Khasanshina, D. I. Abdulganieva

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15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity by Kan Chen, Jingjing Li, Junshan Wang, Yujing Xia, Weiqi Dai, Fan Wang, Miao Shen, Ping Cheng, Yan Zhang, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Yuanyuan Zheng, Jie Lu, Zhuoyi Fan, Yingqun Zhou, Chuanyong Guo

“…In this study, we investigated both effects of 15d-PGJ2 and its protection mechanism in concanavalin A- (ConA-) induced autoimmune hepatitis in mice. Materials and Methods. In vivo, Balb/C mice were injected with ConA (25 mg/kg) to induce acute autoimmune hepatitis, and 15d-PGJ2 (10 μg or 25 μg) was administered 1 h before the ConA injection. …”
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Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis by Pascal Lapierre, Alain Lamarre

“…As such, it is not surprising that CD4+ regulatory T cells, a key regulatory population of T cells able to curb immune responses, could be involved in both autoimmune hepatitis and chronic viral hepatitis. The liver can induce the conversion of naïve CD4+ T cells to CD4+ regulatory T cells and induce tolerance to locally expressed antigens. …”
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Autoimmune Complications after Hematopoietic Stem Cell Transplantation in Children with Nonmalignant Disorders by Abdalla Khalil, Irena Zaidman, Reuven Bergman, Ronit Elhasid, Myriam Weyl Ben-Arush

“…Autoimmune complications (AICs) after HSCT, such as autoimmune cytopenias, autoimmune hepatitis, primary biliary cirrhosis, and autoimmune cutaneous manifestations, are still neither well defined nor characterized. …”
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Antituberculosis Drug-Induced Liver Injury with Autoimmune Features: Facing Diagnostic and Treatment Challenges by Maria Adriana Rangel, Isabel Pinto Pais, Raquel Duarte, Isabel Carvalho

“…The authors present a case report of antituberculosis drug-induced liver injury that offered diagnostic challenges (namely, the possibility of drug-induced autoimmune hepatitis) and treatment difficulties.…”
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Celiac Crisis in an Adult on Immunosuppressive Therapy by Owayed Al Shammeri, Donald R Duerksen

“…The patient was on corticosteroids and azathioprine for autoimmune hepatitis at the time of her presentation. The current case demonstrates that modest immunosuppression does not prevent a celiac crisis, although previous reports have shown that patients may respond rapidly to high-dose corticosteroids.…”
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Autoantibodies and Liver Disease: Uses and Abuses by Marilyn V Zeman, Gideon M Hirschfield

“…Autoantibodies remain important tools for clinicians, and were the first proposed serological markers to aid in differentiating viral from chronic autoimmune hepatitis. Their presence is occasionally considered to be synonymous with autoimmune liver disease – a misinterpretation of their clinical significance. …”
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Atypical Manifestation of DRESS Syndrome by Christopher Hakim, Constantine Melitas, Eric Nguyen, Kha Ngo

“…The differential for liver transaminases over 1000 units/liter typically includes liver ischemia, acute viral hepatitis, acetaminophen toxicity, and autoimmune hepatitis. Prompt evaluation is imperative as these etiologies can lead to fulminant liver failure. …”
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Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment by L. Yu. Il’chenko, V. I. Reshetn’yak

“…АМА-positive (classical) variant of PBC with pruritus, jaundice, biochemical syndrome of cholestasis and revealing of AMA in diagnostic titer (more 1:40) in blood serum is defined; АМА-negative variant of PBC with lower biochemical and immunologic activity, lower frequency of extrahepatic manifestations, that, however, does not influence the prognosis and terms of LC progression; overlap syndrome with autoimmune hepatitis (AIH) – PBC/AIH (9,4%); asymptomatic course of PBC which is characterized by absence of clinical symptoms for a long period and manifestation of disease at the stage of LC complications. …”
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Veillonella Bacteremia in Alcoholic Hepatitis by Patrick Lee, Brandon K. K. Fields, Tom Liang, Michael P. Dubé, Seth Politano

“…Veillonella species have been correlated with disease severity and hepatic encephalopathy in liver diseases such as autoimmune hepatitis and cirrhosis. Their abundance has also been recently observed to be increased in alcoholic hepatitis, where postinflammatory infections are known to impact mortality. …”
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Recognizing Immunoglobulin G4-Related Overlap Syndromes in Patients with Pancreatic and Hepatobiliary Diseases by Aldo J Montano-Loza, Eoin Lalor, Andrew L Mason

“…It is now recognized that a spectrum of overlap syndromes associated with increased IgG4 and biopsy evidence of IgG4-producing plasma cells, which has now been convincingly linked with cholangitis, autoimmune hepatitis, Sjögren’s syndrome, nephritis and retroperitoneal fibrosis. …”
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Adrenal Insufficiency as a Cause of Acute Liver Failure: A Case Report by Jamshid Vafaeimanesh, Mohammad Bagherzadeh, Mahmoud Parham

“…Common causes include viral and autoimmune hepatitis, fatty liver, and bile duct diseases, but, in uncommon cases like liver involvement in endocrine disorders, liver failure is also seen. …”
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