Interleukin-1-Beta and Dyslipidemic Syndrome as Major Risk Factors for Thrombotic Complications in Type 2 Diabetes Mellitus by Oana Bădulescu, Codruţa Bădescu, Manuela Ciocoiu, Magda Bădescu

“…Diabetes mellitus (DM) is a complex disease characterized by chronic hyperglycemia, a known risk factor for accelerated atherosclerosis and vascular disease. The aim of this study was to show that the connection between DM and other risk factors, such as dyslipidemia, inflammatory phenomena, or the development of certain vascular injuries, leads to a high frequency of thrombotic events in diabetic patients compared to the nondiabetic population. …”
Get full text

Evaluation of Interleukin-23 and Creatine Kinase –MB (CK-MB) Levels in Acute Coronary Syndrome Patients with COVID-19 in Baghdad City by Zahraa kareem Yaseen, Farhan Abood Risan, Suhad Hassan Aubaid

“… Acute coronary syndrome (ACS) is considered a common cardiovascular disease, in which there is a blood supply reduction to the myocardium, mostly due to atherosclerosis in the coronary arteries. the present study was designed to detect serum markers in Acute coronary syndrome patients infected with COVID-19 in Baghdad Governorate, by evaluating the level of Interleukin-23(IL-23) and level of creatine kinase isoenzyme (CK-MB). …”
Get full text

Virgin and photo-degraded microplastics induce the activation of human vascular smooth muscle cells by Elisa Persiani, Antonella Cecchettini, Sofia Amato, Elisa Ceccherini, Ilaria Gisone, Agnese Sgalippa, Chiara Ippolito, Valter Castelvetro, Tommaso Lomonaco, Federico Vozzi

“…Since vascular smooth muscle cells (VSMCs) are crucial to maintaining vascular function, this study examined how MPs activate VSMCs, leading to cardiovascular diseases like atherosclerosis and vascular calcification. The study used polyethylene (PE) and polystyrene (PS), common in food packaging, as “virgin” or photo-degraded to simulate environmental conditions. …”
Get full text

Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway by Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia

“…Oxidized low-density lipoprotein (ox-LDL) is derived from circulating LDL and promotes atherosclerosis. The Keap1-Nrf2-ARE pathway is a key body pathway involved in protection against internal and external oxidative damages. …”
Get full text

Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway by Huabing Yang, Pengjun Zhao, Shiliu Tian

“…Oxidative stress plays an imperative role in inflammation, diabetes mellitus, atherosclerosis, and cancer. In the present study, human aortic endothelial cells (HAECs) were employed to explore the anti-inflammatory activity of INN. …”
Get full text

Thicker Carotid Intima Media Thickness in Children with Monocyte Chemoattractant Protein-1: A-2138T and A-2464G Mutation by Yuyun Yueniwati, Valentina Yurina, Mohammad Rasjad Indra

“…Carotid intima media thickness (CIMT) is clearly associated with atherosclerosis. Studies in ischemic stroke patients reveal that there is a significant association between CIMT with monocyte chemoattractant protein-1 (MCP-1) and osteopontin (OPN) promoter polymorphism. …”
Get full text

Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells by Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt

“…Cathepsins are powerful elastases and collagenases secreted by endothelial cells and monocyte-derived macrophages in atherosclerosis, but their involvement in sickle cell disease has not been studied. …”
Get full text

C-Reactive Protein in Human Atherogenesis: Facts and Fiction by Oliver Zimmermann, Kefei Li, Myron Zaczkiewicz, Matthias Graf, Zhongmin Liu, Jan Torzewski

“…The role of C-reactive protein (CRP) in atherosclerosis is controversially discussed. Whereas initial experimental studies suggested a pathogenic role for CRP in atherogenesis, more recent genetic data from Mendelian randomization trials failed to provide evidence for a causative role of CRP in cardiovascular disease. …”
Get full text

The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases by Margarete Dulce Bagatini, Alessandra Antunes dos Santos, Andréia Machado Cardoso, Aline Mânica, Cristina Ruedell Reschke, Fabiano Barbosa Carvalho

“…Among the best known of these diseases are atherosclerosis, hypertension, cancer, epilepsy, Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS). …”
Get full text

Rheumatic Diseases and Obesity: Adipocytokines as Potential Comorbidity Biomarkers for Cardiovascular Diseases by Rossana Scrivo, Massimiliano Vasile, Ulf Müller-Ladner, Elena Neumann, Guido Valesini

“…RA is characterized by systemic inflammation, which is thought to play a key role in accelerated atherosclerosis and in the increased incidence of cardiovascular disease, an important comorbidity in patients with RA. …”
Get full text

Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease by Vincenzo Panichi, Alessia Scatena, Massimiliano Migliori, Valentina Marchetti, Sabrina Paoletti, Sara Beati

“…A role for chronic inflammation has been well established in the development of atherosclerotic disease, and, on the basis of these observations, atherosclerosis might be considered an inflammatory disease. …”
Get full text

Robust Automated Harmonization of Heterogeneous Data Through Ensemble Machine Learning: Algorithm Development and Validation Study by Doris Yang, Doudou Zhou, Steven Cai, Ziming Gan, Michael Pencina, Paul Avillach, Tianxi Cai, Chuan Hong

“…This approach was built off 3 National Institutes of Health cohorts, including the Cardiovascular Health Study, the Multi-Ethnic Study of Atherosclerosis, and the Women’s Health Initiative. We also used gold standard labels to further refine the embeddings in a supervised manner. …”
Get full text

Evaluation of adipocytokines and oxidative stress biomarkers in sera of hemodialysis patients by Shahad F. Obeid, Israa Abass Rashed, Mohammed S. Al-Hindawi

“…In conclusion, adipocytokine parameters and oxidative stress markers have been found to be abnormal in hemodialysis patients and have an effect on atherosclerosis and heart failure progression. [ J Adv Biotechnol Exp Ther 2025; 8(1.000): 79-90]…”
Get full text

Swirling Flow and Wall Shear: Evaluating the BioMimics 3D Helical Centerline Stent for the Femoropopliteal Segment by Timothy M. Sullivan, Thomas Zeller, Masato Nakamura, Colin G. Caro, Michael Lichtenberg

“…Whereas conventional straight stents reduce arterial curvature and disturb blood flow, creating areas of low wall shear, where neointimal hyperplasia predominantly develops, the helical centerline geometry of the BioMimics 3D maintains or imparts arterial curvature, promotes laminar swirling blood flow, and elevates wall shear to protect against atherosclerosis and restenosis. In the multicenter randomized MIMICS trial, treatment of femoropopliteal disease with the BioMimics 3D (n=50) significantly improved 2-year primary patency (log-rank test p=0.05) versus a control straight stent (n=26), with no cases of clinically driven target lesion revascularization between 12 and 24 months (log-rank test p=0.03 versus controls). …”
Get full text

The role of non-alcoholic fatty liver disease in the formation of atherosclerotic vascular lesions in patients with abdominal obesity by N. L. Denisov, V. B. Grinevich, Ye. V. Chernetsova, Yu. A. Kravchuk, K. V. Ivashkin

“…The relationship between the presence of NAFLD, initial manifestations of atherosclerosis and insulin resistance was established. …”
Get full text

The Relationship among Physical Activity, Intestinal Flora, and Cardiovascular Disease by Qiuyu Yan, Wenhui Zhai, Chenghao Yang, Zihao Li, Longfei Mao, Mingyi Zhao, Xiushan Wu

“…Cardiovascular diseases (CVDs), which are associated with high morbidity and mortality worldwide, include atherosclerosis (AS), hypertension, heart failure (HF), atrial fibrillation, and myocardial fibrosis. …”
Get full text

Carotid artery stenosis and ischemic cerebrovascular events after radiotherapy in patients with head and neck cancer. by Nawaphan Taengsakul, Padungcharn Nivatpumin, Thong Chotchutipan, Sunanta Tungfung

“…Data on risk factors for atherosclerosis, medications used, and radiotherapy were also collected. …”
Get full text

Correlation of Circulating Acid-Labile Subunit Levels with Insulin Sensitivity and Serum LDL Cholesterol in Patients with Type 2 Diabetes: Findings from a Prospective Study with Ro... by Ying-Chuen Lai, Hung-Yuan Li, Ta-Jen Wu, Chi-Yuan Jeng, Lee-Ming Chuang

“…Reduction of ALS by RSG increases the risk of atherosclerosis in individuals with type 2 diabetes.…”
Get full text

Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers by Matthaios Speletas, Vassiliki Merentiti, Konstantinos Kostikas, Kyriaki Liadaki, Markos Minas, Konstantinos Gourgoulianis, Anastasios E. Germenis

“…For this purpose we investigated the prevalence and any possible associations of common TLR polymorphisms (𝑇𝐿𝑅2-R753Q, 𝑇𝐿𝑅4-D299G, and 𝑇𝐿𝑅4-T399I) in a group of 240 heavy smokers (>20 pack years), without overt atherosclerosis disease, of whom 136 had developed COPD and 104 had not. …”
Get full text

Detection of Coronary Artery Disease by an Erectile Dysfunction Questionnaire by Mehrab Sayadi, Reza Elmafshar, Iman Razeghian-Jahromi, Mohammad Javad Zibaeenezhad

“…Other than CAD, ED could be considered as one of the manifestations of atherosclerosis. Accordingly, the IIEF questionnaire is a useful tool to early diagnosis of CAD. …”
Get full text