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241
Beyond the microbiome: unraveling gut dysbiosis and its impact on systemic lupus erythematosus
Published 2025-12-01“…Background Systemic lupus erythematosus (SLE) is an autoimmune disease influenced by genetic and environmental factors, with gut microbiota (GM) changes emerging as a key environmental contributor.Methods A total of 42SLE patients and 30 age – and sex-matched healthy controls were enrolled. …”
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242
Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients
Published 2016-01-01“…The etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. …”
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243
The protein tyrosine phosphatase, nonreceptor type 22-1858C->T (rs2476601) polymorphism is not a genetic risk factor for systemic lupus erythematosus in Indian Tamils
Published 2017-01-01“…Background: Systemic lupus erythematosus (SLE), a systemic autoimmune disease, occurs due to disruption of immune homeostasis against self-antigens. …”
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244
A Novel Insight into the Role of PLA2R and THSD7A in Membranous Nephropathy
Published 2021-01-01“…Membranous nephropathy (MN) is an organ-restricted autoimmune disease mainly caused by circulating autoantibodies against podocyte antigens, including the M-type phospholipase A2 receptor (PLA2R) and thrombospondin domain-containing 7A (THSD7A). …”
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245
Takotsubo Cardiomyopathy and Autoimmune Disorders: A Systematic Scoping Review of Published Cases
Published 2024-01-01“…Most patients had a history of autoimmune disease, and almost a third had a history of cardiovascular disease. …”
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246
Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
Published 2023-01-01“…Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one-third to two-thirds of the patients with SLE progress to lupus nephritis (LN). …”
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247
Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells
Published 2015-01-01“…Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of multiple joints. …”
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248
High-Salt Enhances the Inflammatory Response by Retina Pigment Epithelium Cells following Lipopolysaccharide Stimulation
Published 2015-01-01“…High-salt has been shown to play a role in the pathogenesis of autoimmune disease. In this study, we investigated the effect of high-salt on the production of inflammatory mediators by ARPE-19 cells and the possible mechanisms involved. …”
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249
Autologous Fat Grafting in the Treatment of Facial Scleroderma
Published 2018-01-01“…Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis. …”
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250
Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation
Published 2017-01-01“…Gαq has been found to play an important role in immune regulation and development of autoimmune disease such as rheumatoid arthritis (RA). However, how Gαq participates in the pathogenesis of RA is still not fully understood. …”
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251
Osthole regulates N6‐methyladenosine‐modified TGM2 to inhibit the progression of rheumatoid arthritis and associated interstitial lung disease
Published 2023-04-01“…Abstract Rheumatoid arthritis (RA) is an inflammatory autoimmune disease, and RA interstitial lung disease (ILD) is a severe complication of RA. …”
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252
Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation
Published 2018-01-01“…No significant difference was found in the gender, age, IAIHG score (pretreatment/posttreatment), definite diagnosis rate, extrahepatic autoimmune disease, onset time, or treatment before biopsy between the acute and chronic groups. …”
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253
Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation
Published 2015-01-01“…Myasthenia gravis is an autoimmune disease characterized by muscle weakness. Subjects with antibodies against acetylcholine usually have greater ocular symptoms, lower bulbar weakness, and fewer respiratory complications, compared to individuals with anti-MuSK antibodies. …”
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254
A rare case of recurrent polychondritis with aortic valve involvement
Published 2018-11-01“…The article presents a clinical case of aortic valve disease and recurrent polychondritis (autoimmune disease) with lesions of cartilage tissue in 68-year-old patient admitted to a cardiac surgery clinic due to need for surgical treatment of aortic heart disease. …”
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255
Th17 Cell Enhances CD8 T-Cell Cytotoxicity via IL-21 Production in Emphysema Mice
Published 2012-01-01“…Emphysema is a T-cell mediated autoimmune disease caused predominantly by cigarette smoking. …”
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256
Clinical Outcomes in Patients with Cardiac Lupus: A Retrospective Study
Published 2020-01-01“…Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect every organ system. The study aimed to analyze the clinical manifestations, laboratory findings, antibody associations, and clinical outcomes of patients with cardiac lupus. …”
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257
Abrogation of mercuric chloride-induced nephritis in the Brown Norway rat by treatment with antibodies against TNFα
Published 1995-01-01“…HgCl2 induces an autoimmune disease in the Brown Norway rat characterized by synthesis of autoantibodies (mainly, anti-GBM Abs), severe proteinuria and interstitial nephritis. …”
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258
Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy: Observations with Oral Acitretin
Published 2013-01-01“…Psoriasis is considered to be an inflammatory autoimmune disease, where angiogenesis plays an undefined pathogenetic role. …”
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259
Association of disease activity with programmed cell death 1 and its ligand programmed cell death ligand 1 expressions in lupus patients
Published 2022-01-01“…Background: Programmed cell death 1(PD-1)/programmed cell death ligand 1 (PD-L1) pathway is an immune checkpoint implicated in immune tolerance and involved in the pathogenesis of several autoimmune diseases. Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple immune dysregulation. …”
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260
New treatment options for generalized myasthenia gravis
Published 2024-02-01“…Myasthenia gravis is an autoimmune disease in which autoantibodies against the postsynaptic membrane proteins of the neuromuscular junction disrupt impulse transmission thus causing pathological muscle weakness and fatigue that worsens throughout the day. …”
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