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A Protocol for Diagnosis and Management of Aortic Atherosclerosis in Cardiac Surgery Patients
Published 2017-01-01“…In patients undergoing cardiac surgery, use of perioperative screening for aortic atherosclerosis with modified TEE (A-View method) was associated with lower postoperative mortality, but not stroke, as compared to patients operated on without such screening. …”
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Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery
Published 2012-01-01“…Cardiovascular disease, a leading cause of mortality in developed countries, is mainly caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which differentiate from monocytes that are recruited from the blood, account for the majority of leukocytes in atherosclerotic plaques. …”
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Association of blood pressure and left ventricular mass with subclinical coronary atherosclerosis
Published 2025-02-01“…This study aimed to evaluate the risk factors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovascular disease.Methods The SingHEART study is a population-based cohort in which individuals underwent ambulatory blood pressure (BP) monitoring, cardiac MRI to measure indexed LV mass index (LVMI) and coronary artery calcium (CAC) scoring. …”
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A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation
Published 2019-01-01“…Circulating monocytes play a critical role in the pathogenesis of atherosclerosis. Monocyte homing to sites of atherosclerosis is primarily initiated by selectin. …”
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Association of FMO3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study
Published 2019-01-01“…We included 7,350 European Americans and 2,814 African Americans in the Atherosclerosis Risk in Communities (ARIC) study with exome sequencing of FMO3. …”
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Connexin 37 Regulates the Kv1.3 Pathway and Promotes the Development of Atherosclerosis
Published 2022-01-01“…To investigate the mechanism of Connexin 37 (Cx37) and Kv1.3 pathways in atherosclerosis (AS). Methods. ApoE-/- mice were given a high-fat diet to establish atherosclerosis (AS) model, and macrophages in mice were isolated and extracted to transfect Cx37 vectors with silencing or overexpressing, and Kv1.3 pathway blockers were used to inhibit the pathway activity. …”
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The interventional effect of Polygonatum cyrtonema Hua polysaccharide on atherosclerosis in mice of different sexes
Published 2024-01-01Subjects: Get full text
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Preexisting Cardiovascular Risk Factors and Coronary Artery Atherosclerosis in Patients with and without Cancer
Published 2022-01-01“…Cancer survivors suffer a higher risk of coronary artery atherosclerosis (CAA). Whether cancer patients had increased baseline CAA burden prior to cardiotoxic therapy remains unclear. …”
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Metabolic and epigenetic regulation of macrophage polarization in atherosclerosis: Molecular mechanisms and targeted therapies
Published 2025-02-01Subjects: Get full text
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Infection‐Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study
Published 2025-02-01“…Methods and Results We studied 14 468 adults aged 45 to 64 years in the ARIC (Atherosclerosis Risk in Communities) Study who were HF free at visit 1 (1987–1989). …”
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A minimally invasive animal model of atherosclerosis and neointimal hyperplasia for translational research
Published 2025-02-01“…Abstract Background A variety of animal models has been developed for research on atherosclerosis and neointimal hyperplasia. While small animal models contain limits for translational research, we aimed to develop an atherosclerosis model with lumen-narrowing plaques to foster basic research in vascular biology, the development of new angioplasty devices, and vessel wall imaging approaches. …”
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Gender Conditioning and Socio-economical Condition: its Association with Some Risk Factors for Atherosclerosis
Published 2018-02-01“…The variables analyzed were atherosclerosis risk factors (arterial hypertension, diabetics mellitus type II, smoking habit, total obesity, abdominal obesity) socio-economical and gender overloading. …”
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Predictors and outcomes of angioplasty and stenting in acute intracranial atherosclerosis-related vertebrobasilar artery occlusion
Published 2025-02-01Subjects: Get full text
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75
Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA)
Published 2025-12-01“…To identify the DNAm sites across the epigenome that are associated with discrimination, we conducted epigenome-wide association analyses (EWAS) of three discrimination measures (everyday discrimination, race-related major discrimination, and non-race-related major discrimination) in 1,151 participants, including 565 non-Hispanic White, 221 African American, and 365 Hispanic individuals, from the Multi-Ethnic Study of Atherosclerosis (MESA). We conducted both race/ethnicity-stratified analyses as well as trans-ancestry meta-analyses. …”
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Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis
Published 2014-01-01“…Several markers including osteoprotegerin have been shown to be involved in the development and progression of atherosclerosis. We investigated the relationship between T-cell phenotype, osteoprotegerin, and atherosclerosis evaluated by carotid intima-media thickness (c-IMT) in 94 HIV+ patients on suppressive antiretroviral therapy with Framingham score <10%. …”
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Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits
Published 2014-01-01“…Increased plasma levels of C-reactive protein (CRP) are closely associated with cardiovascular diseases, but whether CRP is directly involved in the pathogenesis of atherosclerosis is still under debate. Many controversial and contradictory results using transgenic mice and rabbits have been published but it is also unclear whether CRP lowering can be used for the treatment of atherosclerosis. …”
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Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation
Published 2025-01-01Subjects: “…Atherosclerosis…”
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